Recently funded science companies in California
643 companies in California closed federal SBIR/STTR awards in the last two years, newest first. The funding event is the signal — small companies grow right after the award lands.
OBLATE OPTICS INC
SAN DIEGO, CA · 2 employees
“Inverse-designed lightweight, planar focus lenses for Vis to LWIR hyperspectral imaging”
Department of Defense · Phase Phase I/Phase II
INTELLISENSE SYSTEMS INC
TORRANCE, CA · 140 employees
“Tethered Robot for Coating Application and Inspection”
Department of Defense · Department of Homeland Security · National Aeronautics and Space Administration · Phase Phase I/Phase II
AIMDYN, INC.
SANTA BARBARA, CA · 22 employees · woman-owned
“Koopman Operator-Based Rapid Adjudication of Federated COA's (KOBRA)”
Department of Defense · Phase Phase II
SPECTRAL LABS INCORPORATED
SAN DIEGO, CA · 25 employees
“Advanced Wearable Integration and Synchronization Hub (AWISH)”
Department of Defense · Department of Health and Human Services · Phase Phase I/Phase II
TOYON RESEARCH CORPORATION
GOLETA, CA · 275 employees
“Advanced Modeling and Evaluation of Air Combat Autonomy”
Department of Defense · Department of Homeland Security · Phase Phase I/Phase II
LINEAJE INC.
SARATOGA, CA · 30 employees
“Trusted OSS Analysis and TTP Automation for Secure Software Enclaves”
Department of Defense · Phase Phase I/Phase II
MACHINA COGNITA TECHNOLOGIES, INC.
Carlsbad, CA · 23 employees
“Natural-language Ontologies for battlespace Visualizations and Analytics (NOVA)”
Department of Defense · Phase Phase I/Phase II
THOUGHTFORGE INC.
BERKELEY, CA · 5 employees
“SLITHER: Snake-Like Inspection Technology for Hazardous and Enclosed Regions”
Department of Defense · Phase Phase II
PERCEPTRONICS SOLUTIONS, INC
SHERMAN OAKS, CA · 35 employees
“Automated Intelligence Preparation of the Battlespace from Open-Source Information (AutoIPB)”
Department of Defense · Phase Phase I/Phase II
DATASHAPES, INC.
SAN RAFAEL, CA · 3 employees
“Modular, Optimized Real-time Processing Harness for Edge-Unit Schedulers (MORPHEUS)”
Department of Defense · Phase Phase I
INFERLINK CORP
EL SEGUNDO, CA · 24 employees
“GENESIS: Generative AI for Educational Systems and Instructional Support”
Department of Defense · Phase Phase I/Phase II
Fenix Research Corporation
Palo Alto, CA · 6 employees
“Off-Axis Laser Detector”
Department of Defense · Phase Phase I
ATAC
SANTA CLARA, CA · 63 employees
“High-Resolution Environmental Forecasting Through Advanced ML Downscaling Techniques”
Department of Defense · Phase Phase I
ALPHASTAR TECHNOLOGY SOLUTIONS
IRVINE, CA · 12 employees · woman-owned
“A Hybrid Digital Twin Framework for Modeling Machine Process Parameters for Automated Fiber Placement-based Manufacturing of Composite Struc”
Department of Defense · Phase Phase I
STOTTLER HENKE ASSOCIATES, INC
SAN MATEO, CA · 60 employees
“Text-and-Image-Conditioned content GENeration (TICGEN)”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
LUCIDEAN, INC
GOLETA, CA · 8 employees
“Fiber-optic Avionic Low-SWaP-C Coherent Optical Network (FALCON)”
Department of Defense · Phase Phase I/Phase II
FANTASTIC DATA LLC
SAN FRANCISCO, CA · 2 employees
“Intelligent Radio Access Network for Beyond 5G Resilient Tactical Networks”
Department of Defense · Phase Phase I
AMERICAN LITHIUM ENERGY CORP.
Vista, CA · 70 employees
“Development of Safe, Robust, Sodium-Ion Battery for Naval Aviation Using Domestically Made Inexpensive Raw Materials”
Department of Defense · Phase Phase I/Phase II
SYSTEMS TECHNOLOGY, INC
HAWTHORNE, CA · 26 employees
“State and Trajectory Optimization for Real-time Range Extension (STORRE)”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I
NEXTGEN AERONAUTICS, INC.
TORRANCE, CA · 18 employees
“Optimized Novel Multifunctional Composite Sandwich Structures”
Department of Defense · Phase Phase I/Phase II
DSTAR COMMUNICATIONS
WOODLAND HILLS, CA · 2 employees
“Multimode Bragg Grating Multiplexer (MBG MUX)”
Department of Defense · Phase Phase I
M4 ENGINEERING, INC.
LONG BEACH, CA · 35 employees
“Hypersonic Computational Fluid Dynamics Heat Flux Sub-Models”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
APSIDAL LLC
RIVERSIDE, CA · 6 employees
“Low-Dispersion Ultrahigh-Bandwidth Microstructured Photonic Fibers for Avionics Networks and Sensors”
Department of Defense · Phase Phase II
ABRAM SCIENTIFIC INC
SOUTH SAN FRANCISCO, CA · 4 employees
“CoagCare: Novel Miniaturized Handheld Thromboelastographic Platform for Rapid Assessment of Coagulopathy and Resuscitation Management of War”
Department of Defense · Phase Phase II
TopoLight, Inc.
Berkeley, CA · 2 employees
“SBIR Phase I: High-Power, Surface-Emitting, Single-Mode Laser Chips with Photonics Crystal Cavity Design”
National Science Foundation · Phase Phase I
HIGHRI OPTICS, INC.
OAKLAND, CA · 5 employees · woman-owned
“BINARY PSEUDO RANDOM ARRAY (BPRA) FOR THE ENHANCEMENT OF OPTICAL IMAGERS”
Department of Commerce · National Aeronautics and Space Administration · Phase Phase I/Phase II
COOLAIMATE, INC
PASADENA, CA · 2 employees
“SBIR Phase I: Silicon photonics tunable laser for analyzing energy content of natural gas”
National Science Foundation · Phase Phase I
Cosine Corp.
Stanford, CA · 1 employee
“SBIR Phase I: Electrified Thermochemical Biogas Reforming for Hydrocarbon Fuel Production”
National Science Foundation · Phase Phase I
PeraWatt Energy Inc.
Richmond, CA · 2 employees
“STTR Phase I: Scalable Soft Magnetic Composite for High-Frequency Power Electronics”
National Science Foundation · Phase Phase I
KROKOS BIO INC
DAVIS, CA · 0 employees
“SBIR Phase I: A Method for Domestic Production of Saffron, Utilizing Novel Plant Cell Culture Techniques for Cell Adhesion and Immobilizatio”
National Science Foundation · Phase Phase I
YOLO IMMUNE INC
SAN CARLOS, CA · 4 employees
“SBIR Phase I: Novel Immuno-therapy for Specific Depletion of IgG4 Subtype of Autoantibodies”
National Science Foundation · Phase Phase I
Sensate Robotics Inc.
LOS ANGELES, CA · 3 employees
“SBIR Phase I: Tactile-enabled Robotic Quality Control Cell”
National Aeronautics and Space Administration · National Science Foundation · Phase Phase I
Sorcerer Corporation
San Francisco, CA · 3 employees
“SBIR Phase I: Constellation of Small, High-Altitude Balloons for Atmospheric Data Collection”
National Science Foundation · Phase Phase I
VELLEX COMPUTING INC
SAN LUIS OBISPO, CA · 6 employees
“SBIR Phase I: An Analog Hardware Accelerator for Power Systems Feasibility Studies”
National Science Foundation · Phase Phase I
OBJECTSECURITY LLC
SAN DIEGO, CA · 12 employees
“Operational Technology Artificial Intelligence - NIST Compliance Tool (OTAI-NCT)”
Department of Commerce · Department of Defense · Phase Phase I/Phase II
Toro Bio, inc.
Redwood city, CA · 1 employee
“SBIR Phase I: Automated System for Point of Care Manufacture of Tumor Infiltrating Lymphocytes Cell Therapies”
National Science Foundation · Phase Phase I
Infinion Technology, Inc.
Stanford, CA · 2 employees
“STTR Phase I: Improving the reliability of the United States' energy grid by predicting transformer failures”
National Science Foundation · Phase Phase I
Yona Care
San Francisco, CA · 1 employee · woman-owned
“SBIR Phase I: Novel Gynecological Speculum Instrument for Decreased Patient Pain and Enhanced Provider Functionality”
Department of Health and Human Services · National Science Foundation · Phase Phase I
Folde' Inc.
Pleasanton, CA · 11 employees
“SBIR Phase I: A Novel Device for Difficult Urethral Catheterization”
National Science Foundation · Phase Phase I
Electroflow Technologies, Inc.
BURLINGAME, CA · 8 employees
“SBIR Phase I: Assessing and Improving Membrane Stability to Enable Sustainable Lithium Chemical Production”
National Science Foundation · Phase Phase I
RECON RF, INC.
SAN DIEGO, CA · 15 employees
“Advanced Semiconductor Production of Next-Gen X-Band SSPAs for USAF Radar, EW, & Comms”
Department of Defense · Department of Energy · Phase Phase II
ATA ENGINEERING, INC.
SAN DIEGO, CA · 232 employees
“A Machine Learning-Accelerated Framework for Lethality Assessment of Directed Energy Engagements of Hypersonic Threats”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
SEACOAST SCIENCE, INC.
CARLSBAD, CA · 9 employees
“Auto-calibrating, Air Quality Monitoring System”
Department of Health and Human Services · Phase Phase II
VECTOR ATOMIC INC
PLEASANTON, CA · 69 employees
“Iodine Clock with Acceleration- and Radiation-tolerance for Use in Space (ICARUS)”
Department of Defense · Phase Phase II
CHROMOLOGIC LLC
MONROVIA, CA · 35 employees
“Wearable Heat Related Injury Risk Analysis (WHERA) system Resubmission”
Department of Defense · Department of Health and Human Services · Phase Phase I/Phase II
UMBRA LAB, INC
SANTA BARBARA, CA · 135 employees
“CRAZY TRAIN”
Department of Defense · Phase Phase II
Molecular Instruments, Inc.
Los Angeles, CA · 35 employees
“Advancing Probe Technology for Ultrasensitive RNA Imaging via Hybridization Chain Reaction”
Department of Health and Human Services · Phase Phase I
XR NAVIGATION INC
GILROY, CA · 4 employees
“Developing and Evaluating Visual, Auditory, and Tactile and Text Digital Thematic Map Viewer to Provide Blind and Low Vision Individuals Ful”
Department of Health and Human Services · Phase Phase II
Kouros Sariri
Huntington Beach, CA · 34 employees
“-200°C Rad hard Cold Capable Thermally multiplexed controller”
National Aeronautics and Space Administration · Phase Phase I
METROLASER, INCORPORATED
LAGUNA HILLS, CA · 14 employees
“Stand-off Detection of Xenon Spin Polarization by Radar REMPI”
Department of Defense · Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II
CYAN SYSTEMS, INC.
Santa Barbara, CA · 10 employees
“High Dynamic Range Broadband Adaptive Sensor System”
Department of Defense · Phase Phase II
NeoVascularX, Inc.
PALO ALTO, CA · 1 employee
“Topical Ophthalmic Treatment for Neovascular Age-related Macular Degeneration (nAMD)”
Department of Health and Human Services · Phase Phase I
ATOMBEAM TECHNOLOGIES INC.
MORAGA, CA · 7 employees
“Effective Compaction of Satellite Transmission to Maximize Bandwidth and Data Security”
Department of Defense · Phase Phase II
INTERLINK ELECTRONICS, INC
IRVINE, CA · 82 employees
“Innovative Amperometric Gas Sensors for Monitoring Post-Harvest Food Quality and Safety”
Department of Health and Human Services · National Aeronautics and Space Administration · Phase Phase I
OPTO-KNOWLEDGE SYSTEMS INC
TORRANCE, CA · 66 employees
“Optical probe for static pressure measurements in vitiated flows for ground test facilities”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
SYMPLECTIC ENGINEERING CORP
BERKELEY, CA · 1 employee
“High Temperature Fracture”
Department of Defense · Phase Phase II
THINKOM SOLUTIONS, INC.
HAWTHORNE, CA · 178 employees
“Transportable, Flexible, Digital Array Ground Station”
Department of Defense · Phase Phase II
T3W Business Solutions, Inc.
San Diego, CA · 140 employees · woman-owned
“MedScribe Defense - Generative Artificial Intelligence (GenAI) Ambient Medical Scribe Supporting Air Force Medical Readiness Exams and Scree”
Department of Defense · Phase Phase II
OPAL AI INC
LOS ANGELES, CA · 8 employees
“FireVision: An AI-Powered Decision-Support Platform Leveraging NASA Earth Science Data for Wildfire Risk, Mitigation, and Response”
Department of Transportation · National Aeronautics and Space Administration · Phase Phase I/Phase II
Contextual AI, Inc.
Mountain View, CA · 32 employees
“RAG 2.0: Gen AI in Advanced Supply Chain Analytics”
Department of Defense · Phase Phase I
RADIABEAM SYSTEMS, LLC
SANTA MONICA, CA · 12 employees
“Multi-beam accelerator system for mobile food irradiation applications”
Department of Energy · Phase Phase I
EYSZ, INC.
BERKELEY, CA · 1 employee · woman-owned
“Detecting Absence Seizures Using Hyperventilation In a Home Environment”
Department of Health and Human Services · Phase Phase I
WAVEFRONT TECHNOLOGY, INC
PARAMOUNT, CA · 35 employees
“Diamond Turning High Aspect Ratio Mandrels for X-ray Mirror Manufacturing”
National Aeronautics and Space Administration · Phase Phase I
DER SECURITY CORP
SCOTTS VALLEY, CA · 9 employees
“UNsupervised Learning for DER (UNDER): Detecting Power System Attacks Using Machine Learning and Digital Twins”
Department of Energy · Phase Phase I
PHASE III PHYSICS LLC
LOS ANGELES, CA · 6 employees
“A Spiking Neuromorphic Analytics Platform (SNAP) for Photomultiplier Signal Processing”
Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II
TREX ENTERPRISES CORPORATION
EL CAJON, CA · 19 employees
“Metalens Solar Compass (MLSC)”
Department of Defense · Phase Phase II
Syntr Health Technologies, Inc
Irvine, CA · 3 employees
“Device Automation of an FDA-cleared CD-Microfluidic Platform for Rapid Tissue Microsizing”
Department of Health and Human Services · Phase Phase I/Phase II
RANGEVIEW INC.
