About the role
Bristol Myers Squibb is hiring a Principal Scientist for its Small Molecule Computational Design team within Computational Sciences, to serve as the lead computational scientist on Protein Homeostasis project teams. The role combines computational chemistry, cheminformatics, and machine learning to design and triage degrader and molecular glue chemical matter, applying multi-parameter optimization across potency, selectivity, ternary complex formation, degradation efficiency, and ADME properties, while flagging toxicological risk. The scientist will also develop and deploy predictive models and cheminformatics workflows, integrate structural data (co-crystal structures, cryo-EM, modeled structures) with large-scale data analysis, and steward the group's chemical and biological data resources and tooling.
The role is based in San Diego, CA, with a salary range of $156,890 - $190,117.
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