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Recently funded science companies in Colorado

138 companies in Colorado closed federal SBIR/STTR awards in the last two years, newest first. The funding event is the signal — small companies grow right after the award lands.

OCTAVE PHOTONICS LLC

LOUISVILLE, CO · 6 employees

Terabit-Per-Second Integrated Photonic Transceiver for Reduced Optical-Link Power (TIPTOP)

Department of Defense · National Aeronautics and Space Administration · Phase Phase I

$733kacross 4 awardsfunded 2025-12-10Company site →

DEFENSE UNICORNS, INC.

COLORADO SPRINGS, CO · 225 employees

Comprehensive Risk Analysis of Open Source Software_Defense Unicorns

Department of Defense · Phase Phase I/Phase II

$6.4Macross 4 awardsfunded 2025-11-04Company site →

TDA RESEARCH, INC.

GOLDEN, CO · 125 employees

Corrosion and wear resistant coating for rotary engine seals and surfaces

Department of Defense · Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II

$17.7Macross 27 awardsfunded 2025-11-03Company site →

AERIS LLC

LOUISVILLE, CO · 28 employees

ML-Based Downscaling for High-Resolution Atmospheric Forecasting

Department of Defense · Phase Phase I

$140kawardedfunded 2025-11-03Company site →

ORBITAL MICRO SYSTEMS, INC. DBA Weather Stream

Boulder, CO · 30 employees

GEMS-PEARL OSVW Retrieval Demonstration

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$4.3Macross 4 awardsfunded 2025-11-03Company site →

ADVANCED ENVIRONMENTAL TECHNOLOGIES LLC

FORT COLLINS, CO · 4 employees · woman-owned

Development of an Alfalfa/Biodigested Lignite/Fungal Bioleaching-based System to Enhance Phytomining of Nickel from Soil

Department of Energy · Phase Phase I/Phase II

$600kacross 2 awardsfunded 2025-10-15Company site →

ICARUS QUANTUM INC

BOULDER, CO · 4 employees

Noise-free Excitation of Semiconductor Quantum Dots

Department of Commerce · National Science Foundation · Phase Phase I/Phase II

$705kacross 2 awardsfunded 2025-10-01Company site →

NCO Technologies LLC

Aurora, CO · 2 employees

SBIR Phase I: Scalable Production of High-Performance Metal-Organic Framework Membranes

Department of Energy · National Science Foundation · Phase Phase I

$505kacross 2 awardsfunded 2025-10-01

Pricing Service, Inc

Boulder, CO · 5 employees

SBIR Phase I: Scalable AI-Enabled Automated Pricing Tool for Service Industries

National Science Foundation · Phase Phase I

$300kawardedfunded 2025-10-01Company site →

ALBEDO SPACE CORP.

BROOMFIELD, CO · 52 employees

Novel Automated Physical Damage Detector Leveraging 10 cm Visible with 2 m Thermal Imagery

Department of Defense · Phase Phase I

$100kawardedfunded 2025-09-30Company site →

APPLIED RESEARCH TEAM INC

DENVER, CO · 3 employees · woman-owned

Continuous Snow Monitoring for Improved Water Supply Management

National Aeronautics and Space Administration · Phase Phase I/Phase II

$1.1Macross 2 awardsfunded 2025-09-30Company site →

RAVEN SPACE SYSTEMS, INC.

Broomfield, CO · 7 employees

3D Printing of High-temperature Composites

Department of Defense · Phase Phase II

$2.7Macross 2 awardsfunded 2025-09-23Company site →

VESCENT TECHNOLOGIES INC.

GOLDEN, CO · 58 employees

Photonic Reconfigurable Optical-frequency-comb-based Microwave sensor for Intelligence and Signals Exploitation (PROMISE)

Department of Defense · Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II

$1.6Macross 5 awardsfunded 2025-09-22Company site →

PICKNIK INC.

Boulder, CO · 24 employees

Space ROS Improvements for Space Flight

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$2.2Macross 5 awardsfunded 2025-09-19Company site →

Pegasus Aerospace, Inc.

Golden, CO · 5 employees

Air Launch Balloon System

Department of Defense · Phase Phase II

$1.2Mawardedfunded 2025-09-18

Pearl Scientific

Denver, CO · 2 employees · woman-owned

The development of humanized SEMA7A-antagonist mAbs for the therapeutic treatment of breast cancer

Department of Health and Human Services · Phase Phase I

$393kawardedfunded 2025-09-18Company site →

BLUESHIFT LLC

BROOMFIELD, CO · 10 employees

Physics-Based Continuum Numerical Framework for Large-Scale Lunar Terramechanics Applications

National Aeronautics and Space Administration · Phase Phase I

$313kacross 2 awardsfunded 2025-09-18Company site →

Quindar Inc.

