131 companies · SBIR/STTR awards, last two years
Every company in Maryland that closed a federal SBIR/STTR award in the last two years: those with open roles on our board first, then newest award first. Back to the Maryland page
Easton, MD · 35 employees · Department of Defense · Phase I · company site
“Fusing 5D Virtualization Technology with Advanced Robotics to Enhance Air Force Readiness”
Cockeysville, MD · 15 employees · Department of Defense · Phase I · company site
“Captive Carry Transponder for the Terminal High Altitude Area Defense (THAAD) Interceptor”
Davidsonville, MD · 6 employees · Department of Defense · Phase I · company site
“N252-105-0130 MICROCAST: A Unified Hybrid Forecasting System for Naval Operations”
Kensington, MD · 3 employees · Department of Defense · Phase I/II
“High-Fidelity Multiphase-Peridynamics Solver for Hypersonic Vehicle Analysis in Adverse Weather Conditions for GPUs”
Boyds, MD · 5 employees · Department of Defense · Phase I · woman-owned
“RECAP: Rapid Educational Content Automation Platform Using Multimodal Large Language Models”
Catonsville, MD · 14 employees · Department of Defense · Phase I/II · woman-owned · company site
“ABDREAM: Aircraft Battle Damage Repair: Essential Archive for Maintenance”
Hollywood, MD · 160 employees · Department of Defense, Department of Transportation · Phase I/II · company site
“Scenario-based Range and Mission Optimization Harnessing Mutual Aerodynamic Interaction Between Multiple Aircraft”
Ellicott City, MD · 2 employees · National Science Foundation · Phase I
“SBIR Phase I: AI Powered Invisible Fence to Foster Human-Wildlife Harmony”
Ellicott City, MD · 3 employees · National Science Foundation · Phase I
“SBIR Phase I: Optimizing Quantum Circuit Compiler for Quantum Software and Hardware Developers”
Aberdeen Proving Ground, MD · 38 employees · Department of Defense · Phase II · company site
“Enhanced Security 5G for LEO CJADC2 Networks”
Rockville, MD · 5 employees · Department of Health and Human Services · Phase I/II
“A novel remote blood separation device for at-home plasma collection for HIV-1 testing”
Gaithersburg, MD · 11 employees · Department of Commerce, Department of Defense, Department of Energy, Department of Transportation, National Aeronautics and Space Administration · Phase I/II · company site
“Detect3C: Advancing the Assessment of Concrete Chloride Content Through Non-Destructive Techniques”
Gaithersburg, MD · 4 employees · Department of Health and Human Services · Phase II
“IND-Enabling Development of HIV Maturation Inhibitors Formulated for use as either Oral or Long-Acting Parenterally Administered Agents”
Owings Mills, MD · 15 employees · Department of Defense · Phase II
“FireSky FX: Edge-Deployed Cyber Effects Platform”
Reisterstown, MD · 6 employees · Department of Health and Human Services · Phase I · company site
“BLiPS: Biocompatible Liver in Pigs”
Frederick, MD · 5 employees · Department of Health and Human Services · Phase II · company site
“Development of Cobinamide as a Cyanide Antidote: Completion of pre-IND Studies”
Ellicott City, MD · 5 employees · Department of Health and Human Services · Phase II · company site
“Drug development of RK-33 for breast cancer treatment”
Brookeville, MD · 4 employees · Department of Health and Human Services · Phase II
“Title: Developing a novel drug for neurobehavioral deficits in FASD”
Potomac, MD · 0 employees · Department of Health and Human Services · Phase I/II
“Digital Accessible Remote Olfactory Mediated Health Assessments forPreclinical AD”
Bethesda, MD · 4 employees · Department of Health and Human Services · Phase I
“Leveraging Large Language Models to Enhance Regional Genomic Medicine eConsults”
Columbia, MD · 6 employees · Department of Health and Human Services · Phase I
“Imaging of Neurovascular Response for Assessment of Alzheimer's Disease”
Laurel, MD · 75 employees · National Aeronautics and Space Administration · Phase I · company site
