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Research ScientistData & Computation

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

Isomorphic Labs · Cambridge, Massachusetts, United States

Apply on employer site →Posted September 2, 2026

About the role

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The role involves leading drug discovery programs with AI-first approaches, providing technical and strategic direction while embedding machine learning into computational chemistry workflows — either overseeing the full pipeline as a Program Lead managing external partnerships and milestones, or serving as a Computational Chemistry Lead providing specialized expertise, with some positions also mentoring a team of computational chemists. Candidates should hold a PhD in computational chemistry with 5-8+ years leading drug design programs from hit identification through candidate nomination, strong Python/cheminformatics skills, and a solid publication and patent record.

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