rare-disease funding
17 open opportunities tagged rare-disease, across federal agencies and private foundations. Sorted by deadline.
Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research (R01 Clinical Trial Optional)
The National Library of Medicine (NLM) wishes to advance groundbreaking and innovative research in bioinformatics, translational bioinformatics and computational biology, which are related areas of biomedical informatics that aim to understand biological data using storage, analytic and interpretive methods.
3 review criteria on fileScreening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)
Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including structural congenital anomalies (SCAs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs).
3 review criteria on fileCausal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)
6 years.25 billion fewer life years for the United States population.
3 review criteria on fileINCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
The INCLUDE Transformative Research Award Program supports collaborative investigative teams or individual scientists who propose unusually innovative research projects, which, if successful, would have a major impact in understanding the biology of Down syndrome or related co-occurring conditions, or development of new treatments for…
3 review criteria on fileINCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)
This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address important gaps in Down syndrome research.
3 review criteria on fileINCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)
Purpose The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome.
3 review criteria on filePilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to elucidate a role for understudied proteins in rare disease. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s).
3 review criteria on fileGREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
Background and Program Overview Over the last decade, rapid advancements in the development of high throughput and cost-effective genome sequencing technologies have made it possible to obtain a precise molecular diagnosis for many individuals with an undiagnosed but likely genetic disease.
3 review criteria on fileGREGoRi Technology Integration Center (U01, Clinical Trials Optional)
Background and Program Overview Over the last decade, rapid advancements in the development of high throughput and cost-effective genome sequencing technologies have made it possible to obtain a precise molecular diagnosis for many individuals with an undiagnosed but likely genetic disease.
3 review criteria on fileGREGoRi Innovation Projects (U01 Clinical Trial Optional)
Background and Program Overview Over the last decade, rapid advancements in the development of high throughput and cost-effective genome sequencing technologies have made it possible to obtain a precise molecular diagnosis for many individuals with an undiagnosed but likely genetic disease.
3 review criteria on fileDiscovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
gov/bill/113th-congress/house-bill/2019/text ), for an initial 10 years, 2015-2024.0 by the 118th Congress for an additional five years, and the program was transferred from The Common Fund to the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI).
7 review criteria on fileOpportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)
The goal of this Notice of Funding Opportunity (NOFO) is to support collaborative, patient-centric translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health., those conducting research in labs and clinics outside of the NIH).
3 review criteria on fileClinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of clinical projects that address critical needs for clinical trial readiness in rare diseases.
3 review criteria on fileAccelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)
Purpose The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access the processed and stored biospecimens from the All of Us Research Program supported Biobank to advance the program's mission of accelerating health research and medical breakthroughs,…
6 review criteria on filePreclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development. In addition to preclinical efficacy, accompanying pharmacodynamic and pharmacokinetic studies would be supported.
3 review criteria on fileReissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs.
4 review criteria on fileReissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
The purpose of this Notice of Funding Opportunity (NOFO) is to fund clinical trials of products evaluating efficacy and/or safety in support of a new indication or change in labeling to address unmet needs in rare diseases or conditions.
4 review criteria on fileSee which rare-disease opportunities fit your work
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