Arvada, CO · 56 employees

Intelligent High-Side Mission Management for Proliferated Space Operations

Department of Defense · Phase Phase I/Phase II

$3.1Macross 3 awardsfunded 2025-09-18

SPORIAN MICROSYSTEMS, INC

LAFAYETTE, CO · 19 employees

Autonomous Real Time, Multi Species Monitoring System for In-line Commodity Purity Analysis

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$3.5Macross 6 awardsfunded 2025-09-17Company site →

OPTIMIZATION TECHNOLOGIES, INC.

BOULDER, CO · 25 employees

Benchmarking Simulations for Missile Defense System Analysis

Department of Defense · Phase Phase I/Phase II

$2.3Macross 2 awardsfunded 2025-09-17Company site →

BIG METAL ADDITIVE LLC

DENVER, CO · 22 employees

Additive Manufacturing for Big Navy Parts

Department of Defense · Phase Phase I/Phase II

$2.1Macross 2 awardsfunded 2025-09-17Company site →

Vesicle Therapeutics Inc.

Niwot, CO · 2 employees

Targeting STAT3 with Novel Thiomorpholino Antisense Oligonucleotides for Cancer Therapy

Department of Health and Human Services · Phase Phase I

$400kawardedfunded 2025-09-16

BURST DIAGNOSTICS INC

FORT COLLINS, CO · 2 employees

Multiplexed Hormone Test for Personalizing Menopause Treatment

Department of Health and Human Services · Phase Phase I

$301kawardedfunded 2025-09-15

Allander Biotechnologies

AURORA, CO · 3 employees · woman-owned

First-in-human clinical trial of proprietary oral gel to treat radiation-induced oral mucositis in cancer patients

Department of Health and Human Services · Phase Phase II

$1.2Mawardedfunded 2025-09-15

KLEIN BUENDEL, INC.

GOLDEN, CO · 27 employees · woman-owned

Hybrid Delivery to Increase Access and Sustainability: Evaluating ezParent Implementation

Department of Health and Human Services · Phase Phase I/Phase II

$1.0Macross 2 awardsfunded 2025-09-15Company site →

THINKORBITAL INC.

BOULDER, CO · 13 employees

ThinkPlatform: Modular In-Space Construction Powered by ThinkToolkit

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$5.0Macross 5 awardsfunded 2025-09-15Company site →

VITRO3D INC.

BOULDER, CO · 5 employees

SBIR Phase II: Parallax Manufacturing for Next Generation Electronic Connectors

National Science Foundation · Phase Phase II

$1.2Mawardedfunded 2025-09-15Company site →

Volta Space Technologies U.S., LLC

Broomfield, CO · 14 employees

System with Ultra-staBle Magnetic Inertial Control Regulation for Orbital beaming (SUBMICRO)

National Aeronautics and Space Administration · Phase Phase I

$148kawardedfunded 2025-09-15Company site →

TECH-X CORPORATION

Boulder, CO · 16 employees

Numerical modeling of linear and non-linear plasma waves due to antennas immersed in a space plasma

Department of Defense · Phase Phase I

$180kawardedfunded 2025-09-15Company site →

RHEUMAGEN, INC.

DENVER, CO · 2 employees

HLA Gene Editing in the Treatment of Rheumatoid Arthritis

Department of Health and Human Services · Phase Phase I

$307kawardedfunded 2025-09-15

REACTION SYSTEMS, INC.

GOLDEN, CO · 10 employees

Regenerable CO2 Control System for Self Contained Breathing Apparatus (RCCS for SCBA)

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$1.7Macross 3 awardsfunded 2025-09-13Company site →

Kioga Inc.

Erie, CO · 3 employees

Evaluation of a novel soil-derived Mycobacterium as a nutritional supplement to promote stress resilience

Department of Health and Human Services · Phase Phase II

$335kawardedfunded 2025-09-12

Ursa Major Technologies, Inc.