“High-Speed Photonic Integrated Analyzer for Unconditionally Entangled and Noise Squeezed Quantum States”
Columbia, MD · 32 employees · Department of Defense · Phase II · company site
“Recognized Cyberspace Picture (RCyP): Empowering Intelligence Analysts Through AI-Driven Cyber Triage and Attribution”
Annapolis Junction, MD · 20 employees · Department of Defense, National Aeronautics and Space Administration · Phase I · woman-owned · company site
“ASCENT - Autonomous Software Certification & Evaluation for New Technologies”
Baltimore, MD · 4 employees · Department of Health and Human Services · Phase II · company site
“Development of Mi-Helper: A Thermodynamic Neuromodulation Device for Migraine Relief”
Baltimore, MD · 15 employees · Department of Health and Human Services · Phase II · company site
“Bloodstream infection detection directly on whole blood”
College Park, MD · 5 employees · Department of Defense, National Aeronautics and Space Administration · Phase I · company site
“Robust All-Optical Solid-State Magnetometer for Space”
Germantown, MD · 4 employees · Department of Education · Phase I · company site
“Transforming STEM Learning: Local Ecosystems as Classrooms”
Greenbelt, MD · 12 employees · Department of Defense, National Aeronautics and Space Administration · Phase I · company site
“Vertically Integrated Silicon Carbide/Silicon Detectors for UV/Vis Multicolor Sensing”
Bethesda, MD · 2 employees · Department of Health and Human Services · Phase II · company site
“Engineered Glioblastoma-specific T cells using Immunostimulatory Photothermal Nanoparticles”
National Harbor, MD · 3 employees · Department of Health and Human Services · Phase I
“Investigating the safety and efficacy of pillararene sulfates as novel and effective reversal agents for both steroidal and non-steroidal ne”
Frederick, MD · 6 employees · Department of Defense · Phase II · woman-owned · company site
“TriSense: An AI-Powered VOC Sensing System for Culture-Free Infection Diagnosis in biofluids”
Columbia, MD · 14 employees · National Aeronautics and Space Administration · Phase I · company site
“The Pandora-Inspired Advanced Hyperspectral Camera for Atmospheric Monitoring (PANCAM)”
Silver Spring, MD · 20 employees · Department of Health and Human Services · Phase II · company site
“AT191: An inhaled & precision RNA therapeutic with pan-variant SARS-CoV-2 efficacy”
Belcamp, MD · 1 employee · Department of Defense · Phase II · company site
“Poison Arrow: AI Cyber Adversary Simulation for AF Cyber Ranges”
Annapolis, MD · 5 employees · Department of Health and Human Services · Phase II · company site
“Clinical Evaluation of an Alarm Activated Detection System to Enable Early Intervention of Emerging Respiratory Decline with the Linshom Med”
Lusby, MD · 9 employees · National Aeronautics and Space Administration · Phase I · company site
“AI-Enhanced Digital Twin Framework for UAS Component Reliability in Support of In-Time Aviation Safety Management Systems (IASMS)”
Laurel, MD · 3 employees · National Aeronautics and Space Administration · Phase I · company site
“Lunar Digital Twin”
Sparks, MD · 60 employees · Department of Defense · Phase I/II · company site
“Non-Contact High-Resolution All-Optical Handheld Ultrasound Imaging System”
Woodbine, MD · 2 employees · Department of Health and Human Services · Phase II · company site
“Novel Gene Therapy, Techniques, and Devices to Prevent Ventricular Tachycardia”
Hyattsville, MD · 2 employees · Department of Defense · Phase II · company site
“AcquisitionFlow: Comprehensive and Automated Market Research for Acquisition Officers”
Halethorpe, MD · 2 employees · Department of Health and Human Services · Phase I · woman-owned
“Synthetic circular supercoiled DNA: an alternative to plasmids for the production of lentiviral vectors for cell and gene therapies”
Potomac, MD · 1 employee · Department of Health and Human Services · Phase I · woman-owned · company site
“Preclinical validation of AVGN7 for treating obesity and type 2 diabetes mellitus.”
