Sanofi is hiring a Postdoctoral Fellow in the Biophysics & BioNMR/BioAnalytics team (Vitry-sur-Seine) to investigate how post-translational modifications (PTMs) in antibody CDRs affect antigen binding and molecular stability. The project combines experimental structural biology (2D/3D-NMR, cryo-EM, crystallography, HDX-MS) with computational modelling to elucidate how PTMs in CDRs modulate Fab structure and antigen recognition, supporting molecule optimization and manufacturing process development.
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