EL SEGUNDO, CA · 8 employees
“Advanced Digital Investment Casting Technology for High-Precision, Low-Cost Turbine Components”
Department of Defense · Phase Phase II
OPTERRO, INC.
Milpitas, CA · 10 employees
“Robust Highly-Multiplexed Fiber Optic Sensor Array for Cryogenic Fluid Management”
National Aeronautics and Space Administration · Phase Phase I
KARAGOZIAN & CASE, INC.
Glendale, CA · 47 employees
“BDAM: A Blast Dose Accumulation Methodology for Heavy Weapon Firing in Actual Combat Scenarios”
Department of Defense · Phase Phase I
AnySignal, Inc.
El Segundo, CA · 8 employees
“RAIDEN: A Resilient, Agile, and Interference-Defiant Network for Secure MILSATCOM”
Department of Defense · Phase Phase II
OPEN SESAME MEDIA, INC
MARINA DEL REY, CA · 12 employees
“SyncPath - Ultra low-latency resilient multipath communication protocol in contested environments over MILSATCOM only and hybrid SATCOM arch”
Department of Defense · Phase Phase II
CAMBRIDGE TERAHERTZ INC
Santa Clara, CA · 8 employees
“Sub-THz Reflectarrays: An Alternative Architecture for Enhanced Array Scaling with 3D Heterogeneous Integration for DoD ELGAR Use Cases”
Department of Defense · National Science Foundation · Phase Phase II
EITR BIOLOGICS, INC.
SAN DIEGO, CA · 2 employees
“Multidimensional antibody engineering to enhance the potency and breadth of a betacoronavirus medical countermeasure”
Department of Health and Human Services · Phase Phase II
PYKA INC.
Alameda, CA · 69 employees
“Airdrop-Capable Hybrid Group 4 UAS for Contested Logistics: Enabling ACE for the DAF”
Department of Defense · Phase Phase II
FIRESTORM LABS, INC.
SAN DIEGO, CA · 112 employees
“FIRESTORM EXPEDITIONAIRY MANUFACTURING CELL (xCell) AND MANUFACTURED HARDWARE”
Department of Defense · Phase Phase I/Phase II
SHASQI, INC.
SAN FRANCISCO, CA · 4 employees
“CEACAM5-targeted activation of potent chemotherapeutics via bioorthogonal click chemistry”
Department of Health and Human Services · Phase Phase II
MAINSQUARE CO
SAN FRANCISCO, CA · 2 employees · woman-owned
“Engagement and clinical impact of the Teleo virtual therapy platform in clinical settings”
Department of Health and Human Services · Phase Phase II
VENA VITALS INC
IRVINE, CA · 2 employees · woman-owned
“Continuous Non-Invasive Blood Pressure during Sleep as a Cardiovascular Biomarker”
Department of Health and Human Services · Phase Phase I
MAPP BIOPHARMACEUTICAL, INC.
SAN DIEGO, CA · 70 employees
“Development of highly potent human monoclonal for RSV immunoprophylaxis”
Department of Health and Human Services · Phase Phase I/Phase II
METROSAGE LLC
VOLCANO, CA · 2 employees
“Enabling Digital Metrology and Manufacturing Through the Model-Based Enterprise”
Department of Defense · Phase Phase II
DIVERGENT TECHNOLOGIES INC
TORRANCE, CA · 447 employees
“Adaptive Manufacturing to Scale Production and Integration of Third-Party Innovations across the Defense Industrial Base”
Department of Defense · Phase Phase I/Phase II
ANTARES NUCLEAR, INC.
Torrance, CA · 100 employees
“High Temperature Radiator Coating”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
Hop Aero, Inc.
Orange, CA · 6 employees
“ROOK: Rapid Operations Over Kilometers”
Department of Defense · Phase Phase II
PARAMITA THERAPEUTICS, INC.
SAN DIEGO, CA · 5 employees
“Novel multivalent PSMA-targeted taxane-conjugates for bone metastases in prostate cancer”
Department of Health and Human Services · Phase Phase I
MIMYR, LLC
TORRANCE, CA · 8 employees
“Briefing and Onboard Data Enhancement for Pilot Vehicle Interface (BODENPVI)”
Department of Defense · Phase Phase I/Phase II
ORPRO THERAPEUTICS INC
SAN DIEGO, CA · 3 employees
“Engineered Monothiol Thioredoxin for Treatment of Radiation Induced Lung Injury”
Department of Health and Human Services · Phase Phase I
NEONC TECHNOLOGIES INC
LOS ANGELES, CA · 3 employees
“Developing a Clinically Relevant Radiosensitizer for Temozolomide-resistant Gliomas”
Department of Health and Human Services · Phase Phase I/Phase II
DYNOVAS INC
POWAY, CA · 51 employees
“Dynovas Advanced Pressure Resin Transfer Molding (DAP-RTM) for Large Three Dimensional Woven Preforms”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
ARRIS COMPOSITES, INC.
BERKELEY, CA · 40 employees
“Continuous-Fiber & Long-Fiber Thermoplastic Composite Molding for Aerospace Structures”
Department of Defense · Phase Phase II
Exploration Technology Group Corp
San Francisco, CA · 4 employees
“High-Test Peroxide Generation System for Scalable In-Situ Monopropellant Production from Lunar Water and Oxygen”
National Aeronautics and Space Administration · Phase Phase I
ARINNA, INC
South San Francisco, CA · 8 employees
“Extremely power-dense solar for the extremes of space”
National Aeronautics and Space Administration · National Science Foundation · Phase Phase I
OPTO-ATOMICS CORP
SAN PEDRO, CA · 4 employees
“Sodium Excitation Laser for Mesospheric Analysis”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
VIRIDIAN SPACE CORPORATION
EL SEGUNDO, CA · 8 employees
“Resilient VLEO Operations with an Air Scooping Electric Thruster”
Department of Defense · Phase Phase I/Phase II
COSMIC ROBOTICS, INC.
SAN FRANCISCO, CA · 8 employees
“Cosmic-XT, A Truss-Traversing General-Purpose Outfitting Robot”
National Aeronautics and Space Administration · Phase Phase I
EXQUADRUM INC
VICTORVILLE, CA · 73 employees
“ULTRA-VK Exoatmospheric Flight Test”
Department of Defense · Phase Phase I/Phase II
RAREFIED BIOSCIENCES, INC.
SANTA MONICA, CA · 1 employee
“Testing MALT1 inhibitors as a treatment for the rare pediatric inborn error of immunity CARD11 gain of function”
Department of Health and Human Services · Phase Phase I
EMPOWERX, INC.
DEL MAR, CA · 10 employees · woman-owned
“PEP/PrEP via Pharmacist-Prescribing Implementation (PEPPI)”
Department of Health and Human Services · Phase Phase I
SAAZ MICRO, INC.
CAMARILLO, CA · 45 employees
“UNHIDES - Uncover Nimble Hypersonic objects by Imaging in Dual-band Event-based Sensing”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
NOVOMEDIX LLC
SAN DIEGO, CA · 5 employees · woman-owned
“Arthrofibrosis control using small molecule inhibitors of interleukin-11”
Department of Health and Human Services · Phase Phase I/Phase II
Amira Health Inc.
SOUTH SAN FRANCISCO, CA · 4 employees · woman-owned
“Validating Terra, a device for closed-loop hot-flash cooling relief and sleep improvement”
Department of Health and Human Services · Phase Phase I
SINOPIA BIOSCIENCES INC
SAN DIEGO, CA · 4 employees
“Development of a metabolomics enabled AI/ML platform for discovery of new treatments to enhance drug sensitivity in cancer”
Department of Health and Human Services · Phase Phase I
TRL11 INC
Irvine, CA · 20 employees
“MoonCast: Space-Rated Codec for Ultra-Low Delay, True Color Capture Lunar Broadcasting T8.08 Lunar Imagery”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
INTELLIGENT FIBER OPTIC SYSTEMS CORP
Fremont, CA · 22 employees
“Photonically Sensorized Robotic Subsurface Sampling System”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
NEST HEALTH TECH INC.
ALBANY, CA · 9 employees
“CARDIAC CASCADE: Cardiomyopathy and Arrhythmia Risk Dissemination through Innovative Family Sharing”
Department of Health and Human Services · Phase Phase I/Phase II
Translucence Biosystems, Inc.
IRVINE, CA · 10 employees
“Brain-Wide Quantification of Blood-Brain Barrier Penetrating Antibody Therapeutics”
Department of Health and Human Services · Phase Phase II
Panorama Research Incorporated
Sunnyvale, CA · 15 employees
“Novel Therapy for Sarcopenia”
Department of Health and Human Services · Phase Phase I
Storii, Inc.
San Mateo, CA · 14 employees
“Strengthening Bonds: A Telephone Reminiscence Intervention to Reduce Social Isolation and Improve Mental Health in Rural Older Adults”
Department of Health and Human Services · Phase Phase II
JAAN BIOTHERAPEUTICS LLC
SAN DIEGO, CA · 1 employee · woman-owned
“Heart Muscle Regeneration”
Department of Health and Human Services · Phase Phase II
ONE HEALTH STUDIO LLC
San Francisco, CA · 0 employees
“Flourish All: Women's Integrated Stress Reduction for Alzheimer's Risk Prevention Using Digital Tools and Biomarker Monitoring”
Department of Health and Human Services · Phase Phase I
HIDO TECHNOLOGIES, INC
EL DORADO HILLS, CA · 5 employees
“Behavioral Shifts in Dementia Patients Using Novel Pharmacy Home Robotics: A Cost-Effective Approach to Aging in Place”
Department of Health and Human Services · Phase Phase II
Dabble Health
Newark, CA · 1 employee
“Ecological Cognitive Monitoring through AI-Enhanced Personal Photo Activities”
Department of Health and Human Services · Phase Phase I
AIVOCODE, INC.
SAN DIEGO, CA · 3 employees
“Single domain antibody development for improving vascular dysfunction in Alzheimer’s disease”
Department of Health and Human Services · Phase Phase II
CELLSIGHT TECHNOLOGIES, INC.
SAN FRANCISCO, CA · 5 employees · woman-owned
“Imaging intracerebral and systemic T cell immunity in patients with Alzheimer's disease using 18F-F-AraG”
Department of Health and Human Services · Phase Phase II
Friendi.fi Corporation
Millbrae, CA · 0 employees
“Implementing and Scaling the STEADI Fall Prevention Algorithm Using a Conversational Relational Agent for Community-Dwelling Older Adults wi”
Department of Health and Human Services · Phase Phase II
ACTIVE MOTIF, INC.
CARLSBAD, CA · 62 employees
“A Novel Epigenetic Editing Platform”
Department of Health and Human Services · Phase Phase I
PHOTOZIG INC
CAMPBELL, CA · 8 employees
“CaringGPT: Empowering Dementia Caregivers with Personalized and Accessible Resources to Match Their Needs, Enhance Cope with Caregiving, and”
Department of Health and Human Services · Phase Phase I
S-3 RESEARCH LLC
SAN DIEGO, CA · 8 employees
“Co-designing a mobile tool to improve diversity and inclusivity in AD/ADRD trial participation”
Department of Health and Human Services · Phase Phase I
POSIT SCIENCE CORP
SAN FRANCISCO, CA · 32 employees
“Improving Neurological Health with Acetylcholine via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment (INHANCE-MCI)”
Department of Health and Human Services · Phase Phase II
REELIN THERAPEUTICS, INC.
San Diego, CA · 3 employees
“Identification of next generation gamma-secretase modulators for Alzheimer's disease”
Department of Health and Human Services · Phase Phase I
INTELLIGENT OPTICAL SYSTEMS, INC.
GARDENA, CA · 17 employees
“Laser Ultrasonic Testing for In-Space Welding Environments”
National Aeronautics and Space Administration · Phase Phase I
GLYCYX MOR, INC.
San Francisco, CA · 3 employees
“A Phase 2 Trial of Axelopran Plus Pembrolizumab for the First-Line Treatment of Recurrent/Metastatic HNSCC That Is PD-L1 Positive (PD-L1CPS ”
Department of Health and Human Services · Phase Phase II
MAKEL ENGINEERING, INC.
CHICO, CA · 17 employees
“High Pressure, In-Situ Hydrogen Sensor For Space Based Regenerative Fuel Cell Systems”
National Aeronautics and Space Administration · Phase Phase I
Savage Medical Inc.
Belmont, CA · 4 employees
“Safety and Efficacy Trial of the ColoSeal ICD System for the Treatment of Diverticular Disease Patients”
Department of Health and Human Services · Phase Phase II
EP ANALYTICS, INC..
San Diego, CA · 2 employees · woman-owned
“EP-SOA: A Framework to Enable Transition of High-Fidelity Codes to Heterogeneous Computing Environments”
Department of Defense · Phase Phase I
L'GARDE, INC.
Tustin, CA · 19 employees
“Bolt-On Capture Detumble Deorbit Device”
National Aeronautics and Space Administration · Phase Phase I
FleX Orthopaedics, Inc.
AGOURA HILLS, CA · 5 employees
“A Compliant Intramedullary Stem to Increase Longevity of Revision Total Knee Arthroplasty”
Department of Health and Human Services · Phase Phase I
AeroCytek, Inc
San Diego, CA · 4 employees
“Point-of-care autologous CAR-T cell manufacturing”
Department of Health and Human Services · Phase Phase I
ULTRAMET
PACOIMA, CA · 57 employees
“Thin, Flexible Oxidation-Resistant Coatings for 3D-Woven Carbon Fabric TPS Materials”
Department of Defense · Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II
Torrey Pines Logic, Inc.
San Diego, CA · 24 employees
“Long Range LiDAR (LR-LiDAR)”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
PHASE FOUR, INC.
Hawthorne, CA · 30 employees
“Flight Development of an ASCENT Propellant Decomposition Chamber”
Department of Defense · Phase Phase II
NAVEGA THERAPEUTICS, INC.
SAN DIEGO, CA · 5 employees · woman-owned
“Reformulating NT-Z001 and its delivery route to treat rheumatoid arthritis”
Department of Health and Human Services · Phase Phase I
Astrileux Corporation
Carlsbad, CA · 1 employee · woman-owned
“The Blueprint for Generative AI chips manufactured on the ISS”
National Aeronautics and Space Administration · Phase Phase I
Malama Health, Inc.