Bethesda, MD · 0 employees · Department of Health and Human Services · Phase II
“Efficacy of Hypoxic Red Blood Cells Processed with the Hemanext ONE® System in Patients with Sickle Cell Anemia”
Gambrills, MD · 5 employees · National Aeronautics and Space Administration · Phase I/II · woman-owned · company site
“Integrated Surface and Approach Risk Monitor”
Baltimore, MD · 6 employees · Department of Health and Human Services · Phase II · woman-owned
“Low Cost Carbon Dioxide-Based Cryoablation for Breast Cancer Treatment in Low Resource Settings”
Baltimore, MD · 6 employees · Department of Health and Human Services · Phase II · company site
“Bilateral Acoustic Sensing and Automated Breathing Segmentation for Remote Monitoring of Patients with COPD: A Longitudinal Study”
Linthicum Heights, MD · 5 employees · Department of Health and Human Services · Phase II
“Facilitating neuroplastic changes of acute stroke survivors with severe hemiplegia”
College Park, MD · 6 employees · Department of Health and Human Services · Phase I · woman-owned · company site
“AI-Based Speech Enhancement for Hearing Aids”
Silver Spring, MD · 6 employees · Department of Defense, National Science Foundation · Phase II · company site
“SBIR Phase II: Innovative Solid-State Phase Change Cooling to Supercharge Central Processing Unit (CPU) Performance”
Gaithersburg, MD · 13 employees · Department of Defense · Phase I · company site
“RAPIDS: Robotic Autonomous Platform Sensors for Intelligent Distributed Bridging Operations”
Derwood, MD · 27 employees · Department of Defense · Phase I · company site
“DOD Artificial Intelligence Pricing and Supply Chain Risk Management Tool”
Laurel, MD · 13 employees · Department of Defense · Phase I · company site
“Synthetic Data Generator Solution_UVS InfoTech LLC”
Annapolis, MD · 28 employees · Department of Defense · Phase II · company site
“TBD”
Clarksburg, MD · 326 employees · Department of Defense · Phase II · company site
“Dual-Use Voice Command Autonomy”
Rockville, MD · 8 employees · Department of Defense · Phase II · woman-owned · company site
“Optimization and Validation of a Hydrogel-Based Wearable Cortisol Sensor for Continuous Soldier Load Monitoring”
Beltsville, MD · 16 employees · National Aeronautics and Space Administration · Phase I · company site
“Gravity-Independent Heat Exchangers and Oil-Free Compressors for Modular Refrigeration System”
Baltimore, MD · 2 employees · Department of Health and Human Services · Phase II
“BCG overexpressing a small molecule STING agonist as a vaccine for TB”
Pikesville, MD · 3 employees · Department of Health and Human Services · Phase II · company site
“Non Magnetic MRI Conditional External Defibrillator with Reduced Skeletal Muscle Contraction”
Glen Burnie, MD · 3 employees · Department of Defense · Phase I · woman-owned · company site
“Generative AI BAA Open Topic”
Gaithersburg, MD · 12 employees · Department of Transportation · Phase I
“Non-Contact Ultrasonic System for Measuring Rail Neutral Temperature”
Bethesda, MD · 4 employees · Department of Defense, Department of Transportation · Phase I/II · company site
“GeoRAG: Spatial Reasoning of Modern LLMs Combined With Retrieval-Augmented Generation (RAG) for On-The-Fly Geospatial Dataset Generation”
Baltimore, MD · 11 employees · Department of Defense · Phase II · company site
“Production of GLP ErythroMer for IND Enabling Animal Studies”
Ellicott City, MD · 13 employees · Department of Defense, Department of Homeland Security · Phase I/II · company site
“Wireless Vehicle Sensor Network for Predictive Logistics”
Rockville, MD · 8 employees · Department of Health and Human Services · Phase II · woman-owned
“Commercialization Readiness Pilot for A Comprehensive Platform for Pediatric Cranial Evaluation”
Halethorpe, MD · 2 employees · Department of Health and Human Services · Phase II · company site
“FDA Phase 1 Development of a Novel Nonopioid Cell and Tissue Permeable Peptide Therapeutic for Epigenetic Reprogramming of Neuropathic Pain”