Berthoud, CO · 280 employees

Main Injector Development for Reusable Methane Rocket Engine

Department of Defense · Phase Phase II

$1.9Mawardedfunded 2025-09-12Company site →

EDIFY TECHNOLOGIES, INC

DENVER, CO · 6 employees

MusiQuest: Music Education Modules For K-2 Students

Department of Education · Department of Health and Human Services · Phase Phase II

$2.0Macross 2 awardsfunded 2025-09-12Company site →

AGILE RF SYSTEMS LLC

BERTHOUD, CO · 9 employees · woman-owned

Portable Weather Radar Maturation with Advanced AESA

Department of Defense · National Aeronautics and Space Administration · Phase Phase II

$5.2Macross 2 awardsfunded 2025-09-11Company site →

OPTERUS RESEARCH AND DEVELOPMENT, INC

LOVELAND, CO · 18 employees

Modular Operations, Resource, & Power Hub (MORPH)

National Aeronautics and Space Administration · Phase Phase I/Phase II

$1.3Macross 4 awardsfunded 2025-09-11Company site →

ELEMENTUM 3D, INC.

ERIE, CO · 38 employees

GRX-810 for Cold Spray Additive Manufacturing, Coating, and Repair

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$1.4Macross 3 awardsfunded 2025-09-11Company site →

ADVANCED SPACE LLC

WESTMINSTER, CO · 104 employees

Lunar Sentinel

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$5.0Macross 6 awardsfunded 2025-09-10Company site →

BLACK SWIFT TECHNOLOGIES LLC

BOULDER, CO · 12 employees

Adaptive and Secure Autonomy for UAS: A Modular Approach to Flight Control, Machine Learning Integration, and Multi-Vehicle Coordination

Department of Defense · National Aeronautics and Space Administration · Phase Phase I

$446kacross 3 awardsfunded 2025-09-09Company site →

FLUOROFINDER LLC

BROOMFIELD, CO · 8 employees

Streamlining Microscopy Assay Development: A Comprehensive Workflow Solution for Enhanced Reproducibility and Efficiency

Department of Health and Human Services · Phase Phase I

$705kacross 2 awardsfunded 2025-09-04Company site →

Precision Materials Engineering LLC

CASTLE ROCK, CO · 5 employees · woman-owned

Novel Single-Phase Refractory-Metal Alloy for Reusable Thermal Protection Systems

Department of Energy · National Aeronautics and Space Administration · Phase Phase I

$362kacross 2 awardsfunded 2025-09-04

McMurchie Engineering LLC

Kittredge, CO · 3 employees · woman-owned

Monolithic Highly Porous Aluminum Deployable Micrometeoroid Impact Shields

National Aeronautics and Space Administration · Phase Phase I

$150kawardedfunded 2025-09-03

Chi3 Optics LLC

Boulder, CO · 4 employees

A Space-Qualified Optical Frequency Comb with Integrated Nanophotonic Heterodyne Module

National Aeronautics and Space Administration · Phase Phase I

$150kawardedfunded 2025-09-02Company site →

OsmoPure Technologies, Inc

BOULDER, CO · 7 employees

SBIR Fast-Track: Scaling Up Pressure-Driven Distillation for Ultrapure Water Production

National Aeronautics and Space Administration · National Science Foundation · Phase Phase I/Phase II

$2.4Macross 3 awardsfunded 2025-09-01Company site →

Z BIOTECH, LLC

AURORA, CO · 3 employees

Development and Commercialization of Sialoglycan-Recognizing Probes

Department of Health and Human Services · Phase Phase I

$927kacross 3 awardsfunded 2025-09-01Company site →

RapiCure Solutions, Inc.

Loveland, CO · 8 employees

SBIR Fast-Track: Rapid Repair, Protection, and Reclamation of Key Infrastructure Assets by Frontally Polymerizing Resin System

National Science Foundation · Phase Phase I/Phase II

$1.6Macross 2 awardsfunded 2025-09-01Company site →

OTORO ENERGY INC

BOULDER, CO · 0 employees

SBIR Phase II: Flow Battery Electrolyte Purification: Unlocking 24-Hour Storage Potential

National Science Foundation · Phase Phase II

$1.2Mawardedfunded 2025-09-01

CASCADE BIOCATALYSTS INC.

DENVER, CO · 9 employees

SBIR Phase II: Enzyme Stabilization via Immobilization for Advanced Chemical Manufacturing

National Science Foundation · Phase Phase II

$1.3Mawardedfunded 2025-09-01Company site →

MEADOWLARK OPTICS, INC.

FREDERICK, CO · 40 employees

Improving Speed and Cost of Entry for Holographic Optogenetics

Department of Energy · Department of Health and Human Services · Phase Phase II

$2.2Macross 2 awardsfunded 2025-09-01Company site →

Onconaut Therapeutics Inc.