STANFORD, CA · 3 employees · woman-owned
“A Specialized Risk-Stratification Platform and Tailored Diabetes Prevention Program for Post-Partum to Reduce Progression to Type 2 Diabetes”
Department of Health and Human Services · Phase Phase I
ORBOTIC SYSTEMS INC
THOUSAND OAKS, CA · 6 employees
“RIDDANCE: Removal of Irregular Debris using Double Assisted Nets with Controlled Enhancement”
National Aeronautics and Space Administration · Phase Phase II
Neuralthread Inc
San Francisco, CA · 6 employees
“TulleKit: Integrated Deep Brain Neural Recording System for Non-Human Primate Models”
Department of Health and Human Services · Phase Phase II
Orbitswarm Inc.
SAN FRANCISCO, CA · 3 employees
“Spatial-Temporal Reservoir Inference with Knowledge-based Enhancements (STRIKE)”
Department of Defense · Phase Phase I
BEHZADI LLC
Stevenson Ranch, CA · 2 employees · woman-owned
“High Dynamic Range Force Torque Sensor”
National Aeronautics and Space Administration · Phase Phase I
ARETE ASSOCIATES
NORTHRIDGE, CA · 464 employees
“Acoustic Training Data”
Department of Defense · Phase Phase I/Phase II
Zero Cognitive Systems, Inc.
Campbell, CA · 27 employees
“HerculesAI: Fast, Reliable, and Secure AI-powered Data Solutions to Automate DoD Workflows”
Department of Defense · Phase Phase I
Integrated Medical Sensors
Irvine, CA · 5 employees
“A Miniaturized and Flexible Continuous Glucose Monitoring Platform”
Department of Health and Human Services · Phase Phase I
HEALTH TEQUITY LLC
OAKLAND, CA · 4 employees · woman-owned
“ACTIVATE: An AI-Enabled Multilingual Platform for Connected and Accessible Care Coordination and Remote Monitoring.”
Department of Health and Human Services · Phase Phase I
ANTA Biotechnologies Corporation
SAN DIEGO, CA · 3 employees · woman-owned
“Automated DNA Extraction in Space”
National Aeronautics and Space Administration · National Science Foundation · Phase Phase I/Phase II
ANGSTROM DESIGNS INC
Santa Barbara, CA · 6 employees
“Photovoltaic Thermal Runaway Test Capability for Advanced Space Solar Cells”
Department of Defense · Phase Phase II
Vaxiion Therapeutics Inc
SAN DIEGO, CA
“Preclinical development of VAX024 - a novel targeted combination STING agonist/oncolytic agent”
Department of Health and Human Services · Phase Phase I
ECLIPSE REGENESIS, INC.
MOUNTAIN VIEW, CA · 3 employees
“Outcomes study for the XL1 distraction enterogenesis device to improve nutrient absorption in short bowel syndrome patients”
Department of Health and Human Services · Phase Phase II
EpiTune
SAN DIEGO, CA · 1 employee
“Novel imaging-based platform for cell quality and identity control”
Department of Health and Human Services · Phase Phase I
MILANOWSKI & ASSOCIATES, INC.
San Diego, CA · 3 employees
“Radiation-Induced Upset Circumvention & Recovery in Modern Electronics Systems”
Department of Defense · Phase Phase II
EIVIE
Watsonville, CA · 9 employees
“The Annular-Wing VTOL Aircraft”
National Aeronautics and Space Administration · Phase Phase I
ADVANCED BRAIN MONITORING, INC.
CARLSBAD, CA · 44 employees
“Characterizing neurocognitive deficits in post-acute sequelae of COVID-19”
Department of Health and Human Services · Phase Phase I
TELEMETRAK INC
OAKLAND, CA · 3 employees
“New Integrated MilSpec ATC Predictive Tool Replacement Toolbox Running Off Central Computer”
Department of Defense · Phase Phase I/Phase II
NOVORON BIOSCIENCE INC
SAN DIEGO, CA · 11 employees
“Human iPSC neural spheroids to screen for compounds that block tau propagation”
Department of Health and Human Services · Phase Phase II
Satlyt
Sunnyvale, CA · 3 employees
“Autonomous QoS Optimization for Delay-Tolerant Mobile Edge Cloud and Content Delivery”
National Aeronautics and Space Administration · Phase Phase I
RYBODYN, INC.
SAN DIEGO, CA · 7 employees
“A novel spatial biology platform for protein profiling which is cost effective and scalable”
Department of Health and Human Services · Phase Phase I
OUTPOST TECHNOLOGIES CORP
Los Angeles, CA · 30 employees
“Autonomous Paragliders for Martian Landings”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
CLARIA MEDICAL, INC
MOUNTAIN VIEW, CA · 7 employees
“A Safe, Fast, and Cost-Effective System for Tissue Removal in Laparoscopic Hysterectomy and Other Minimally Invasive Surgery”
Department of Health and Human Services · Phase Phase II
BLUE MARBLE REHAB INC
ALTADENA, CA · 10 employees · woman-owned
“BREATHE-BRinging Exercise, Asthma Assessments, TeacHing to Everyone”
Department of Health and Human Services · Phase Phase II
ECOTUNE, INC.
IRVINE, CA · 1 employee · woman-owned
“SBIR Phase II: Scalable Development of Fully Bio-Based and High-Performance Bio-Inspired Materials”
National Science Foundation · Phase Phase II
NAVIGATEIO INC.
SANTA ROSA, CA · 5 employees
“Secure Wireless Data Collection for First Responders Using Uncrewed Aircraft Systems”
National Aeronautics and Space Administration · Phase Phase I
PULSE BIOSCIENCES, INC.
HAYWARD, CA · 51 employees
“Minimally invasive pancreatic cancer treatment combining nanosecond electric pulses and immune system stimulants”
Department of Health and Human Services · Phase Phase I
PREDICTIVE SCIENCE INCORPORATED
SAN DIEGO, CA · 16 employees
“Improved Probabilistic Forecasts of Solar Energetic Particles with MagPy”
National Aeronautics and Space Administration · Phase Phase I/Phase II
AMERICAN GNC CORP
SIMI VALLEY, CA · 6 employees · woman-owned
“Robust System Fault Classification & Detection System (RobustDetect)”
National Aeronautics and Space Administration · Phase Phase I
Ceiba Bio Inc.
SAN DIEGO, CA · 2 employees · woman-owned
“Development of Platelet-Derived Exercise Mimetics as a Treatment for Alzheimer's Disease and Alzhimer's Disease Related Dementias”
Department of Health and Human Services · Phase Phase I
IMMUNOWORK LLC
MONROVIA, CA · 2 employees · woman-owned
“Quantifying peripheral blood antigen-specific memory B cells as a new biomarker in patients with PLA2R-associated membranous nephropathy”
Department of Health and Human Services · Phase Phase I
Maguro Surgical Inc
Redwood City, CA · 6 employees · woman-owned
“Developing a magnetic system for endoscopic retrieval of kidney stones”
Department of Health and Human Services · Phase Phase I
TAKEOFF41, INC.
PORTOLA VALLEY, CA · 3 employees
“An AI-driven total parenteral nutrition platform for cost-effective and scientifically personalized nutrition for premature newborns”
Department of Health and Human Services · Phase Phase II
LIVIVOS INC.
SAN DIEGO, CA · 1 employee
“Accurate Point of Care Liver Disease Diagnostics, Phase II”
Department of Health and Human Services · Phase Phase II
PHusis Therapeutics Inc
San Diego, CA · 4 employees · woman-owned
“Clinical evaluation of a novel AKT/PDK1 inhibitor, PHT-427, for the treatment of multi-field actinitc keratoses”
Department of Health and Human Services · Phase Phase II
GIGAMUNE, INC.
SAN FRANCISCO, CA · 3 employees
“A Novel Lentivector for Enhanced In Vivo Delivery of T Cell Receptors for Cell Therapy for Stage IV Melanoma”
Department of Health and Human Services · Phase Phase I
BERENDO SCIENTIFIC LLC
LOS ANGELES, CA · 1 employee
“SleepFlex head and neck exercise program for the treatment of mild to moderate obstructive sleep apnea”
Department of Health and Human Services · Phase Phase I
BIOSETTIA INC
SAN DIEGO, CA · 6 employees
“Targeting endogenous retrovirus Gag genes for biomarker development in type 1 diabetes”
Department of Health and Human Services · Phase Phase I
SNJ PHARMA INC.
TORRANCE, CA · 2 employees · woman-owned
“Novel Plasmin-independent Thrombolytic Agent for Pulmonary Embolism”
Department of Health and Human Services · Phase Phase I
AMPA INC.
SAN DIEGO, CA · 4 employees
“Validation of next-generation TMS system optimizing for widely scalable, personalized treatment of depression”
Department of Health and Human Services · Phase Phase II
AUST DEVELOPMENT, LLC
MOUNTAIN VIEW, CA · 0 employees
“Precision Lead Delivery for Advanced Conduction System Pacing”
Department of Health and Human Services · Phase Phase I
Redwood Neuro Inc
Irvine, CA · 3 employees
“Democratizing Early Detection and Longitudinal Monitoring of Alzheimer's Disease: An Ultra-Sensitive Blood-Based Assay”
Department of Health and Human Services · Phase Phase I
VIS VIVA SPACE LLC
VENTURA, CA · 2 employees
“Campaign Modeling with Data-Oriented Modeling Architectures”
National Aeronautics and Space Administration · Phase Phase I
EVOLOH, INC.
PALO ALTO, CA · 8 employees
“SBIR Phase II: Advanced Anodes for Anion Exchange Membrane Water Electrolyzers”
National Science Foundation · Phase Phase II
UNSTRUCTURED TECHNOLOGIES, INC
LOOMIS, CA · 60 employees
“Unlocking the Power of Unstructured Data: Delivering the RAG-Ready Data Layer for DoD Generative AI Applications”
Department of Defense · Phase Phase I/Phase II
COGNI TRAX
SANTA CLARA, CA · 0 employees
“SBIR Phase II: High Efficiency, Low Cost Catadioptric Waveguide and Display Optical Engine for Augmented Reality Smart Glasses using Spatial”
National Science Foundation · Phase Phase II
Shoonya Digital, Inc
Goleta, CA · 4 employees · woman-owned
“Building Math Literacy Confidence for Early Multilingual Learners: An Inclusive EdTech Solution”
Department of Education · Phase Phase I
ILLUMINANT SURGICAL INC
PALO ALTO, CA · 7 employees
“Scanner Agnostic Image-Guided Biopsy Platform Employing Advanced Computer Vision and Computer Graphics to Enable Non-Invasive Registration a”
Department of Health and Human Services · National Science Foundation · Phase Phase II
Perlara PBC
Alameda, CA · 4 employees
“REMIT (Rescue Mitochondrial Therapeutics): Unlocking Broad-Spectrum Mitochondrial Rescuers”
Department of Health and Human Services · Phase Phase II
Sesh Incorporated
San Diego, CA · 2 employees
“HLA LOH Detection via Liquid Biopsy: A Blood-Based Predictive Biomarker Assay for Precision Immuno-Oncology”
Department of Health and Human Services · Phase Phase I
QUARTUS ENGINEERING INCORPORATED
SAN DIEGO, CA · 165 employees
“Robust LiDAR-Stereo Fusion for Lunar Autonomy”
National Aeronautics and Space Administration · Phase Phase I
THE CALSOYAS GROUP, LLC
OAKLAND, CA · 3 employees
“The Mentor Selection Tool: Empowering Districts to Make Data-Driven Student Teacher Placements”
Department of Education · Phase Phase II
CISLUNE INC
Rosemead, CA · 7 employees
“Terrain Regolith Evaluation And Degradation (TREAD)”
National Aeronautics and Space Administration · Phase Phase I/Phase II
iTherapy, LLC
Vallejo, CA · 4 employees · woman-owned
“Automated Compliance and Communication System for IEP Management Using Blockchain and Conversational AI”
Department of Education · Phase Phase I
Zenobia Therapeutics, Inc.
SAN DIEGO, CA · 3 employees · woman-owned
“Sci-Quest: An Interactive Guided Hero's Journey through the Scientific Method to teach Core Scientific Concepts and Hands-on Skills to Under”
Department of Education · Phase Phase I
EPIGEN BIOSCIENCES INC
SAN DIEGO, CA · 4 employees
“Novel Methods for Nicotinic Receptor Modulation in the Treatment of Post-Operative Pain”
Department of Health and Human Services · Phase Phase I
ALGAE RESEARCH AND SUPPLY, INC
CARLSBAD, CA · 4 employees
“Accessible Microbiology: Algae Bioprospecting as a Gateway to STEM”
Department of Education · Phase Phase I
Project Wayfinder
Berkeley, CA · 64 employees
“Wayfinder IES SBIR Phase 1B 2025”
Department of Education · Phase Phase I
FUTURE ENGINEERS LLC
PASADENA, CA · 9 employees · woman-owned
“SeaQ for STEM Education”
Department of Education · Phase Phase I
Riboscience LLC
Palo Alto, CA · 3 employees
“Inhibitors of ENPP1 for the treatment of hepatocellular carcinoma”
Department of Health and Human Services · Phase Phase I
WECOSO, INC.
HUNTINGTON BEACH, CA · 36 employees
“Miniature 30K Cryocooler”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
MiResource, Inc.
Woodside, CA · 5 employees · woman-owned
“Improving longitudinal mental health monitoring to generate personalized guides and timely referrals”
Department of Health and Human Services · Phase Phase I
Vivid BioInnovations, PBC
SAN FRANCISCO, CA · 10 employees
“FIND-seq: A Novel Cell Sorting Technology to Enable Investigation of Rare Cells in Primary Human Tissues”
Department of Health and Human Services · Phase Phase I
Dropzone Robotics
Santa Clarita, CA · 1 employee
“A Rugged Tactical Perception System for AI-Driven Casualty Registration and Medical Scene Awareness”
Department of Defense · Phase Phase II
EXOANALYTIC SOLUTIONS INC
EL TORO, CA · 133 employees
“FATES Phase II”
Department of Defense · Phase Phase I/Phase II
KEYWISE, INC.
SAN DIEGO, CA · 5 employees
“Passive cognitive assessment across the menopausal transition”
Department of Health and Human Services · Phase Phase I
CORDANCE MEDICAL INC
MOUNTAIN VIEW, CA · 7 employees
“NeuroAccess: a Focused Ultrasound System for SonoBiopsy of the Brain”
Department of Health and Human Services · Phase Phase II
NEURO42 INC
SAN FRANCISCO, CA · 6 employees
“Portable Intraoperative MRI for Neurosurgery”
Department of Health and Human Services · Phase Phase II
NANOS, INC.