Bethesda, MD · 2 employees · Department of Health and Human Services · Phase I · woman-owned · company site
“Long-read sequencing-based diagnosis for complex genomic and DNA methylation changes”
Lutherville Timonium, MD · 1 employee · Department of Health and Human Services · Phase I
“Preclinical Development of a Therapeutic Antibody for Type-1 Diabetes”
Bethesda, MD · 15 employees · Department of Health and Human Services · Phase I · company site
“AI-driven in vivo profiling in zebrafish: a platform for alcohol use disorder therapeutic discovery”
Beltsville, MD · 10 employees · Department of Defense, Department of Energy · Phase I/II · company site
“Active Distributed Pump Signal Combiner for High Power Fiber Laser”
Columbia, MD · 135 employees · Department of Defense · Phase I · woman-owned · company site
“Large Language Models for System Security Engineering Analysis”
Bowie, MD · 10 employees · Department of Defense · Phase I/II · company site
“TRIDENT (Trusted Routing Interoperable Defense Enterprise Naval Toolset)”
Baltimore, MD · 2 employees · Department of Health and Human Services · Phase II · woman-owned
“A Point of Care Urine Test to Aid Diagnosis of Aspergillosis”
Annapolis, MD · 78 employees · Department of Defense · Phase I/II · company site
“ConTrack: Smart Contracts for SCRM”
Woodbine, MD · 45 employees · Department of Defense · Phase II · company site
“Scalable Techniques for Center-of-Mass and Course-of-Action Analytics for Intelligence Preparation of the Battlefield”
Frederick, MD · 12 employees · Department of Health and Human Services · Phase I · company site
“Immersive Escape Room Gamification: Transportation Hazmat Incident (iERG)”
Baltimore, MD · 3 employees · Department of Defense · Phase II · company site
“Anti-Shock Injection to Improve Combat Casualty Care”
Millersville, MD · 26 employees · Department of Defense · Phase I/II · company site
“Passive Acoustics Sonobuoys Intelligence and Machine Learning”
Lexington Park, MD · 264 employees · Department of Defense · Phase II · company site
“Direct to Phase II Passive Acoustics Sonobuoys Intelligence & Machine Learning”
Severn, MD · 11 employees · Department of Defense · Phase II · company site
“QUOLAB XSIAM: CYBERSECURITY AUTOMATION & COLLABORATION”
Forest Hill, MD · 5 employees · Department of Defense · Phase I
“Drapable Advanced Forming of Thermoplastics (DrAFT)”
Beltsville, MD · 15 employees · Department of Defense, Department of Energy · Phase I · company site
“A 100MW X-band Short Pulse Phase Shifter”
Annapolis, MD · 36 employees · Department of Defense · Phase II · company site
“Weaving Together Enhanced Kill-Webs through Model Based Systems Engineering, Agent Based Modeling and Simulation, and Advanced Analytics”
Calverton, MD · 8 employees · Department of Defense · Phase II · company site
“Development of a Junctional Tourniquet”
Rockville, MD · 12 employees · Department of Defense · Phase I/II · company site
“Assured, Resilient Containerization and Orchestration Solution (ARCOS)”
Sykesville, MD · 18 employees · Department of Defense · Phase II · company site
“Modular Aerosol Sampler for Microsensors”
Baltimore, MD · 8 employees · Department of Health and Human Services, National Science Foundation · Phase I/II · company site
“SBIR Phase II: Hybrid DNA-Protein Quantification Platform for Point-of-Care Diagnosis”
Potomac, MD · 23 employees · Department of Defense · Phase II · company site
“Generative AI-Driven Defense and Machine Learning Against Advanced Phishing Attacks TACFI”
Westminster, MD · 6 employees · Department of Defense · Phase II · company site
“Next Generation Naval Design Tools”
Baltimore, MD · 1 employee · Department of Health and Human Services · Phase II
“Development of VNPP433-3Beta as Novel Therapeutic for All Stages of Prostrate Cancer”
Baltimore, MD · 0 employees · Department of Health and Human Services · Phase I
“Use of HIF-1alpha mRNA to Promote Pedicle Flap Healing.”