Aurora, CO · 4 employees

CHD1Li Targeted Combinations with Chemotherapy to Address Unmet Needs in Colorectal Cancer Treatment

Department of Health and Human Services · Phase Phase I

$400kawardedfunded 2025-09-01

ROCKYTECH LTD

Boulder, CO · 7 employees · woman-owned

Advanced Polymer Nanocomposites for Lunar Dust Mitigation and Surface Longevity

National Aeronautics and Space Administration · Phase Phase I

$156kawardedfunded 2025-08-29Company site →

DRAFTER INC

DENVER, CO · 6 employees

Drafter - Generative AI for hardware development processes, informed by realities in manufacturing and design

Department of Defense · Phase Phase I

$73kawardedfunded 2025-08-28

FIREFLY MEDICAL INC

FORT COLLINS, CO · 4 employees

State-of-the-Art Mobility Device Promoting Rapid Recovery for Faster Return to Duty and Improved Standard of Care

Department of Defense · Phase Phase I/Phase II

$1.3Macross 2 awardsfunded 2025-08-28Company site →

SkyVision Sciences, LLC

Steamboat Springs, CO · 9 employees

Additive Manufacturing Process for Magnetic Shielding

Department of Energy · National Aeronautics and Space Administration · Phase Phase I

$356kacross 2 awardsfunded 2025-08-28Company site →

PrecisionTerra, Inc.

SUPERIOR, CO · 2 employees · woman-owned

A software-based positioning, navigation, and timing solution for reliable operation in GPS-degraded environments

National Aeronautics and Space Administration · Phase Phase I

$157kawardedfunded 2025-08-27

AGILE SPACE INDUSTRIES, INC.

DURANGO, CO · 110 employees

Agile Thruster Production for Space Superiority

Department of Defense · Phase Phase II

$2.0Mawardedfunded 2025-08-27Company site →

QUEST THERMAL GROUP, LLC

ARVADA, CO · 12 employees

Advanced Cryogenic Insulation with reduced thermal conduction and high performance at low temperatures

National Aeronautics and Space Administration · Phase Phase I

$153kawardedfunded 2025-08-25Company site →

Atolio, Inc.

Denver, CO · 8 employees

AI-Driven Enterprise Search for Secure DevSecOps Environments

Department of Defense · Phase Phase II

$1.2Mawardedfunded 2025-08-25Company site →

orbital mining corporation

Golden, CO · 4 employees

Lunar SCRUB: Lunar Surface Cleaning Robotic Unit with electron-Beam

National Aeronautics and Space Administration · Phase Phase I

$150kawardedfunded 2025-08-25Company site →

EMode, Inc.

Boulder, CO · 3 employees · woman-owned

Quantum Waveguide Infrared Photodetector for Heterodyne Spectroscopy

National Aeronautics and Space Administration · National Science Foundation · Phase Phase I

$455kacross 2 awardsfunded 2025-08-25Company site →

CALIOLA ENGINEERING, LLC

COLORADO SPRINGS, CO · 69 employees · woman-owned

Delivering Waveform Capability at the Speed of Relevance

Department of Defense · Phase Phase I/Phase II

$8.5Macross 8 awardsfunded 2025-08-19Company site →

EMPRISE CONCEPTS, LLC

EVERGREEN, CO · 11 employees

Geohazard Susceptibility and Risk Forecasting Tool for Railroads

Department of Transportation · Phase Phase I

$206kawardedfunded 2025-08-18

URBAN SKY THEORY INC

DENVER, CO · 40 employees

STRATFI

Department of Defense · Phase Phase II

$15.0Mawardedfunded 2025-08-15Company site →

Atomic Research LLC

Colorado Springs, CO · 1 employee

FlightEdge: Real-time, Distributed AI/ML Model Training for Predictive Maintenance

Department of Defense · Phase Phase II

$1.1Mawardedfunded 2025-08-08Company site →

OZNI AI LLC

COLORADO SPRINGS, CO · 1 employee

NEMESIS

Department of Defense · Phase Phase II

$3.8Macross 2 awardsfunded 2025-08-08Company site →

AQWEST, LLC

LARKSPUR, CO · 10 employees

High Energy, Multi-Component, Optical Isolator for 2 Micron Fiber Lasers

Department of Defense · Department of Energy · Phase Phase I/Phase II

$3.1Macross 3 awardsfunded 2025-08-07Company site →

Access Sensor Technologies LLC

Fort Collins, CO · 7 employees

High-Throughput Automated Air Sample Analysis Platform for Exposomics and Precision Environmental Health Research

Department of Health and Human Services · Phase Phase I

$612kacross 2 awardsfunded 2025-08-05Company site →

RoGo Fire LLC

Westminster, CO · 3 employees

GAS on Fire (Guided, Accurate Slurry drops on Fire)

National Aeronautics and Space Administration · Phase Phase II

$899kawardedfunded 2025-08-05Company site →

SOLARIS VACCINES, INC.