LOMA LINDA, CA · 2 employees
“Topical nitrite reverses nitroglycerin tolerance.”
Department of Health and Human Services · Phase Phase I
RERX THERAPEUTICS, INC
BERKELEY, CA · 1 employee
“Evaluation of novel small molecule targeting lipid and energy homeostasis for treating obesity”
Department of Health and Human Services · Phase Phase II
Amydis Diagnostics Inc.
San Diego, CA · 5 employees · woman-owned
“Development of a topical tracer to detect TDP43 in ALS, LATE and FTD retinas for AI-powered disease insights”
Department of Health and Human Services · Phase Phase II
ARTERY THERAPEUTICS INC
SAN RAMON, CA · 3 employees
“Manufacturing of ABCA1 agonist small molecule peptide CS6253 to support chronic toxicology studies in Wistar rats and Cynomolgus monkeys”
Department of Health and Human Services · Phase Phase II
GLYTR THERAPEUTICS, INC.
IRVINE, CA · 1 employee
“Maximizing GlyTR pan-cancer immunotherapy by enhancing target density”
Department of Health and Human Services · Phase Phase I
RADIABEAM TECHNOLOGIES, LLC
SANTA MONICA, CA · 48 employees
“Lightweight High-Energy X-ray Source for In-Space Nondestructive Evaluation”
Department of Defense · Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II
QuSpectra, Inc
San Diego, CA · 2 employees
“High-sensitivity Quantum Spectrometer for Autonomous Biological Analysis”
National Aeronautics and Space Administration · Phase Phase I
ARMIDA LABS, INC.
SAN DIEGO, CA · 2 employees
“Targeting pancreatic cancer metastases with Targefrin”
Department of Health and Human Services · Phase Phase II
ACTIOX LLC
THOUSAND OAKS, CA · 6 employees
“Real-Time Continuous Troponin Monitoring: A Breakthrough in Personalized Cardiovascular Risk Assessment and Management”
Department of Health and Human Services · Phase Phase I
DYNAMOFL, INC.
SAN FRANCISCO, CA · 45 employees
“Comprehensive Controls for Security, Privacy, and Compliance in AI Systems for Army Applications”
Department of Defense · Phase Phase II
Flight Works, Inc.
IRVINE, CA · 43 employees
“Helium Refueling Demonstration for On-Orbit Servicing Applications using Efficient High-Pressure-Ratio Compressor”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
Credo AI
Palo Alto, CA · 55 employees · woman-owned
“AI Governance, Risk Management & Compliance for the AI-Powered Army”
Department of Defense · Phase Phase II
TRETHERA CORPORATION
Sherman Oaks, CA · 1 employee
“Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway through murine studies to enable further clinica”
Department of Health and Human Services · Phase Phase I/Phase II
EXAMINART, LLC
MOUNTAIN VIEW, CA · 3 employees
“Lunar Materials Analyzer (LuMA)”
National Aeronautics and Space Administration · Phase Phase I
CASTELION CORPORATION
Torrance, CA · 90 employees
“Compact Hypersonic Missile/Effector Reactive Material (CHyMERA) Warhead Prototype & Demonstration”
Department of Defense · Phase Phase II
DRIVE MEDICAL, INC
Claremont, CA · 0 employees
“A robotic enteroscope for safe and effective access to the small bowel”
Department of Health and Human Services · Phase Phase I
Aleutian Therapeutics, Inc
LOS ANGELES, CA · 0 employees
“Development of an immune evasive stem cell line for Type 1 diabetes regenerative therapy”
Department of Health and Human Services · Phase Phase I
POLYSENTRY INC
MILL VALLEY, CA · 6 employees
“NeoMode: AI/ML Scaffolding and AI Assurance”
Department of Defense · Phase Phase II
VIVERE ONCOTHERAPIES, INC.
OAKLAND, CA · 8 employees
“Translation of Evolved Oncolytic Virotherapy Product for Colorectal Cancer Treatment”
Department of Health and Human Services · Phase Phase I
SAFETRACES, INC
PLEASANTON, CA · 11 employees
“Rapid Pathogen Intelligence: Field-Deployable, Environmental Biosensing for Military Readiness”
Department of Defense · Phase Phase II
Altamar Technologies Inc
Del Mar, CA · 1 employee
“Maritime Communications transformed through AI”
Department of Defense · Phase Phase II
Holochip Corporation
Torrance, CA · 15 employees
“Prescription Optical Visor for the M50 Air Purifying Respirator”
Department of Defense · Environmental Protection Agency · Phase Phase I/Phase II
MOTIV SPACE SYSTEMS, INC.
PASADENA, CA · 37 employees
“Rad-tolerant Avionics & Mechanisms for the Modern Space Economy- RAMMSE”
National Aeronautics and Space Administration · Phase Phase I/Phase II
INNOTECH SYSTEMS LLC
LA CRESCENTA, CA · 5 employees
“Enhanced Decentralized V2V Communications Leveraging the Potential of Automotive RADAR”
Department of Transportation · Phase Phase II
ADVANCED ROTORCRAFT TECHNOLOGY, INC.
FREMONT, CA · 21 employees
“Automated Airfoil Table Generation for VTOL Aircraft”
National Aeronautics and Space Administration · Phase Phase I
PHNX Materials
San Leandro, CA · 4 employees
“Gallium Acquisition from Landfilled Legacy Ash Novel Technology (GALLANT)”
Department of Defense · Phase Phase I
CTS CEMENT MANUFACTURING CORP
GARDEN GROVE, CA · 250 employees
“An Integral Materials and Logistical Approach to Increasing the Shelf Life of Rapid Setting Cements”
Department of Defense · Phase Phase I/Phase II
QUINSTAR TECHNOLOGY, INCORPORATED
TORRANCE, CA · 130 employees
“Radiation-Hardened Compact W-band Transceiver”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I
AKUA, INC.
WOODSIDE, CA · 6 employees
“Innovative Approach for Conductive Material Seals Tamper Detection Confidence Factor Analytics Utilizing Real World Conductive Seal Test Dat”
Department of Defense · Phase Phase I
VOLCANO PLATFORMS INC
Palo Alto, CA · 5 employees
“Accurate Airframe Noise Predictions Using Large Eddy Simulations”
National Aeronautics and Space Administration · Phase Phase I/Phase II
ADVANCED SCIENTIFIC CONCEPTS, LLC
GOLETA, CA · 33 employees
“On-orbit Reconfigurable LiDAR for Mapping and Hazard Detection”
National Aeronautics and Space Administration · Phase Phase I
AstraQua Inc
Santa Monica, CA · 8 employees
“AstraSense: AI-Driven Health Predictions for Sustainable Aviation”
National Aeronautics and Space Administration · Phase Phase I
AUXILIUM BIOTECHNOLOGIES INC.
SAN DIEGO, CA · 1 employee
“Auxilium Microfabrication Platform Cartridge Modification”
National Aeronautics and Space Administration · Phase Phase I
INTEGRA TECHNOLOGIES, INC.
EL SEGUNDO, CA · 77 employees
“Advanced 150V GaN Solid State Power Amplifier Topologies for High Power Microwave Applications”
Department of Defense · Phase Phase II
SPACE ENVIRONMENT TECHNOLOGIES, LLC
PACIFIC PALISADES, CA · 25 employees
“Producing a Benchmark HASDM Forecast Density Database”
National Aeronautics and Space Administration · Phase Phase I/Phase II
SOFTSONICS LLC
La Jolla, CA · 7 employees
“Wearable cardiac ultrasound imager”
National Aeronautics and Space Administration · Phase Phase I
BAYSPEC, INC.
SAN JOSE, CA · 25 employees
“Miniaturized Ion Trap Mass Spectrometer for In Situ Lunar and Planetary Analysis”
National Aeronautics and Space Administration · Phase Phase I
MYOGENE BIO LLC
SAN DIEGO, CA · 3 employees · woman-owned
“Advancing manufacturing and release testing of a gene editing therapy for Duchenne muscular dystrophy”
Department of Health and Human Services · Phase Phase II
HEALCISIO INC
SAN DIEGO, CA · 5 employees
“Automating Quality to Accelerate Transformational Improvements in Care (AQUATIC)”
Department of Health and Human Services · Phase Phase I
THE AIRD
PLEASANTON, CA · 3 employees · woman-owned
“Commercialization of Optical Coherence Tomography with Advanced Optical Design and Adaptive Optics for Rodent Eye”
Department of Health and Human Services · Phase Phase I
NEWOMICS INC.
Berkeley, CA · 6 employees
“Multispray Technology for Studying Biomolecular Interactions”
Department of Health and Human Services · Phase Phase II
CELLFE, INC
ALAMEDA, CA · 14 employees
“Accelerated, scalable same-day microfluidic sequential gene editing for allogeneic cell therapy”
Department of Health and Human Services · Phase Phase I
Rebound Health Inc
San Francisco, CA · 4 employees · woman-owned
“Development and Validation of a Scalable, Self-Guided Trauma Wellness App to Expand Access to Trauma-Focused Mental Health Care”
Department of Health and Human Services · Phase Phase I
KHEMIA METALS INC
SAN CARLOS, CA · 0 employees
“SBIR Phase II: Metal Foils for High Energy Density, Low-cost, Lithium-ion Batteries”
National Science Foundation · Phase Phase II
Evanesc Therapeutics, Inc.
ENCINO, CA · 3 employees
“Non-invasive Medical Device to Permeabilize the Blood-Brain Barrier Using Low Power Radio Frequency Evanescent Waves”
Department of Health and Human Services · Phase Phase I
MAGNETIC TIDES INC
EL CERRITO, CA · 4 employees
“A novel method of non-invasive brain stimulation to enhance motor function in chronic stroke patients”
Department of Health and Human Services · Phase Phase I/Phase II
EYE-PREDICT LLC
Los Angeles, CA · 5 employees
“Complete Mental Counts for Patients Recovering from Brain Injury”
Department of Health and Human Services · Phase Phase I
MILLION MARKER WELLNESS INC
EL CERRITO, CA · 10 employees · woman-owned
“Reducing rural health disparities by empowering people to minimize PFAS exposure and improve cardiovascular health”
Department of Health and Human Services · Phase Phase I
LUTRIS, INC.
BERKELEY, CA · 3 employees
“SBIR Phase II: Massively Parallel Protocols for Software-based Wireless Instrumentation”
National Science Foundation · Phase Phase II
NUCB1 Holdings LLC
San Francisco, CA · 1 employee
“Development of amyloid conformer-targeting technologies in type 2 diabetes mellitus”
Department of Health and Human Services · Phase Phase I
AVERY DIGITAL DATA, INC.
LA JOLLA, CA · 3 employees
“Integrated Circuit Electrical DNA Assembly”
Department of Health and Human Services · Phase Phase II
Synvect, Inc
San Diego, CA · 6 employees
“NextGenSIT: An Off-the-Shelf and On-Demand Product for Biological Control of Aedes aegypti Mosquitoes”
Department of Health and Human Services · Phase Phase I
Dogpatch Medical LLC
San Francisco, CA · 2 employees · woman-owned
“MAGNETIC (MRI-Assisted Guidance via NeuroInterventional Targeted Imaging Catheters)”
Department of Health and Human Services · Phase Phase I
Aveera Medical Inc.
San Clemente, CA · 10 employees
“Preventing major amputations and preserving functional limbs in no option critical limb-threating ischemia patients”
Department of Health and Human Services · Phase Phase II
Auricle Inc
San Francisco, CA · 2 employees
“A Novel Technology to Treat the Underlying Cause of Tinnitus”
Department of Health and Human Services · Phase Phase I
Eye C Better
La Quinta, CA · 1 employee
“New, Non-Invasive (No-Puff, No-Touch), Tonometry Method: Remote photonic IOP biomonitoring using the damping factor of transitional oscilla”
Department of Health and Human Services · Phase Phase I
PICOGRID, INC.
EL SEGUNDO, CA · 55 employees
“Low-Altitude Passive Integrated Sensors (LAPIS)”
Department of Defense · Phase Phase II
SKYFRONT CORP
REDWOOD CITY, CA · 9 employees
“UAV Hybrid Power System for Frontline Resupply and Loitering Munition Delivery”
Department of Defense · Phase Phase II
GRAYMATTER ROBOTICS INC.
Carson, CA · 78 employees
“Smart Robotic Canopy Sanding”
Department of Defense · Phase Phase I/Phase II
SAMARA AEROSPACE, INC.
San Francisco, CA · 9 employees
“Active Spacecraft Jitter Cancellation Using Deployable Panels”
National Aeronautics and Space Administration · Phase Phase I
YURTS TECHNOLOGIES, INC.
SAN RAFAEL, CA · 6 employees
“Yurts Platform for Intelligence Analysis and COAs”
Department of Defense · Phase Phase II
INHANCE DIGITAL CORPORATION
LOS ANGELES, CA · 15 employees
“Mixed Reality Platform for Aircraft Maintenance (MRMX)”
Department of Commerce · Department of Defense · Phase Phase I/Phase II
WORKERA CORP.
PALO ALTO, CA · 55 employees
“Benchmarking Data Analytics, AI and Operations Research Skills to World-Class Standards and Customizing Source-Agnostic Learning Paths”
Department of Defense · Phase Phase II
AELUMA, INC.
GOLETA, CA · 18 employees
“SHIPS: Scalable Heterogeneous Integration for Photon-entanglement Sources”
Department of Defense · Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II
Navi AI, Inc.
San Franicsco, CA · 4 employees
“Project WingMan”
Department of Defense · Phase Phase I/Phase II
SWIFT ENGINEERING INC.
SAN CLEMENTE, CA · 56 employees
“Swift Ultra Long Endurance (SULE) High-Altitude Platform Systems (HAPS) Capability Demonstration”
National Aeronautics and Space Administration · Phase Phase II
GRID RASTER INC
MOUNTAIN VIEW, CA · 17 employees
“Multimodal Dynamic Spatial Tracking for Enhanced Automatic Manufacturing – Extended Reality (STEAM-XR)”
Department of Defense · Phase Phase I/Phase II
Paratus AI, Inc
San Francisco, CA · 5 employees
“Generative AI Platform for Automating Personnel Readiness”
Department of Defense · Phase Phase I
SARANIASAT INC.