Towson, MD · 3 employees · Department of Health and Human Services · Phase I
“ND Enabling Studies for CMT-101, a Novel Gene Therapy for Glycogen Storage Disease 1b”
Rockville, MD · 15 employees · Department of Health and Human Services · Phase II
“Monoclonal Antibody Cocktail for Treatment of Marburg Virus Disease”
Pasadena, MD · 28 employees · Department of Defense · Phase II · company site
“Automated Cyber Defense for the USAF Network”
Baltimore, MD · 0 employees · National Science Foundation · Phase I
“SBIR Phase I: Semi-autonomous Image-guided Robotic Suturing System”
Temple Hills, MD · 3 employees · Department of Defense · Phase II · company site
“Autonomous UAS Reconnaissance & Identification System (AURIS)”
Bethesda, MD · 2 employees · Department of Health and Human Services · Phase II · company site
“srvc-EHSR: Sysrev Version Control - Environmental and Health Related Systematic Reviews”
Severna Park, MD · 5 employees · Department of Defense · Phase II
“Guardian Sleep Assessment System: Detecting Microarousals Associated with Leg Movements during Sleep”
Curtis Bay, MD · 450 employees · Department of Defense · Phase II · company site
“USV Rapid Deployment System”
Chevy Chase, MD · 2 employees · Department of Health and Human Services · Phase I · company site
“MyTrials: An Integrated Tool to Support Remote Biomarker Capture within Decentralized Clinical Trials for Substance Use Disorders”
Germantown, MD · 14 employees · Department of Defense · Phase I · woman-owned · company site
“PAISAR: Predictive Antijam Artificial Intelligence Scanned Array Receivers”
Belcamp, MD · 432 employees · Department of Defense · Phase II · company site
“Real-time, cooperative airspace coordination, deconfliction, and approval”
Linthicum Heights, MD · 60 employees · Department of Defense · Phase II · company site
“Unitary Braid Division Multiplexing Tactical Radio Integration”
Bethesda, MD · 6 employees · Department of Defense · Phase II · company site
“The Walacor Platform for Secure Sensor Data and Persistent Data Integrity”
Silver Spring, MD · 2 employees · National Science Foundation · Phase I
“SBIR Phase I: High-Precision Timing Devices for Research and Industry”
Baltimore, MD · 3 employees · National Science Foundation · Phase II
“STTR Phase II: Living Pharmacy for Diabetes and Obesity Treatment”
Germantown, MD · 5 employees · Department of Defense · Phase II · company site
“CONSTELLATION: Portable Reconfigurable Water Tester at Point-of-Need”
Towson, MD · 3 employees · Department of Health and Human Services · Phase II
“Targeted ColQ gene therapy for Congenital Myasthenic Syndromes”
Gaithersburg, MD · 5 employees · Department of Energy · Phase I
“Vibration-free Cryo-electron Tomography using Ultrafast Pulses of Electrons”
Gaithersburg, MD · 12 employees · Department of Energy · Phase I · company site
“Delivery of siRNA-containing tetrahedral RNA nanostructures into bioenergy crops using LDH stabilized sprays”
Baltimore, MD · 4 employees · Department of Health and Human Services · Phase II · company site
“Cloud/Web-Based Platform for Quantitative SPECT Reconstruction of Therapeutic Radionuclides”
Frederick, MD · 14 employees · Department of Defense · Phase I · company site
“Explosion Proof Collaborative Robots”
Kensington, MD · 33 employees · Department of Health and Human Services · Phase II · company site
“SPIRIT Club CBI Pathway: A novel streaming platform for physical activity and wellness promotion for chronic brain injury survivors”
Rockville, MD · 21 employees · Department of Defense · Phase I · company site
“ThreatSHIELD - Configurable Microsensor Suite for Multi-Threat Detection”
Rockville, MD · 200 employees · Department of Defense · Phase I · company site
“RAVEN -? A Unified and Adaptive MBSE Platform Securing and Streamlining Air Force Operations for the Future?”