FORT COLLINS, CO · 4 employees

A whole-cell inactivated vaccine for improved protection against tuberculosis

Department of Defense · Department of Health and Human Services · Phase Phase I/Phase II

$1.6Macross 2 awardsfunded 2025-08-01Company site →

GENEVA TECHNOLOGIES, INC.

MONUMENT, CO · 42 employees · woman-owned

Logistics Infrastructure and Knowledge from Engineered Transportation Optimization

Department of Defense · Phase Phase I/Phase II

$2.0Macross 2 awardsfunded 2025-08-01

BIOTA INC.

Fort Collins, CO · 4 employees · woman-owned

Bringing PFAS Monitoring Home: An Integrated Magnetic Nanoparticle and Lateral Flow Assay System

Department of Health and Human Services · Phase Phase I

$307kawardedfunded 2025-08-01Company site →

TaeSun

Salida, CO · 3 employees · woman-owned

A comprehensive device integrating fentanyl test strips with sample preparation features for convenient and discreet fentanyl testing in hig

Department of Health and Human Services · Phase Phase I

$305kawardedfunded 2025-08-01Company site →

PARMAN TECH, Inc

Loveland, CO · 3 employees

Development of Advanced Microfluidic Module with Integrated Manifold and Tapered Capillary for Separation of Particles by Optical Forces: Ph

Department of Commerce · Phase Phase I

$107kawardedfunded 2025-08-01Company site →

MANTEL TECHNOLOGIES, INC.

FORT COLLINS, CO · 32 employees

Canine Chem-Bio Protective Garment System

Department of Defense · Phase Phase I

$390kacross 2 awardsfunded 2025-07-31Company site →

LAMBDA METRICS LLC

BOULDER, CO · 2 employees

Serpentine Integrated Grating Spectrometer for Extreme Precision Radial Velocimetry

National Aeronautics and Space Administration · Phase Phase II

$899kawardedfunded 2025-07-30

CLOUDSCI LLC

Fort Collins, CO · 8 employees

Airborne holographic probe for small ice detection

Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II

$1.1Macross 2 awardsfunded 2025-07-30Company site →

DATA FUSION & NEURAL NETWORKS, LLC

ARVADA, CO · 7 employees

Detecting Threats To PWSA Constellation Using AI and Satellite Telemetry Data

Department of Defense · Phase Phase II

$1.9Mawardedfunded 2025-07-25

SKYWARD FEDERAL LLC

COLORADO SPRINGS, CO · 40 employees

Skyward Federal Joint Track Manager Data Synchronization Solution

Department of Defense · Phase Phase I

$139kawardedfunded 2025-07-22Company site →

FIRST RF CORPORATION

BOULDER, CO · 130 employees

N251-001 Directional High Front to Back Ratio Low Frequency Antenna

Department of Defense · Phase Phase I/Phase II

$4.0Macross 4 awardsfunded 2025-07-22Company site →

DARWIN BIOSCIENCES, INC.

BROOMFIELD, CO · 6 employees

Point-of-need screening device for lung cancer in low-resource settings

Department of Health and Human Services · Phase Phase I

$400kawardedfunded 2025-07-17Company site →

INTRACK RADAR TECHNOLOGIES, INC.

COLORADO SPRINGS, CO · 34 employees

InTrack Radar Object Transiting Tracker Proposal

Department of Defense · Phase Phase II

$1.8Mawardedfunded 2025-07-15Company site →

THE GRONSTEDT GROUP INC

DENVER, CO · 25 employees

Battle Rhythm

Department of Defense · Phase Phase I

$280kacross 2 awardsfunded 2025-07-14Company site →

VISTAR ENTERPRISES LLC

BERTHOUD, CO · 1 employee

Advanced Precision Design of Origami Inspired Deployable Metaoptic LiDAR Aperture

National Aeronautics and Space Administration · Phase Phase II

$899kawardedfunded 2025-07-14Company site →

INTELLIGENT PAYLOAD SOLUTIONS, INC.

COLORADO SPRINGS, CO · 11 employees

DataForge: Multi-Domain Synthetic Data Generation

Department of Defense · Phase Phase II

$1.0Mawardedfunded 2025-07-10Company site →

CANOPY AEROSPACE, INC.

LITTLETON, CO · 17 employees

Smart Thermal Protection Systems for Hypersonics

Department of Defense · Phase Phase I/Phase II

$2.1Macross 2 awardsfunded 2025-07-09Company site →

Mallinda Inc.