TUJUNGA, CA · 3 employees
“Generative AI for Automatic Target Recognition via Sparse, Multimodal Sensing”
Department of Defense · Phase Phase I
MICROSURGEONBOT INC
SYLMAR, CA · 5 employees
“OrbitGuard: From Data Deluge to Decision Dominance”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II
Pytho AI
San Bruno, CA · 2 employees
“Autonomous COA Engine for Multi-Domain Operations”
Department of Defense · Phase Phase I
PREWITT RIDGE INC
LOS ANGELES, CA · 11 employees
“State Machine to SysML v2 State Machine via Graph Recognition”
Department of Defense · Phase Phase I
FIREFLOWER AI INC
CARDIFF, CA · 3 employees
“Fireflower Ignite Secure GenAI Platform for Federal”
Department of Defense · Phase Phase I
SPECTRUM SCIENTIFIC INCORPORATED
IRVINE, CA · 20 employees · woman-owned
“Creating Blazed Gratings for Freeform Mirror Surfaces”
National Aeronautics and Space Administration · Phase Phase II
RED RIVER RESOURCES LLC (dba Navaide)
SAN DIEGO, CA · 94 employees · woman-owned
“Navaideĺs AI-Driven Decision Support Framework”
Department of Defense · Phase Phase I
ADVANCED ONION INC
MONTEREY, CA · 74 employees
“Enhancing Supply Chain Management with LLMs: A Next Generation Chat Assistant Framework for Natural Language Queries”
Department of Defense · Phase Phase I
Flosonics Medical LLC
Mountain View, CA · 52 employees
“FloPredict - DOPPLER INTELLIGENCE: ADVANCING AI-POWERED HEMODYNAMIC MONITORING FOR EARLY DETECTION OF CLINICAL DETERIORATION”
Department of Defense · Phase Phase II
HELIOSPACE CORPORATION
BERKELEY, CA · 44 employees
“Deployable Baffle by SABER System (DeBSS)”
National Aeronautics and Space Administration · Phase Phase I/Phase II
AOSENSE, INC.
FREMONT, CA · 36 employees
“Advanced Narrow-linewidth Tunable Laser for Rydberg Sensors (ANTLRS)”
National Aeronautics and Space Administration · Phase Phase I
ODYS AVIATION, INC.
LONG BEACH, CA · 47 employees
“High Efficiency Turbogenerator for Group III UAV”
Department of Defense · Phase Phase I/Phase II
MATREGENIX INC
Mission Viejo, CA · 6 employees
“Streamlined Synthetic Amniotic Membrane for Ocular Penetrating Injuries and Burns: Simplified Logistics, No Special Storage, Extended Shelf ”
Department of Defense · Department of Health and Human Services · Phase Phase I/Phase II
Faraday Labs Inc
Santa Monica, CA · 5 employees
“T B D”
Department of Defense · Phase Phase I/Phase II
TG SKY
SAN DIEGO, CA · 12 employees
“Next-Gen Wireless Asset Tracking: A Permanent Solution for Department of the Air Force IT Logistics”
Department of Defense · Phase Phase I/Phase II
Intelligenic, Inc
San Jose, CA · 6 employees
“Intelligenic Proposal for OSD254-P001”
Department of Defense · Phase Phase I
ARITH INC
PALO ALTO, CA · 1 employee
“MIGHTYFP™ - A SWAPC2-OPTIMIZED AI ACCELERATOR FOR DEFENSE AND AEROSPACE APPLICATIONS”
Department of Defense · Phase Phase I/Phase II
DeepNight Inc.
San Francisco, CA · 10 employees
“Night Vision Reconnaissance Augmentation System (NRAS)”
Department of Defense · Phase Phase I/Phase II
Gambit Defense, Inc.
VALLEY VILLAGE, CA · 8 employees
“Spectrum Supremacy Utilizing a Mesh Network: NEURON”
Department of Defense · Phase Phase I/Phase II
Cicero Technologies INC
Pacifica, CA · 50 employees
“ACR: Augmented Contract Review Application”
Department of Defense · Phase Phase II
ImmPORT Therapeutics Inc dba Antigen Discovery Inc
Irvine, CA · 15 employees
“A sensitive and specific serology test for evaluating potency of whole cell Pertussis vaccines”
Department of Health and Human Services · Phase Phase I
Alare Technologies, LLC
Moorpark, CA · 19 employees
“Mobile Target Tracking”
Department of Defense · Phase Phase II
MONDE WIRELESS INC
GOLETA, CA · 9 employees
“Removing Heat from Next Generation Wireless Systems”
Department of Defense · Phase Phase II
RIX INDUSTRIES
BENICIA, CA · 178 employees
“Autonomous Dynamic Load Adjusted Central Tire Inflation System (ADLACTIS)”
Department of Transportation · Phase Phase I
Ethos Space Corp.
Los Angeles, CA · 9 employees
“Lunar In-Situ Thermal Wadis”
National Aeronautics and Space Administration · Phase Phase I
PLANETTE ANALYTICS INC
FREMONT, CA · 4 employees · woman-owned
“QubitCast: A Quantum-Inspired Environmental Forecasting System”
National Aeronautics and Space Administration · National Science Foundation · Phase Phase I
PACIFIC MICROCHIP CORP.
CULVER CITY, CA · 7 employees
“A Low-Power 14GHz Spectrometer ASIC”
National Aeronautics and Space Administration · Phase Phase I/Phase II
GENERAL LASERTRONICS CORPORATION
FREMONT, CA · 5 employees
“Portable Laser Removal Tool, Phase II”
Department of Defense · Phase Phase II
PARABILIS SPACE TECHNOLOGIES, INC.
SAN MARCOS, CA · 16 employees
“Green Propellant Rapid Orbital Mobility Bus”
National Aeronautics and Space Administration · Phase Phase I/Phase II
Programs Management Analytics & Technologies, Inc.
San Diego, CA · 37 employees
“Dynamic Rerouting Optimization for Platforms and Sensors (DROPS)”
Department of Defense · Phase Phase II
Peregrine Falcon Corporation
PLEASANTON, CA · 8 employees
“OSD233-003 Specialized Crystal Growth and Material Characterization”
Department of Defense · Phase Phase II
EarthTraq Corporation
San Carlos, CA · 3 employees
“Multi-Spacecraft On-orbit Space Computing Testbed”
National Aeronautics and Space Administration · Phase Phase I
BRIGHT APPS LLC
WALNUT CREEK, CA · 30 employees
“BrightArc: A Generative AI Framework for Automating Video Analysis and Enhancing Efficiency in Government Operations”
Department of Defense · Phase Phase I
STELL ENGINEERING, INC.
MARINA DEL REY, CA · 12 employees · woman-owned
“Requirements Operating System for Integrated Engineering (ROSIE) AI”
Department of Defense · Phase Phase II
REBEL SPACE TECHNOLOGIES INC
LONG BEACH, CA · 10 employees
“Muse: Accelerating Test & Evaluation with Generative AI for Next-Generation Defense Systems”
Department of Defense · Phase Phase II
OBSIDIAN SENSORS INC
SAN DIEGO, CA · 16 employees
“Highly Scalable Readout Integrated Circuit (ROIC) with Thermal Image Processor Chip to Support the 12um SXGA Microbolometer on Glass Develop”
Department of Defense · Phase Phase I/Phase II
Fitoto Technologies Inc.
Oakland, CA · 2 employees
“SBIR Fast-Track: Providing Timely, Inexpensive, and Comfortable Earmolds (EMs) for Hearing Loss (HL) Patients using Computed Axial Lithograp”
National Science Foundation · Phase Phase I/Phase II
Rubato, Inc.
Pacific Palisades, CA · 5 employees
“Novel AI-driven music-based intervention to reduce behavioral and psychological symptoms for people living with dementia”
Department of Health and Human Services · Phase Phase I
Organos, Inc.
Berkeley, CA
“Microheart muscle based discovery and development of inotropic compounds”
Department of Health and Human Services · Phase Phase II
Toi Labs, Inc.
San Francisco, CA · 5 employees
“Use of a Novel Toilet Seat to Passively Collect Digital Biomarkers in Assisted Living Settings”
Department of Health and Human Services · Phase Phase II
IMMUNOMATICS, INC.
SAN MARCOS, CA · 1 employee
“Eliminating Donor Availability Disparities in Hematopoietic Stem Cell Transplantation with AI-based Prediction of Permissive HLA Mismatches ”
Department of Health and Human Services · Phase Phase I
Modalai Inc
San Diego, CA · 45 employees
“VOXL 3 - Maximizing Image Processing per Gram”
Department of Defense · Phase Phase I/Phase II
REALSEQ BIOSCIENCES, INC.
Santa Cruz, CA · 4 employees
“Preparation of sequencing libraries for multi-analyte analysis of RNAs”
Department of Health and Human Services · Phase Phase II
REVEL PHARMACEUTICALS INC.
SAN FRANCISCO, CA · 8 employees
“Development of enzymatic tools for rapid measurement of Advanced Glycation and Lipoxidation End Product-protein adducts”
Department of Health and Human Services · Phase Phase I/Phase II
ALIDA BIOSCIENCES INC.
SAN DIEGO, CA · 15 employees
“Pseudouridine detection with single-base resolution in a multiplexed epitranscriptomics assay”
Department of Health and Human Services · Phase Phase II
VISIONARY TECH & EVENT SOLUTIONS LLC
Santa Clara, CA · 1 employee
“VOCAL: Voice Originality Cloning Across Languages”
Department of Defense · Phase Phase I
OAK THERAPEUTICS INC
WESTLAKE VILLAGE, CA · 4 employees
“Oral Dissolvable Strips (ODS) as new pediatric and adult delivery mode of therapy for latent tuberculosis”
Department of Health and Human Services · Phase Phase II
SENSEEKER CORP
SANTA BARBARA, CA · 39 employees
“Optimized Multi-Spectral Digital Pixel Readout IC”
Department of Defense · Phase Phase I/Phase II
ORIGAMI THERAPEUTICS, INC.
SAN DIEGO, CA · 2 employees · woman-owned
“Uncovering the molecular target(s) of ORI-113, a potential brain-penetrant small molecule therapeutic for Huntington's disease.”
Department of Health and Human Services · Phase Phase I
Flexlynqs LLC
Fremont, CA · 7 employees
“FleetLynq: AI-driven Decision Support Solution for Transit Fleet”
Department of Transportation · Phase Phase I
TENDEL THERAPIES INC
KENSINGTON, CA · 5 employees
“Optimizing SIV reservoir depletion by Tendel bsAb-98”
Department of Health and Human Services · Phase Phase II
ADVANCED SYSTEMS & TECHNOLOGIES INC
IRVINE, CA · 5 employees
“Sensor-Array Broadband Express-Rate Wavefront Sensor (SABER_WFS)”
Department of Defense · Phase Phase II
TIAMI NETWORKS
ELK GROVE, CA · 12 employees
“Diffusion-based spectrum monitoring and awareness in real time”
Department of Defense · Phase Phase I/Phase II
NABLA ZERO LABS
SOUTH PASADENA, CA · 3 employees
“Missfit: Statistical Multi-Event Missed-Thrust Optimization for Low-Thrust Trajectories”
National Aeronautics and Space Administration · Phase Phase II
ZabBio, Inc.
San Diego, CA · 2 employees
“Development of a monoclonal therapy for neonatal herpes”
Department of Health and Human Services · Phase Phase I
PROTABIT, LLC
PASADENA, CA · 5 employees
“High-Throughput Engineering of Bispecific Antibodies”
Department of Health and Human Services · Phase Phase I
PARALLEL FLIGHT TECHNOLOGIES, INC.
WATSONVILLE, CA · 8 employees
“Modifications to Firefly to make maritime compatible”
Department of Defense · Phase Phase II
TYFAST ENERGY CORP
SAN DIEGO, CA · 10 employees
“Domestically Sourced and Globally Superior LVO Battery Technology for Directed Energy Weapons”
Department of Defense · Phase Phase I
LEIDEN MEASUREMENT TECHNOLOGY LLC
SUNNYVALE, CA · 4 employees
“CHESS: Compact High-Entendue Spectrometer for Space”
National Aeronautics and Space Administration · Phase Phase II
BIOSPHERICAL INSTRUMENTS, INC.
SAN DIEGO, CA · 41 employees
“Hyperspectral Optical Profiling System with Advanced Dynamic Vertical Sampling Resolution (Hy-OPS ADVSR)”
National Aeronautics and Space Administration · Phase Phase II
Siolta Therapeutics, Inc.
San Carlos, CA · 9 employees
“Development of a multispecies live biotherapeutic product for the prevention of recurrent bacterial vaginosis”
Department of Health and Human Services · Phase Phase II
Endure Biotherapeutics, Inc.
CARLSBAD, CA · 3 employees
“Development of Novel Engineered Native Bacteria (ENB) for the Treatment of Familial Adenomatous Polyposis”
Department of Health and Human Services · Phase Phase I
Onc.AI, Inc.
San Carlos, CA · 17 employees
“Deep Learning Serial Radiomics for Improved Cancer Therapy Response Assessment.”
Department of Health and Human Services · Phase Phase II
TEGA THERAPEUTICS INC
SAN DIEGO, CA · 7 employees
“Title: New Clinical Biomarkers for GM1 Gamgliosidosis”
Department of Health and Human Services · Phase Phase I
ZEPHYR COMPUTING SYSTEMS, INC.
OAKLAND, CA · 8 employees
“Peregrine Falcon - Modular Multi-Mission Processing for Spacecraft”
Department of Defense · Phase Phase II
Spectral Therapeutics, INC.
SAN MARCOS, CA · 4 employees
“Production of Stimulated Emission-Encoded Beads for Large Molecular Library Generation”
Department of Health and Human Services · Phase Phase I
NANOELECTRONIC IMAGING, INC.
RIVERSIDE, CA · 4 employees
“Thermal NanoImaging of Semiconductor Devices”
Department of Commerce · Phase Phase I
Space Information Laboratories, LLC
Santa Maria, CA · 23 employees · woman-owned
“VBIRS Space Based Range”
Department of Defense · Phase Phase II
TOPAZ BIOSCIENCES, INC.
EMERYVILLE, CA · 7 employees · woman-owned
“Development of novel endolysins targeting Cutibacterium acnes to treat acne vulgaris”
Department of Health and Human Services · Phase Phase II
Ometa Labs LLC
Oceanside, CA · 6 employees
“Bioinformatics platform for large scale untargeted metabolomics analysis”
Department of Health and Human Services · Phase Phase II
AUTONOMOUS HEALTHCARE INC.
