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RFA-NS-27-007National Institutes of HealthUG3

HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)

Deadline
Award ceiling
Not stated
Awards
3
Posted
Jun 16, 2026

Official announcement on Grants.gov · opens the funder's page. Always confirm dates there.

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Summary

The NIH HEAL Initiative: This NOFO encourages applications in support of the NIH's Helping to End Addiction Long-term (HEAL) initiative to speed scientific solutions to the national opioid public health crisis…

Related NIH announcements6

Other open UG3 announcements on related subjects, with at least two weeks to go.

NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

PAR-25-188National Institutes of Health3 review criteria on file

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Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)

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NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

PAR-25-057National Institutes of Health6 review criteria on file

—

Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)

PAR-25-311National Institutes of Health3 review criteria on file

$6.3M

Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)

PAR-25-226National Institutes of Health3 review criteria on fileagency framework

—

Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

PAR-25-446National Institutes of Health3 review criteria on fileagency framework

$3M

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Source record: https://www.grants.gov/search-results-detail/359161Via Grants.gov. Last checked against the source . Always confirm dates with the funder.