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Research ScientistLife Sciences

Scientist II, Delivery for Large Gene Insertion

Profluent Bio · Emeryville, California, United States

Advertised pay
$144,000 - $160,000 USD
Posted
Employer funding
No recent SBIR/STTR award on record
Source
Employer posting · link-checked

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About the role

Profluent Bio, an AI-for-biology company in Emeryville, CA, is hiring a Scientist II on its Platform Discovery team to lead work on non-viral DNA delivery for recombinase-based large gene insertion. The role involves developing quantitative assays to evaluate donor template delivery, designing hypothesis-driven experiments to overcome barriers to template stability and nuclear availability, and collaborating with translational teams to validate approaches in cell-based and in vivo systems. Requires a PhD in molecular biology, biochemistry, or bioengineering plus 2-4 years of experience, expertise in nucleic acid delivery, hands-on molecular cloning, and NGS-based genome editing evaluation.

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