Bel Air, MD · 10 employees · Department of Defense, Department of Health and Human Services · Phase I/II · company site
“Head-worn low intensity focused ultrasound (LIFU) device for enhancing sleep in substance use disorder (SUD)”
Columbia, MD · 4 employees · Department of Defense · Phase I · company site
“High Trust Cloud Networking Defended by an Automated Moving Target Defense”
Bethesda, MD · 190 employees · Department of Defense · Phase I · company site
“Signal Fusion Platform (SFP) for USAF Dual Purpose Technologies”
Hollywood, MD · 48 employees · Department of Defense · Phase II · company site
“Parraid Outsourcing Workload (O.W.L) Linux Power and Data Hub”
Beltsville, MD · 1 employee · National Science Foundation · Phase I · woman-owned
“SBIR Phase I: World of Hello: Using artificial intelligence (AI) for an interactive language-learning process designed for young children”
Frederick, MD · 8 employees · Department of Health and Human Services · Phase I/II
“A Subunit Vaccine Against Acinetobacter Baumannii”
Lexington Park, MD · 4 employees · Department of Defense · Phase II · woman-owned
“Minotaur Alternate Radio Command and Control Operations - Persistent Operational Links for Overmatch (MARCCO-POLO)”
Hollywood, MD · 2 employees · Department of Defense · Phase I · company site
“Non-Embrittling Selective Stripper of Cadmium and ZInc-Nickel”
Pocomoke City, MD · 92 employees · Department of Defense · Phase I
“Hardwire Laminated Metallic Armor”
Annapolis, MD · 19 employees · Department of Defense · Phase I · company site
“Measuring Autonomy Pilot Interactions (MAPI)”
Annapolis, MD · 100 employees · Department of Defense · Phase I · company site
“Annapolis Proposal for SBIR N242-077: Scalable Wideband Multifunction Radio Frequency (RF) Payloads”
Baltimore, MD · 2 employees · Environmental Protection Agency · Phase II
“Fighting Fires with Filters - Electrospinning Biodegradable Materials for High-Performance Indoor Air Filters”
Baltimore, MD · 4 employees · Department of Defense · Phase I · company site
“Design of a Modular, Multi-Sensor, Multi-Domain Advanced Autonomous Surveillance and Sensing Platform for Enhanced Situational Awareness and”
Germantown, MD · 1 employee · Department of Health and Human Services · Phase I
“EVALUATING HBVZ10-BASED THERAPIED FOR CCCDNA CLEARANCE: VIROLOGICAL FOUNDATION AND SYNERGISTIC COMBINATIONS”
Bethesda, MD · 3 employees · Department of Health and Human Services · Phase II · company site
“Sign Language Detection for Videoconferencing Phase II (SLDVC II).”
Baltimore, MD · 0 employees · Department of Health and Human Services · Phase I · company site
“HandSOME I: Exoskeleton for Assistive Use with Stroke Survivors.”
Source: public SBIR/STTR award record. Company-level facts only. Open roles are live listings on our board.