Computational Biologist Principal Research Scientist II

AbbVie is hiring a Computational Biologist, Principal Research Scientist II ($141,500 - $268,500 annually) to lead AI-enabled computational biology efforts establishing next-generation immunogenicity and translational immunology capabilities across biologics discovery and development. The role develops predictive models for preclinical and clinical immunogenicity risk assessment, integrates ADA incidence, PK/PD, HLA, sequence, structure, and patient-level data using machine learning, applies protein language models and generative AI to biologics development, and leads and mentors a team of computational scientists. Requirements include a PhD in computational biology, bioinformatics, computer science, data science, biophysics, or a related field (8+ years' experience) or a Master's degree (14+ years); demonstrated expertise in computational protein science, AI/ML, and predictive modeling; people-management experience leading scientific teams; and proficiency in Python with frameworks such as PyTorch, TensorFlow, or scikit-learn.