SANTA CLARA, CA · 8 employees
“Noncontact Monitoring for the Detection of Opioid-Induced Respiratory Depression”
Department of Health and Human Services · Phase Phase II
SmartAirway LLC
VENICE, CA · 2 employees
“A Novel Articulating Stylet for Improving First-Pass Intubation Success”
Department of Health and Human Services · Phase Phase I
CISTERNA BIOLOGICS, INC.
OCEANSIDE, CA · 1 employee
“A Novel Approach to Eliminate Length Impurities for High-Quality mRNA Production”
Department of Health and Human Services · Phase Phase I
SPIKEGADGETS, INC.
SAN FRANCISCO, CA · 10 employees
“A Commercial Platform for High-Volume Behavior and Electrophysiology Research”
Department of Health and Human Services · Phase Phase II
IMVARIA INC
BERKELEY, CA · 3 employees
“A fully automated tool for more accurate malignancy assessment in pulmonary nodules from chest CT”
Department of Health and Human Services · Phase Phase I
CAPIENDA BIOTECH, LLC
San Diego, CA · 3 employees
“High-throughput kinetic system for small-molecule drug discovery”
Department of Health and Human Services · Phase Phase I
Engage Biologics Inc
San Carlos, CA · 5 employees
“Tethosomes: a non-viral DNA platform for durable expression of therapeutic transgenes in specific target cells”
Department of Health and Human Services · Phase Phase II
OXYLO, INC.
SAN DIEGO, CA · 3 employees
“Oxygen reducing microcapsules for in vitro control of hypoxia”
Department of Health and Human Services · Phase Phase I
VIBO HEALTH INC
LOS ANGELES, CA · 2 employees
“Phantoms for Mobile MRS Calibration and Testing”
Department of Commerce · Phase Phase I
CALIS BOOKS INC
LOS ANGELES, CA · 10 employees · woman-owned
“Introducing Young Children to Biomedical Science with a Screenless Interactive Device (infinibook)”
Department of Health and Human Services · National Science Foundation · Phase Phase I/Phase II
SILICON KIDNEY LLC
San Francisco, CA · 5 employees
“An intravascular Bioartificial Pancreas (iBAP)”
Department of Health and Human Services · Phase Phase II
CELESTIAL THERAPEUTICS INC
IRVINE, CA · 2 employees
“Development of a dry powder inhalation product against Respiratory Syncytial Virus based on an endogenous anionic pulmonary surfactant lipid”
Department of Health and Human Services · Phase Phase II
PROTERIS BIOTECH, INC.
GLENDALE, CA · 3 employees
“Clusterin Targeting Epitheliopathy for Dry Eye”
Department of Health and Human Services · Phase Phase I
VERISIM LIFE, INC
SAN FRANCISCO, CA · 9 employees · woman-owned
“Development of therapeutic candidates for stimulant use disorder using AI-driven platform for focused drug discovery and accelerated develop”
Department of Health and Human Services · Phase Phase II
Novoglia, Inc.
Irvine, CA · 4 employees
“Engineered microglia for the treatment of Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)”
Department of Health and Human Services · Phase Phase II
CYTORUM, INC.
SANTA CLARA, CA · 2 employees
“Xbeads: A Platform for Flow Cytometry Sample QC and Harmonization”
Department of Health and Human Services · Phase Phase II
ViVita Technologies, Inc.
Woodland, CA · 1 employee
“Unfixed, xenogeneic extracellular matrix for crimp damage-resistant and regenerative transcatheter heart valve prostheses”
Department of Health and Human Services · Phase Phase I
PUMPKINSEED TECHNOLOGIES INC
PALO ALTO, CA · 3 employees
“SBIR Phase II: High-throughput De-novo Peptide Sequencing with Metasurface Optics”
Department of Health and Human Services · National Science Foundation · Phase Phase I/Phase II
TANGRAM ROBOTICS, INC.
BURLINGAME, CA · 6 employees
“A low-power, high-dynamic range sensor system for long-term autonomy, navigation, and mapping on the lunar surface”
National Aeronautics and Space Administration · Phase Phase II
AUTONOMOUS DEFENSE TECHNOLOGIES CORP.
OXNARD, CA · 10 employees
“Autonomous Collaborative Platform (ACP) Low-Cost, High-Volume Manufacturing”
Department of Defense · Phase Phase I/Phase II
COBRA SCIENTIFIC, LLC
ANAHEIM, CA · 5 employees
“Cobra AF251-D003”
Department of Defense · Phase Phase II
PROTONEX LLC
Windsor, CA · 20 employees
“PNI Sensor Enhanced Pilot Locator Beacon for GPS Denied Environments”
Department of Defense · Phase Phase I/Phase II
SQUID3 SPACE, INC.
Irvine, CA · 5 employees
“Operationally Responsive Textile Manufacturing using Collaborative Robots”
Department of Defense · Phase Phase I
UNITED SEMICONDUCTORS, LLC
LOS ALAMITOS, CA · 5 employees · woman-owned
“Physical vapor deposition reactor design and validation for in-space manufacturing of aluminum nitride single crystals”
National Aeronautics and Space Administration · Phase Phase II
ONENAV, INC
SUNNYVALE, CA · 33 employees
“TBD”
Department of Defense · Phase Phase II
AVATAR PARTNERS INC
IRVINE, CA · 25 employees · woman-owned
“EOD_XR Dual Mode Immersive Training”
Department of Defense · Phase Phase I
Northstar Photonics, Inc.
SAN JOSE, CA · 19 employees
“Reduced Half-Wave Voltage in Integrated Optical Circuits for Interferometric Fiber Optic Gyroscopes”
Department of Defense · Phase Phase II
REAL-TIME INNOVATIONS, INC.
SUNNYVALE, CA · 267 employees
“APIARY: Aegis Platform Integration of Aerial Robotic sYstems”
Department of Defense · Phase Phase I
SPARK THERMIONICS, INC.
BERKELEY, CA · 4 employees
“Affordable Integrated Surface Modification of Ceramic and Refractory Substructures with UHTCs for High Temperature Resilient Thermal Protect”
Department of Defense · Phase Phase I
CHAOS 1, INC.
Hawthorne, CA · 230 employees
“GRIFFIN - Passive, Expeditionary Air Defense Radar”
Department of Defense · Phase Phase II
ATMO, INC.
San Francisco, CA · 10 employees
“Classified AI Weather Forecasting for USAF Operations”
Department of Defense · Phase Phase II
EXERGY SYSTEMS, INC.
Irvine, CA · 8 employees · woman-owned
“Lightweight Portable Water Purification Systems for Military Field Operations”
Department of Defense · Phase Phase I
FARAD POWER INC
HILLSBOROUGH, CA · 2 employees
“Synthetic Graphite from Biomass as Anode Material for 6T Batteries”
Department of Defense · Phase Phase I/Phase II
SCHEMATA INC.
SAN FRANCISCO, CA · 12 employees
“Traverse3D Unlocking Scalable Immersive Training for Enhanced Readiness”
Department of Defense · Phase Phase I/Phase II
QUANTUM VENTURA INC
SAN JOSE, CA · 10 employees
“Advanced Mechanical Metamaterials & High-Entropy Alloys for hypersonics”
Department of Defense · Department of Energy · Phase Phase I
RIMARK TECHNOLOGY INC
SEBASTOPOL, CA · 1 employee
“Solstice Smart Contract Supply Chain Platform”
Department of Defense · Phase Phase I
Arize AI, Inc
Mill Valley, CA · 90 employees
“Advanced LLM Evaluation and Development Tooling for Strategic USAF AI Integration - AFRL NIPRGPT”
Department of Defense · Phase Phase II
PACIFIC SCIENCE & ENGINEERING GROUP, INC.
SAN DIEGO, CA · 60 employees
“FormAID: A general purpose, receiver-centric, Artificial Intelligence (AI)-assisted system for effective naval reporting”
Department of Defense · Phase Phase II
INNSIGHTFUL INC
SUNNYVALE, CA · 7 employees
“An AI-Powered Co-Pilot for Suicide Detection and Inclusive Mental Health Support”
Department of Defense · Phase Phase I/Phase II
PERCEPTRA TECHNOLOGIES, INC.
OAKLAND, CA · 3 employees
“High-throughput micro-Raman Aerosol Analyzer”
Department of Defense · Department of Homeland Security · Phase Phase I
BluumBio
ALBANY, CA · 7 employees · woman-owned
“Reducing PFAS Exposure Through In-situ Microbial Remediation of PFAS Impacted Matrixes”
Department of Health and Human Services · Phase Phase I
ANELLO PHOTONICS INC
SANTA CLARA, CA · 23 employees
“NAVAIR Open Topic for Logistics in a Contested Environment”
Department of Defense · Phase Phase II
D&G ANALYTICS INC.
SUNNYVALE, CA · 16 employees
“Expanding Software Integrity Platform (SIP) Coverage Beyond Basic Windows Software Applications”
Department of Defense · Phase Phase II
Kapha Bio
Benicia, CA · 2 employees · woman-owned
“STTR Phase I: A Platform of Biomimetic Mucins for Addressing Recurrent Infections”
National Science Foundation · Phase Phase I
Arkham Technology Limited
Irvine, CA · 15 employees · woman-owned
“Efficient Automated Key Management for pLEO Operations”
Department of Defense · Phase Phase II
KNOUBIS BIO INC
LA JOLLA, CA · 1 employee
“Bispecific biologic for rheumatoid arthritis therapy”
Department of Health and Human Services · Phase Phase I
Ali Far
SARATOGA, CA
“SBIR Phase II: Preventative Maintenance AI Chip: Software-Configurable, Tiny, Low-Latency, Always-On, Ultra-Low-Power, Near-Sensor-AI, No C”
National Science Foundation · Phase Phase II
HYPERCOMP INC
THOUSAND OAKS, CA · 15 employees · woman-owned
“Modeling the Performance of VLF Antennas designed to interact with the Magnetized Plasma in Earth’s Magnetosphere”
Department of Defense · Phase Phase I
NovaTech Innovations LLC
San Diego, CA · 3 employees · woman-owned
“STTR Phase I: Cutting-Edge Nitride Based Distributed Bragg IR-Reflectors”
National Science Foundation · Phase Phase I
KINETIC RIVER CORP.
MOUNTAIN VIEW, CA · 5 employees
“Compensation-Free Flow Cytometer with Expanded Reagent Choices and Reduced Manufacturing Costs”
Department of Health and Human Services · Phase Phase II
COGNICOM INC
SAN DIEGO, CA · 11 employees
“Neptune Radio Improvement for Logistics in a Contested Environment”
Department of Defense · Phase Phase I/Phase II
MUON SPACE INC
MOUNTAIN VIEW, CA · 240 employees
“Adapting Existing Multispectral Scanning Payload for Missile Warning / Missile Track”
Department of Defense · Phase Phase I/Phase II
DittoLive Incorporated
BERKELEY, CA · 60 employees
“DITTO STRATEGIC FUNDING INCREASE: UNIFIED EDGE SYNC PLATFORM”
Department of Defense · Phase Phase II
SimInsights, Inc.
Irvine,, CA · 6 employees
“FIATSim: Flexible Immersive Adaptive Training Simulations”
Department of Defense · Phase Phase I
IPERFORMX LLC
NEWPORT BEACH, CA · 40 employees
“Multi-Disciplinary Enhancement of Adaptive Naval Aviation Training”
Department of Defense · Phase Phase I
AO TECHNOLOGIES, LLC
Glendale, CA · 2 employees
“Development of a high performance reduced cost OCT Otoscope”
Department of Health and Human Services · Phase Phase I
CALNETIX TECHNOLOGIES LLC
Cypress, CA · 171 employees
“Bi-directional Export Power Inverter for Ground Vehicles”
Department of Defense · Phase Phase II
IMAGIZE, LLC
BERKELEY, CA · 8 employees
“Digital Multisensory Augmented Reality for Special Warfare (DMARS)”
Department of Defense · Phase Phase II
LAIRSON BRUCE
VENTURA, CA · 1 employee
“Large Silicon Carbide Grids for X-Ray Microcalorimeter Blocking Filters”
National Aeronautics and Space Administration · Phase Phase II
Hedral Inc.
San Francisco, CA · 18 employees
“AI for Adaptive 3D Infrastructure Design in Navy Engineering”
Department of Defense · Phase Phase I/Phase II
HJ SCIENCE & TECHNOLOGY INC
SAN LEANDRO, CA · 5 employees
“Rapid portable detection technology for wastewater and solidwaste”
Department of Defense · Phase Phase II
SCIENTIFIC APPLICATIONS & RESEARCH ASSOCIATES, INC.
CYPRESS, CA · 295 employees
“Persistent Airbrn CUAS Surveil (PANCAS)”
Department of Defense · Phase Phase I/Phase II
STRATIN LLC
Hawthorne, CA · 21 employees
“Coordinated High-efficiency Autonomous Recharge and Generation of Energy for Drones (CHARGED)”
Department of Defense · Phase Phase I/Phase II
SOLID STATE BATTERY INCORPORATED
FULLERTON, CA · 5 employees
“Composite Solid Polymer Electrolyte (CPSE) Solid State Battery for UAS”
Department of Defense · Phase Phase I
ENGINEERING AND SOFTWARE SYSTEM SOLUTIONS, INC.
SAN DIEGO, CA · 205 employees · woman-owned
“Removable Smart Tooling for High Temperature Composite Fabrication”
Department of Defense · Phase Phase I/Phase II
Tanner Research, Inc.
Duarte, CA · 15 employees · woman-owned
“Retrofittable Probe Latching Detection Concepts for Unmanned Aerial Refueling”
Department of Defense · Phase Phase I/Phase II
ODMR Technologies, Inc
El Cerrito, CA · 3 employees
“Diamond NMR spectrometer for microfluidic metabolite profiling”
Department of Health and Human Services · Phase Phase II
ADTECH PHOTONICS, INC.
CITY OF INDUSTRY, CA · 25 employees · woman-owned
“Single-Mode Continuous-Wave InP-Based Photonic Crystal Surface Emitting Lasers at 2 µm”
Department of Defense · Phase Phase II
CMSOFT, INC.
PALO ALTO, CA · 4 employees
“High-Performance Partitioned Analysis Procedures for Fluid-Thermal-Structural Interactions in Hypersonic Air-Breathing Systems”
Department of Defense · Phase Phase I
MENTIA DTX ,INC.