Denver, CO · 3 employees

Reformable Vitrimer Patches for Composite Repair: Vitripatch

Department of Defense · Phase Phase I

$140kawardedfunded 2025-07-07Company site →

NEXUS WEATHER AND CLIMATE, INC

LONGMONT, CO · 6 employees

Continuous Assimilation Weather Forecasts (CAWF)

Department of Defense · Phase Phase I

$140kawardedfunded 2025-07-07Company site →

HARKIND DYNAMICS LLC

EVERGREEN, CO · 1 employee

Small-Arms Kinetic Defeat Ammunition for Explosive Ordnance Disposal

Department of Defense · Phase Phase I/Phase II

$1.4Macross 2 awardsfunded 2025-07-07

NP TECHNOLOGY LLC

COLORADO SPRINGS, CO · 5 employees · woman-owned

7.62x51 Low Collateral Explosive Ordnance Disposal (EOD) Projectile Ammunition

Department of Defense · Phase Phase I

$135kawardedfunded 2025-07-07Company site →

Electro Magnetic Applications, Inc.

Lakewood, CO · 65 employees

Radiation Tolerant Fiber Optic Communication

Department of Defense · Phase Phase I/Phase II

$3.6Macross 5 awardsfunded 2025-07-03Company site →

THE HYPERSHIELD PARTNERSHIP, LLC

CONIFER, CO · 0 employees

HiFi FTSI

Department of Defense · Phase Phase I

$146kawardedfunded 2025-07-02Company site →

EVITADO USA LLC

Golden, CO · 5 employees

Evitado TACFI

Department of Defense · Phase Phase II

$2.0Mawardedfunded 2025-07-01

Hydronovo, Inc

EDWARDS, CO · 2 employees · woman-owned

Regeneration of radiation-damaged salivary glands using neurogenicstimulation of stem cells

Department of Health and Human Services · Phase Phase II

$1.0Mawardedfunded 2025-07-01

TUSAAR CORP

BROOMFIELD, CO · 6 employees

Scale-Up and Commercialization of Rare Earth Separation from Mining Wastes Using Chromatography

Department of Defense · Phase Phase II

$2.1Mawardedfunded 2025-06-25Company site →

STRATOM, INC.

Louisville, CO · 16 employees

Autonomous Unmanned Surface Vehicle Fueling at Sea

Department of Defense · Phase Phase I

$140kawardedfunded 2025-06-24Company site →

Intero Biosystems Inc.

Aurora, CO · 5 employees

A Novel Multi-Lineage Human Intestinal Organoid Screening Platform for Drug Discovery and Preclinical Testing

Department of Health and Human Services · Phase Phase I

$350kawardedfunded 2025-06-20Company site →

KATHAROS, INC.

DENVER, CO · 2 employees · woman-owned

Novel Extracorporeal Technology for Kidney Disease

Department of Health and Human Services · Phase Phase I

$350kawardedfunded 2025-06-20

PROPULSION RESEARCH LLC

COLORADO SPRINGS, CO · 2 employees

A Proposal to Synthesize Modified Churchanes for Mixtures with JP-10 to Enhance Energy Density

Department of Defense · Phase Phase I

$140kawardedfunded 2025-06-18

ADA TECHNOLOGIES LLC

ENGLEWOOD, CO · 11 employees

Safe, Wide-temperature Range, Long Life 0V Storage-capable Batteries for Army Ground Vehicle Applications

Department of Defense · Phase Phase II

$5.7Macross 3 awardsfunded 2025-06-17Company site →

LaminarEdge Aerospace LLC

Colorado Springs, CO · 7 employees · woman-owned

High-Capacity Internal Balance?

Department of Defense · Phase Phase I

$140kawardedfunded 2025-06-09Company site →

MOTHER'S MILK IS BEST, INC.

FORT COLLINS, CO · 2 employees · woman-owned

Point of Care maternal milk concentration device optimizing neonatal growth with targeted nutrition support: Establishing clinical evidence

Department of Health and Human Services · Phase Phase II

$1.2Mawardedfunded 2025-06-05Company site →

Robotic Construction Technologies, Inc.

