The Computational Biology Group at CIC bioGUNE seeks a highly skilled and motivated postdoctoral researchers to work on an exciting project that aims at the development of computational approaches for designing neuronal cell conversion protocols. The selected candidate will develop a computational platform to identify hierarchical combinations of cell fate conversion factors, which will in turn be used to engineer highly specialized neuronal subtypes for cell transplantation therapies in animal models of Alzheimer's disease, stroke, and epilepsy. To achieve this goal, the candidate will combine a gene network-based approach with a machine learning model (foundational model) to propose protocols for the sequential induction of transcription factors to generate desired cell subtypes. The selected candidate will be part of a Canadian federal grant project (NFRF) with international collaborators who will conduct experimental validation of the computational predictions to translate neuronal reprogramming into clinical practice.
The Computational Biology Group aims at establishing a solid infrastructure to develop theoretical frameworks for computational modeling of biomedical problems, especially in the areas of stem cell research, aging and disease modeling. The group closely collaborates with leading national and international experimental labs with a particular interest in stem cell research and regenerative medicine.
Essential skills and qualities:
Ph.D. degree in computational biology, bioinformatics, biology, computer science, physics or a related discipline
Strong computational skills in at least one programming language (e.g. R or Python)
A strong publication record in related fields
Excellent communication and working knowledge in English
Ideal skills:
Prior experience in computational systems biology
Prior knowledge about transcriptional regulation and the prediction of cellular conversion factors
Experience in working in a multi-disciplinary research environment
We offer:
Opportunity to do highly interdisciplinary research to solve complex biomedical problems within a dynamic research institution (CIC bioGUNE) and in collaboration with internationally recognized partner
An exciting international environment
Applications should contain the following documents:
A detailed curriculum vitae
A cover letter
Applications should be sent before 15.08.2026 to:
Prof. Dr. Antonio del Sol
E-mail: adelsol@cicbiogune.es
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