NOVATO, CA · 2 employees
“An AI-based empathic virtual companion to track changing health states in persons living with dementia”
Department of Health and Human Services · Phase Phase I
INVVAX INC
CYPRESS, CA · 3 employees
“SBIR Phase II: Stable Prophylactic Antibodies”
National Science Foundation · Phase Phase II
CARI HEALTH INC
SAN DIEGO, CA · 6 employees
“Methadone Dosing System (MDS)”
Department of Health and Human Services · Phase Phase II
VIVREON BIOSCIENCES LLC
San Diego, CA · 4 employees
“Preclinical Characterization of CRAC Channel Inhibitors for the Treatment of Alzheimer's Disease”
Department of Health and Human Services · Phase Phase II
VORTEX MEDICAL INC.
WOODSIDE, CA · 4 employees
“Developing a novel vesico-amniotic shunt to treat fetal lower urinary tract obstruction”
Department of Health and Human Services · Phase Phase II
Cortechs Labs, Inc.
SAN DIEGO, CA · 19 employees
“Quantification of ARIA During the Treatment of Alzheimer's Patients”
Department of Health and Human Services · Phase Phase II
Cache DNA, Inc.
San Carlos, CA · 6 employees
“SBIR Phase II: Rapid Ambient Preservation using Thermosets for Optimized Protection of Biomolecules”
National Science Foundation · Phase Phase II
ANALATOM INCORPORATED
SANTA CLARA, CA · 7 employees
“Physics-Informed Synthetic Sonar Data Generation using Deep Diffusion Models”
Department of Defense · Phase Phase I
INTERLOG CORPORATION
ANAHEIM, CA · 25 employees
“C-VIS: Color Vision Integrated SWIR for Multi-Spectral Imaging and Navigation”
Department of Defense · Phase Phase I
SURFACE OPTICS CORPORATION
SAN DIEGO, CA · 36 employees
“Dual-Band, Color Visible (VIS) and Short-Wave Infrared (SWIR) Camera”
Department of Defense · Phase Phase I
CRITICAL INNOVATIONS LLC
LAWNDALE, CA · 31 employees
“Aid-Tex Wearable e-Textile System for Control of Junctional and Extremity”
Department of Defense · Phase Phase I/Phase II
Terra Quantum Falcon Inc.
SAN FRANCISCO, CA · 20 employees
“Ultra-Secure, Post-Quantum Communications and Encryptions (US-PQC/E)”
Department of Defense · Phase Phase II
ASTRO MECHANICA CORP
SAN FRANCISCO, CA · 17 employees
“Revolutionizing Air Dominance: The Duality Engine's Role in Future Combat Aircraft”
Department of Defense · Phase Phase II
BEACON AI INC
SAN CARLOS, CA · 14 employees
“AI-Enhanced Adaptive Risk Analytics and Automated Briefing Product for Military and Commercial Aviation”
Department of Defense · Phase Phase II
QUASAR FEDERAL SYSTEMS, INC.
San Diego, CA · 12 employees
“Compact Underwater Electromagnetic Sensor System (CUES) with Internal Data Logging”
Department of Defense · Phase Phase I
VERNE INC
SAN FRANCISCO, CA · 19 employees
“Delivered power with containerized cryo-compressed hydrogen systems”
Department of Defense · Phase Phase II
EXPLORATION LABORATORIES LLC
LONG BEACH, CA · 10 employees
“Space Exploration Resource Vehicle for in-space Servicing, Assembly and Manufacturing (SERVSAM)”
Department of Defense · Phase Phase II
ACROSS AI, INC
SAN FRANCISCO, CA · 0 employees
“SBIR Phase I: Revolutionizing Enterprise Processes with Automated Logical Reasoning Across Unstructured Data”
National Science Foundation · Phase Phase I
XSITE LLC
SAN DIEGO, CA · 34 employees
“XSITE - N251-004 - Kill Web Conceptual Modeling for Wargaming”
Department of Defense · Phase Phase I
INERTIALWAVE INC
TORRANCE, CA · 5 employees
“An Application-Specific DTDSM ADC Using State-of-The-Art Circuit Techniques for Magnetic and Electropotential Sensors”
Department of Defense · Phase Phase I
MOMENTUS SPACE LLC
SAN JOSE, CA · 81 employees
“Low Cost Multispectral RPO Sensor Suite”
Department of Defense · Phase Phase II
Syncanica Bio, Inc.
Sacramento, CA · 2 employees
“Pseudocannabinoids for mitigation of substance use disorder”
Department of Health and Human Services · Phase Phase I
THIRD ELEMENT BIO INC.
SAN DIEGO, CA · 5 employees
“Development of a RUNX1 modulator to slow cognitive decline in Alzheimer's disease”
Department of Health and Human Services · Phase Phase I
Biolinq Incorporated
SAN DIEGO, CA · 110 employees
“Wearable Metabolic Sensor for Monitoring of Lactate and Glucose for People with Diabetes”
Department of Health and Human Services · Phase Phase II
ALBIREO TECHNOLOGIES LLC
PORTER RANCH, CA · 2 employees
“Multi-Modal X-ray Inspection System”
Department of Defense · Phase Phase II
GBL SYSTEMS CORPORATION
CAMARILLO, CA · 61 employees
“Next Generation Open Mission System (NOMS) Weapon Integration Support”
Department of Defense · Phase Phase II
ELECTRONIC BIOSCIENCES, INC.
SAN DIEGO, CA · 12 employees
“SpinSeq”
Department of Health and Human Services · Phase Phase I
PROTEIN FLUIDICS INC
Redwood City, CA · 3 employees
“High-throughput Organoid Screening Platform for Investigating Novel Traumatic Brain Injury Therapeutics”
Department of Defense · Phase Phase I
SPACE FOUNDRY INC
SAN JOSE, CA · 3 employees
“Plasma Jet Printing of Lead-salt based MWIR Photoconductive Detectors”
Department of Defense · Phase Phase I
SPZ Technologie, LLC
Los Angeles, CA · 3 employees
“Platelet Contractility Imaging Analyzer (PCIA)”
Department of Defense · Phase Phase I
LUMINA MEDICAL LLC
Culver City, CA · 1 employee
“Motorized Girth Adjustable Dilator with Dilation and Pressure Measurement for Anorectal Disorders, Designed to Improve Patient Adherence to ”
Department of Health and Human Services · Phase Phase I
Vellum Biotechology, Inc.
PALO ALTO, CA · 8 employees
“Developing a New Nucleic Acid Extraction Technology to Enable High Quality DNA Sequencing for Formalin Fixed Paraffin Embedded Tissue Sample”
Department of Health and Human Services · Phase Phase II
ARTYC PBC
Fremont, CA · 7 employees
“STTR Phase I: A Novel Magnetocaloric Cooling System for the Cold Chain”
National Science Foundation · Phase Phase I
SPATIAL GENOMICS, INC.
PASADENA, CA · 9 employees
“Next generation spatial genomics tools for the human brain”
Department of Health and Human Services · Phase Phase II
STRESS THERAPEUTICS, INC.
SAN DIEGO, CA · 2 employees
“Lead Optimization of a Therapeutic Candidate for Alzheimer’s Disease”
Department of Health and Human Services · Phase Phase I
Tetac Inc.
MONTEREY, CA · 4 employees
“APOBS Modernization”
Department of Defense · Phase Phase II
ATOMNAUT INC.
SAN FRANCISCO, CA · 1 employee
“SBIR Phase I: In situ vitrification to unlock routine atomic-scale imaging of biomolecule structure and chemistry in three dimensions”
National Science Foundation · Phase Phase I
3VO MEDICAL, INC
LOS ANGELES, CA · 3 employees
“SBIR Phase I: Feasibility of a Novel Minimally Invasive Labor Augmentation System for Stage I Labor”
National Science Foundation · Phase Phase I
Nanodesk, LLC
FREMONT, CA · 3 employees
“SBIR Phase I: Software for Collaborative End-to-End Development of DNA Nanostructures”
National Science Foundation · Phase Phase I
Bridge Platform Holdings, INC.
Woodside, CA · 50 employees
“Optimizing Remote Pre-Accession Training for AFSPECWAR using BridgeAthletic with Garmin Integration”
Department of Defense · Phase Phase II
XCELERIUM INC
IRVINE, CA · 20 employees
“A Low-Power, Dynamically Reconfigurable Scalable Array Processor (DRSAP) for Software-Defined Universal Terminals with Integrated RF”
Department of Defense · Phase Phase II
RHOMAN AEROSPACE CORPORATION
MARINA DEL REY, CA · 5 employees
“Software Deployable GPS-Denied UAV Autonomy: Alt-PNT via Software Upload, No-Emit, No Pre-Loaded Terrain Maps, Scalable Across UAV Platforms”
Department of Defense · Phase Phase I/Phase II
FREEDOM FLIGHT WORKS, INC.
San Diego, CA · 10 employees
“Powered Parafoil - Self Propelled Charging System (PP-SPCS)”
Department of Defense · Phase Phase II
Oorjahvaan
vacaville, CA · 1 employee
“Revitalizing the US Innovation Triangle digitally using Omtrium”
Department of Defense · Phase Phase II
DeepSat
North Hollywood, CA · 3 employees
“DeepSat - DAF X25.5 CSO Air Force Direct-to-Phase II (D2P2)”
Department of Defense · Phase Phase II
KYTE DYNAMICS, INC.
Los Angeles, CA · 3 employees
“Low-signature, Dual-stage UAS for Precision Resupply and ISR in Contested, GPS-Denied Environments”
Department of Defense · Phase Phase II
Grid Aero, Inc.
San Leandro, CA · 20 employees
“Mission Automation of Low Cost Group 5 UAS for Contested Logistics”
Department of Defense · Phase Phase II
TRABUS
SAN DIEGO, CA · 35 employees
“SEPP Networks - Waveform Agility using Spectrally Efficient Peer-to-Peer Communications Technology”
Department of Defense · Phase Phase I/Phase II
SNORKEL AI INC
REDWOOD CITY, CA · 98 employees
“Revolutionizing Aircraft Survivability Analysis with AI-Driven Data Extraction”
Department of Defense · Phase Phase II
ARRAY LABS, INC.
PALO ALTO, CA · 25 employees
“Development of Robust All-Weather 3D RADAR Algorithms with Immediate Warfighter Benefit”
Department of Defense · Phase Phase II
NEUROFIT, INC.
MOUNTAIN VIEW, CA · 6 employees
“Brain Health Monitoring Platform”
Department of Defense · Phase Phase II
BeeSafe Labs, LLC
San Diego, CA · 1 employee
“SBIR Phase I: Counteracting Social Engineering Attacks with Honeypot LLM Chatbots”
National Science Foundation · Phase Phase I
Flyby Robotics
Los Angeles, CA · 10 employees
“Non-Emitting Autonomous ISR Mission Capability With AI Object Identification Onboard Unmanned Aerial System”
Department of Defense · Phase Phase II
RATTAN LIFE SCIENCE INC
SUNNYVALE, CA · 4 employees · woman-owned
“SBIR Phase II: Engineered Induced Thymic Epithelial Cells for Novel T Cell Immunotherapies”
National Science Foundation · Phase Phase II
ADDITIVE SPACE TECHNOLOGIES, INC.
BERKELEY, CA · 2 employees
“Single Pallet Additive Manufacturing Cell for Rapid Deployment and Part Manufacturing”
Department of Defense · Phase Phase II
AURIGA SPACE, INC
Garden Grove, CA · 11 employees · woman-owned
“Auriga’s Electromagnetic Testbed for Hypersonic Experimentation and Rapid development (AETHER)”
Department of Defense · Phase Phase I/Phase II
COMPOSABL, INC
MARTINEZ, CA · 5 employees
“AI-Driven Wargaming for Strategic Decision-Making at Air University”
Department of Defense · Phase Phase II
SPIRO ROBOTICS, INC
Hayward, CA · 12 employees
“Handheld Robotic Device for Difficult Tracheal Intubation”
Department of Defense · Phase Phase I/Phase II
OSEL, INC.
MOUNTAIN VIEW, CA
“Novel Antimicrobial Approach to Treat Chemoradiation Resistant Cervical Cancer by Selectively Inhibiting Lactobacillus iners”
Department of Health and Human Services · Phase Phase I
RESCAN INC
MENLO PARK, CA · 12 employees
“REVOLUTIONIZING AIR FORCE INFRASTRUCTURE WITH AI-POWERED 3D DIGITAL TWINS”
Department of Defense · Phase Phase II
HEDGEFOG RESEARCH INC.
SAN PEDRO, CA · 10 employees
“Contact Lens Integrated Physiological Sensors”
Department of Defense · Phase Phase I/Phase II
Reflect Orbital Inc.
Hawthorne, CA · 70 employees
“Satellite Technology Delivering On-Demand Lighting for Military Operations and Uninterrupted Solar Power for Energy Production”
Department of Defense · Phase Phase II
INFORMATION SYSTEMS LABORATORIES INC
POWAY, CA · 72 employees
“Threat Emitter Omniscience Suite (THEOS)”
Department of Defense · Phase Phase II
COFACTOR SYSTEMS INC.
SANTA BARBARA, CA · 30 employees
“Shiftwave: A Deployable Solution for Rapid Recovery, Stress Reduction, and Enhanced Human Performance for Air Force Operational Support Team”
Department of Defense · Phase Phase II
Noctrix Health
PLEASANTON, CA · 72 employees
“Developing closed-loop tonic motor activation therapy for treatment of refractory restless legs syndrome”
Department of Health and Human Services · Phase Phase II
PLEIOGENIX INC
CARLSBAD, CA · 2 employees
“An innovative, non-thiazolidinedione pan-PPAR agonist therapeutic for alcoholic hepatitis: IND-enabling safety and toxicological evaluation”
Department of Health and Human Services · Phase Phase II
HEPATX CORPORATION
PALO ALTO, CA · 4 employees
“Development of a proteomic assay for monitoring transplanted cells and tissues”
Department of Health and Human Services · Phase Phase I
IOTAI INC
FREMONT, CA · 20 employees
“All Domain Tracking Kits”
Department of Defense · Phase Phase II
3DT HOLDINGS, LLC
SAN DIEGO, CA · 8 employees
“Software-guided Operative Planning of MitraClip Placement”
Department of Health and Human Services · Phase Phase II
DFUSION INC.