DENVER, CO · 8 employees

Robotic Construction of Critical USAF Infrastructure

Department of Defense · Phase Phase II

$1.3Mawardedfunded 2025-05-29Company site →

ALESIA ENGINEERING LLC

COLORADO SPRINGS, CO · 2 employees · woman-owned

Insight for Evaluating Risks and Impacts to Space Systems and Services

Department of Defense · Phase Phase II

$1.9Mawardedfunded 2025-05-28Company site →

ENGAGE MOBILIZE INC

DENVER, CO · 26 employees

No Fuel, No Fight: Enabling Global Reach and Global Strike Through Fuel Transparency, Optimization, and Readiness

Department of Defense · Phase Phase II

$1.2Mawardedfunded 2025-05-23Company site →

NANOPLASMONICS LLC

COLORADO SPRINGS, CO · 2 employees

SBIR Phase I: Plasmonically Enhanced Molecular Imprinted Polymers for Toxins Detection

National Science Foundation · Phase Phase I

$305kawardedfunded 2025-05-23

CISLUNAR INDUSTRIES USA INC

LOVELAND, CO · 19 employees

Interoperable Modular Power Unit for Lightweight and Scalable Electric Propulsion (IMPULSE) - Sustained Space Maneuver (SSM) - SF243-D018

Department of Defense · Phase Phase II

$1.9Mawardedfunded 2025-05-23Company site →

PLASMA CONTROLS, LLC

FORT COLLINS, CO · 5 employees

High Current Electron Source for Multimode Electric Propulsion Systems

Department of Defense · Phase Phase II

$1.9Mawardedfunded 2025-05-23

Mana Battery, Inc.

Denver, CO · 15 employees

SBIR Phase I: Electrolyte and Interphase Design for Stable, Safe, and Low-Cost Sodium Batteries

Department of Defense · National Science Foundation · Phase Phase I

$525kacross 2 awardsfunded 2025-05-22Company site →

HYSA FILLERS L.L.C.

GOLDEN, CO · 3 employees

SBIR Phase II: Multi-Principal Element Alloy Fillers for Cost-Effectiveness and Toughness Enhancement in Brazing of Turbine Engine Component

National Science Foundation · Phase Phase II

$1.2Mawardedfunded 2025-05-21

Liquen Technologies, Inc.

GOLDEN, CO · 2 employees

Supercritical Fluid Cartridges for Calibration of Air Pollution Sensors

Department of Health and Human Services · Phase Phase I

$306kawardedfunded 2025-05-21

TB2 AEROSPACE

BRECKENRIDGE, CO · 4 employees

Multi-Purpose Long Endurance UAV Payload Pod for Austere Operations

Department of Defense · Phase Phase II

$1.8Mawardedfunded 2025-05-20Company site →

MATRIX DESIGN GROUP INC

COLORADO SPRINGS, CO · 215 employees

Dormitory Readiness Tool (DRT)

Department of Defense · Phase Phase II

$1.2Mawardedfunded 2025-05-16Company site →

GELASTOMERICS LLC

FORT COLLINS, CO · 3 employees

SBIR Phase I: Bringing Intrinsic Lubricity to the Medical Elastomer Market

National Science Foundation · Phase Phase I

$305kawardedfunded 2025-04-30

ADVANCED CONDUCTOR TECHNOLOGIES LLC

BOULDER, CO · 6 employees

High field CORC solenoids

Department of Energy · Phase Phase I/Phase II

$1.3Macross 2 awardsfunded 2025-04-14Company site →

DOUBLE HELIX OPTICS, INC.

BOULDER, CO · 8 employees

High-resolution extended-depth phase-engineered objectives to accelerate spatial 'omics R&D through computational optics

Department of Health and Human Services · Phase Phase II

$1.1Mawardedfunded 2025-04-04

COLDQUANTA, INC.

BOULDER, CO · 165 employees

SAPIENT

Department of Defense · Phase Phase I/Phase II

$4.1Macross 3 awardsfunded 2025-03-26Company site →

FORGE NANO, INC.

THORNTON, CO · 5 employees

Atomic Layer Deposition-Enabled, Silicon-Based, Fast-Charging Lithium-Ion Cells

Department of Defense · Phase Phase I

$204kawardedfunded 2025-03-14Company site →

IMPRESSIO INC

DENVER, CO · 10 employees

Multi-material 3D Printing Complex Anatomical Structures with a Biomimetic Material for Enhanced Military Medical Training

Department of Defense · Phase Phase I

$250kawardedfunded 2025-02-21Company site →

RADIASOFT LLC

BOULDER, CO · 10 employees

Cross-cutting Simulations with Uncertainty for Fusion Applications

Department of Energy · Phase Phase I

$413kacross 2 awardsfunded 2025-02-18Company site →

KAPTEYN-MURNANE LABORATORIES, INC

BOULDER, CO · 13 employees

New materials for ultrafast laser technology at 2 µm wavelength

Department of Energy · Phase Phase I

$200kawardedfunded 2025-02-18Company site →

TRUENANO, INC.

