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Research Leader (DMPK), Cambridge, MA

Isomorphic Labs · Cambridge, Massachusetts, United States

Apply on employer site →Posted September 4, 2026

About the role

Isomorphic Labs is hiring a Research Leader to set drug metabolism and pharmacokinetics (DMPK) strategy across its AI-driven drug discovery pipeline, bridging preclinical development with computational prediction models to optimize drug-like properties. Responsibilities include designing stage-appropriate DMPK strategies, integrating pharmacology/toxicology data for decision-making, authoring regulatory documentation, and collaborating with chemistry and pharmacology teams. Requires a PhD in pharmaceutical science or a related field with 7-10+ years of DMPK experience in biotech/pharma, including experience developing pharmacology packages for clinical development. Hybrid role, 3 days per week onsite in Cambridge, MA.

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