BROOMFIELD, CO · 2 employees

Fast ANd Trustwordy AI-powered growth of Thick SiC epi (FANTATSIC)

Department of Defense · Phase Phase I

$96kawardedfunded 2025-02-01

ASTRA ULTRA LLC

LITTLETON, CO · 4 employees

Deriving Satellite Maneuver Intent from Orbital Data

Department of Defense · Phase Phase I

$180kawardedfunded 2025-01-31Company site →

FieldLine Industries Inc

Louisville, CO · 8 employees

Standoff Detection of Hidden Objects using Tensor Gradiometers (SHOT)

Department of Defense · Phase Phase I

$204kawardedfunded 2025-01-27Company site →

Curable Composites, Inc.

Windsor, CO · 6 employees

Field-deployable composite manufacturing for rapid, automated production of modular UAS

Department of Defense · Phase Phase I

$75kawardedfunded 2025-01-14Company site →

QI PATH LLC

BOULDER, CO · 3 employees

Proactive Risk Management Platform to Mitigate Aviation Mishaps

Department of Defense · Phase Phase I

$110kawardedfunded 2025-01-14Company site →

BLUE CUBED LLC

LONGMONT, CO · 3 employees

Development of a low SWaP SDA compatible Optical Communications Terminal (OCT)

Department of Defense · Phase Phase I

$180kawardedfunded 2025-01-08

INTELLIGENT IMAGING INNOVATIONS, INC.

DENVER, CO

High bandwidth all-optical electrophysiology

Department of Health and Human Services · Phase Phase I

$505kawardedfunded 2025-01-01

Steadi Systems, LLC

EVERGREEN, CO · 1 employee · woman-owned

SBIR Phase I: Steadi-scores: Translating Balance Science into Clinical Action for Proactive Balance Training

National Science Foundation · Phase Phase I

$305kawardedfunded 2024-12-23Company site →

PAGE Technologies, Inc

Boulder, CO · 5 employees

Low-cost, handheld sensors for measuring environmental nitrates

Environmental Protection Agency · Phase Phase I

$100kawardedfunded 2024-12-16Company site →

HUMLA LLC

BOULDER, CO · 3 employees

High Integrity Position, Navigation, and Time (PNT) and Threat Localization within the Android Operating System

Department of Defense · Phase Phase II

$1.8Mawardedfunded 2024-12-12

ZEPHR.XYZ INC.

LOUISVILLE, CO · 6 employees

An Ad Hoc Networked System for the Real Time Detection, Classification and Localization of Jamming/Spoofing

Department of Defense · Phase Phase II

$1.7Mawardedfunded 2024-12-09Company site →

Global Weather & Climate Solutions, Inc.

GOLDEN, CO · 22 employees

Solving the SBEM Space Weather gaps via dense, global, low latency, GNSS RO electron density, scintillation , energetic charged particle, an

Department of Defense · Phase Phase II

$3.0Mawardedfunded 2024-12-03Company site →

BOULDER ENVIRONMENTAL SCIENCES AND TECHNOLOGY, LLC

BOULDER, CO · 8 employees

Millimeter wave hyperspectral radiometer receivers for next generation SBEM systems

Department of Defense · Phase Phase II

$3.0Mawardedfunded 2024-12-03Company site →

Coruna Medical LLC

LONGMONT, CO · 7 employees · woman-owned

A Supersaturated Oxygen Emulsion for the Topical Treatment of Ocular Trauma

Department of Defense · Phase Phase II

$2.2Mawardedfunded 2024-12-02Company site →

STILMAN ADVANCED STRATEGIES, LLC

DENVER, CO · 25 employees

LG-based Explainable AI to Enable Realistic Theater-level Naval Wargaming

Department of Defense · Phase Phase I/Phase II

$406kacross 2 awardsfunded 2024-11-13Company site →

NUMERICA CORPORATION

FORT COLLINS, CO · 80 employees

Meshed Radar Network Architecture for Expeditionary Air Traffic Control

Department of Defense · Phase Phase II

$1.8Mawardedfunded 2024-11-06Company site →

W9ER ENGINEERING INC

MONUMENT, CO · 1 employee

ProJector; High Efficiency Rotors for High Speed VTOL

Department of Defense · Phase Phase II

$1.8Mawardedfunded 2024-10-23

APPLIED SONICS INC

DENVER, CO · 4 employees

Production of nano and coarse nitramines using in-situ sensors and AI/ML crystallization control

Department of Defense · Phase Phase II

$2.0Mawardedfunded 2024-10-22

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