SCOTTS VALLEY, CA · 8 employees · woman-owned
“Simulation for Environmental Exposure Education (S3E): A Serious Game Platform for Environmental Health Literacy”
Department of Health and Human Services · Phase Phase I/Phase II
Endura Therapeutics, Inc.
South San Francisco, CA · 3 employees
“SBIR Phase I: Multiplexed High Throughput Discovery of Functional RNA-Targeting Small Molecules Via Next-Generation Sequencing”
National Science Foundation · Phase Phase I
Syntopa Inc.
EL SOBRANTE, CA · 6 employees
“SBIR Phase I: Enhanced Rock Weathering through Gene Editing of Soil Microorganisms”
National Science Foundation · Phase Phase I
Castle Global, Inc
San Francisco, CA · 250 employees
“Enhancing Video Conferencing Security To Prevent Digital Injection Attacks”
Department of Homeland Security · Phase Phase I
NANOTECH ENERGY INC
CHICO, CA · 45 employees
“Next Generation 21700 Battery Cells for 6T Batteries”
Department of Defense · Phase Phase II
VIRTUALITICS INC
PASADENA, CA · 85 employees
“Generating Optimized RSP Loading Plans using modern AI-based Constraint Solvers”
Department of Defense · Phase Phase II
Rincell Corporation
Sunnyvale, CA · 10 employees
“Strengthening Army Capabilities: Ultra-High Energy 18650 Batteries for Tactical Power Needs”
Department of Defense · Phase Phase II
AAIIT LLC
San Diego, CA · 3 employees
“Protein display drug ANDI reduces asthmatic airway hyperreactivity”
Department of Health and Human Services · Phase Phase I
MANTIS COMPOSITES INC
SAN LUIS OBISPO, CA · 10 employees
“3D Printed Continuous Fiber Ablative Propulsion Elements”
Department of Defense · Phase Phase II
JACARANDA BIOSCIENCES, INC.
SAN FRANCISCO, CA · 2 employees
“eiF2B Activators to Treat Noise-Induced Hearing Loss”
Department of Health and Human Services · Phase Phase II
Submarine Scientific LLC
San Francisco, CA · 3 employees · woman-owned
“SBIR Phase I: Automatically Configurable Graphical Processing Unit Optimized Ocean Carbon Modeling Platform”
National Science Foundation · Phase Phase I
HILL ENGINEERING LLC
RANCHO CORDOVA, CA · 22 employees
“Nondestructive Evaluation for Assessing Cold Worked Countersunk and/or Filled Fastener Holes in Titanium and Steel Aerospace Alloys”
Department of Defense · Phase Phase II
VENATOR SOLUTIONS, LLC
SAN DIEGO, CA · 17 employees
“Next Generation Autonomous Tracking”
Department of Defense · Phase Phase II
ALKEMIX CORPORATION
LAGUNA HILLS, CA · 6 employees
“TPS for Hypersonic Applications”
Department of Defense · Phase Phase II
SENSYDIA CORPORATION
LOS ANGELES, CA · 9 employees
“A non-invasive, automated platform for hemodynamic assessment of patients at risk of heart failure or pulmonary hypertension”
Department of Health and Human Services · Phase Phase II
UTOPIACOMPRESSION,CORPORATION
Los Angeles, CA · 18 employees
“Intelligent Visual System for Maritime Applications”
Department of Defense · Phase Phase II
Scout AI Inc.
Sunnyvale, CA · 21 employees
“Scout AI - Mission Complete Unmanned Ground Vehicle Systems”
Department of Defense · Phase Phase II
NEXTGENJANE INC
OAKLAND, CA · 6 employees
“Performance evaluation of a non-invasive menstrual test for endometriosis in infertility patients”
Department of Health and Human Services · Phase Phase II
VDF Industries Inc
BURLINGAME, CA · 1 employee
“Phonocath - An endovascular medical device to objectively evaluate Pulsatile Tinnitus”
Department of Health and Human Services · Phase Phase I
AEROSOL DYNAMICS INC
BERKELEY, CA · 7 employees
“Coupled Aerodynamic and Optical Sizing for Coarse Particles”
Department of Energy · Phase Phase II
XIA LLC
OAKLAND, CA · 16 employees
“Improved electronics for BeEST sterile neutrino search”
Department of Energy · Phase Phase II
SIGRAY, INC.
CONCORD, CA · 85 employees
“Development of Advanced X-ray Emission Spectrometer”
Department of Energy · Phase Phase II
Q-FLEX INC
SANTA ANA, CA · 26 employees · woman-owned
“Development of Super Conducting Low Radioactivity flexible cables and circuitry (ULB-SSC)”
Department of Energy · Phase Phase II
SiLi-ion Inc.
Yorba Linda, CA · 2 employees
“A Plasma-Enabled Approach to Next-Generation Energy Storage Materials”
Department of Energy · Phase Phase II
SOMEWEAR LABS, INC.
SAN FRANCISCO, CA · 31 employees
“Somewear Labs Non-Attributable Mobile Mesh and Satcom Network Devices”
Department of Defense · Phase Phase II
Mobilio Co.
SAN FRANCISCO, CA · 10 employees
“Autonomous Component Replacement Engine for Army Equipment Sustainment”
Department of Defense · Phase Phase I/Phase II
ATTOLLO ENGINEERING, LLC
CAMARILLO, CA · 60 employees
“Optical Proximity Sensor for APKWS”
Department of Defense · Phase Phase I/Phase II
INSPIRD INC.
MISSION VIEJO, CA · 12 employees
“Toolkit for Practical, Accurate, Secure, and Reliable RAG”
Department of Defense · Phase Phase I
ENDOMET BIOSCIENCES, INC
IRVINE, CA · 6 employees · woman-owned
“Novel, Non-hormonal Therapeutic for Endometriosis”
Department of Health and Human Services · Phase Phase II
Cellecho Inc.
Irvine, CA · 0 employees
“SBIR Phase I: A Microprocessor for Complex, Multidimensional Cell Reprogramming: Acoustic-Electric Micro-Vortices Technology for Precise, Se”
National Science Foundation · Phase Phase I
LEWIZ COMMUNICATIONS, INC.
SUNNYVALE, CA · 10 employees
“Fast, Self-Recovery, Fully Rad-Hard FPGA Chip”
Department of Defense · Phase Phase II
SWIFT SOLAR INC
SAN CARLOS, CA · 38 employees
“Precursor Impurity Control for Stable Perovskite Tandem Photovoltaic Modules”
Department of Defense · Phase Phase II
INVIZYNE TECHNOLOGIES INC
MONROVIA, CA · 13 employees
“Bio-Click: A cell-free high-throughput platform for the engineering of enzymatic group transfer reactions”
Department of Health and Human Services · Phase Phase I
TRESTLE OPTICS LLC
IRVINE, CA · 6 employees
“In vitro metabolite profiling with vibrational phase-contrast imaging”
Department of Health and Human Services · Phase Phase I
PARTILLION BIOSCIENCE CORP
LOS ANGELES, CA · 12 employees
“Scaling function-first antibody discovery leveraging memory B cells”
Department of Health and Human Services · Phase Phase II
NURAVAX, INC.
IRVINE, CA · 9 employees
“Evaluate the Safety, Tolerability, and Immunogenicity of Adjuvanted Preventive Dual Aβ/tau Vaccine, Duvax in Healthy Volunteers”
Department of Health and Human Services · Phase Phase I
LEBRUN LABS LLC
ANAHEIM, CA · 5 employees
“An In Chemico Test to Identify Dermal Corrosives”
Department of Health and Human Services · Phase Phase II
SE-RAN L.L.C.
Cupertino, CA · 5 employees
“O244-P002-0117 Extending the Open-RAN for 5G and Beyond Autonomous Fault and Security Posture Management”
Department of Defense · Phase Phase I
JULIA JEAN, LLC
IRVINE, CA · 4 employees · woman-owned
“SBIR Phase I: Novel Cold Cathode E-Beam Sources for Advancing Semiconductor Manufacturing”
National Science Foundation · Phase Phase I
Core Biotherapeutics, Inc
Ladera Ranch, CA · 2 employees
“SBIR Phase I: Determination of the Mechanisms Driving Diseases at the Molecular Network Level to Develop Disruptive Drug Candidates”
National Science Foundation · Phase Phase I
Synthefy, Inc.
San Diego, CA · 3 employees
“Synthefy: Multi-Modal Diffusion Models for Synthetic RF Time Series”
Department of Defense · Phase Phase II
LUNA MANUFACTURING LLC
San Francisco, CA · 1 employee
“Additive Manufacturing High Density Materials with Locally Controllable Deformation Properties”
Department of Defense · Phase Phase I
SURVEY GENOMICS, INC.
BERKELEY, CA · 6 employees
“Pioneering assays for spatially-resolved single-cell multiomics”
Department of Health and Human Services · Phase Phase II
DARK FISSION SPACE SYSTEMS, INC.
Huntington Beach, CA · 3 employees
“DARKFORCE - A Fast Orbital Transfer Vehicle for Dynamic Space Operations”
Department of Defense · Phase Phase II
Evidation Health, Inc.
San Mateo, CA · 96 employees
“Research and Engagement on Substance use Harnessing Awareness and Personalized Education (RESHAPE)”
Department of Health and Human Services · Phase Phase I
ChemRegen Inc
San Diego, CA · 5 employees
“iPSC-derived human neurons and OUD medications development”
Department of Health and Human Services · Phase Phase I
Ali Innovation Inc
Lake Forest, CA · 1 employee
“Reentry Event Detection and Prediction using Deep Learning-based Satellite Constellation Analysis”
Department of Defense · Phase Phase I
WILSON EAGLE LP
SAN CLEMENTE, CA · 4 employees
“Integrating the Advanced Correlator-Navy (ACOR-N) Data Fusion Processor into the Command and Control Experimentation (C2X) Capability to Enh”
Department of Defense · Phase Phase II
PETcoil, Inc.
SUNNYVALE, CA · 4 employees
“Commercialization Readiness for a Portable PET Insert System for Simultaneous TOF-PET and MR Brain Imaging”
Department of Health and Human Services · Phase Phase II
NU-TREK, INC.
SAN DIEGO, CA · 9 employees · woman-owned
“Low SWAP Thermal ROIC in an Advanced Node”
Department of Defense · Phase Phase I/Phase II
ARTIUM TECHNOLOGIES, INC.
SUNNYVALE, CA · 13 employees
“High-Efficiency High-Resolution Characterization of Flow Velocity, Median Volume Diameter, and Liquid Water Content Uniformity in Simulated ”
Department of Defense · Phase Phase II
DIRAC SOLUTIONS, INC.
PLEASANTON, CA · 9 employees
“Secure UWB Communications for Aircrew Physiological Monitoring”
Department of Defense · Phase Phase II
RC INTEGRATED SYSTEMS LLC
TORRANCE, CA · 5 employees · woman-owned
“Hybrid Integrated Slipring Capsule”
Department of Defense · Phase Phase II
GENTIAM CONSULTING LLC
Oakland, CA · 3 employees
“Universal Hybrid Powertrain Controller for Integrated Hybrid and Electric Powertrains”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I
SCALED POWER INC
SAN FRANCISCO, CA · 6 employees
“Lightweight Turbogenerator for Hybrid-Electric Propulsion Systems”
Department of Defense · Phase Phase I
Intrinsic Power, Inc.
Los Angeles, CA · 5 employees
“The Ruggedized Power export Module (RPeM) for Holistically Supplementing Army Power Needs in Austere Environments Through EVs and Solar Gene”
Department of Defense · Phase Phase I
JUMPCODE GENOMICS INC
SAN DIEGO, CA · 10 employees
“CRISPR-based depletion method for resolving pseudogene contamination in Next Generation Sequencing (NGS) based genetic testing”
Department of Health and Human Services · Phase Phase I
Thaero LLC
WESTLAKE VILLAGE, CA · 5 employees
“Active Materials for Protection Sustainment (AMPS)”
Department of Defense · Phase Phase I
Elite Neuro Inc.
Pasadena, CA · 1 employee
“STTR Phase I: Enhancing Cognitive Performance Through a Scalable Virtual Reality Platform”
National Science Foundation · Phase Phase I
AESCULATECH INC
LOS ANGELES, CA · 8 employees · woman-owned
“Humidifeye Plug for Dry Eye Disease”
Department of Health and Human Services · Phase Phase II
Sonomotion Inc.
San Mateo, CA · 10 employees
“Break Wave lithotripsy to fragment large kidney stones”
Department of Health and Human Services · Phase Phase I
CONFIDENCIAL INC
MENLO PARK, CA · 20 employees
“Confidencial for Advanced Data Integrity and Control Methods”
Department of Defense · Phase Phase I
GIANT BioSystems Inc.
PASADENA, CA · 6 employees · woman-owned
“SBIR Phase I: High-Throughput AST Using Gradient-Based Microfluidic”
National Science Foundation · Phase Phase I
ZIVA CORPORATION
SAN DIEGO, CA · 7 employees
“Precision Indirect Fire Navigation (ODIN)”
Department of Defense · Phase Phase II
NEXUS PHOTONICS INC
GOLETA, CA · 15 employees
“Application specific PICs operating around 780 nm towards MPWs”
National Aeronautics and Space Administration · Phase Phase II
REDONDO OPTICS, INC.
REDONDO BEACH, CA · 6 employees
“Low Cost, High-Throughput, Dense-Fiber Channel Optical Interrogator Based Photonic Integrated Circuits (PIC) Microchip Technology”
Department of Defense · Department of Energy · Phase Phase I
BRECHTEL MANUFACTURING, INC.
HAYWARD, CA · 17 employees
“Aerosol Size Distribution Measurements for Marine Platforms”
Department of Energy · Phase Phase I
IBP USA Group Inc.
San Pedro, CA · 1 employee
“30 nm thick silicon photodiodes with 100% internal quantum efficiency for VUV spectroscopy of tokamak plasmas”
Department of Energy · Phase Phase I
ROCHESTER SCIENTIFIC LLC
EL CERRITO, CA · 2 employees
“Improvements in optical metrology for high-performance variable-line-spacing x-ray gratings”
Department of Energy · Phase Phase I
PARTOW TECHNOLOGIES LLC
CARLSBAD, CA · 3 employees
“Fiber-optic electro-optic sensors for non-destructive electron beam diagnostics”
Department of Energy · Phase Phase I
Controlx, Inc.
Santa Clara, CA · 5 employees
“Resilient Robotic Automation: Enhancing Efficiency and Safety in Aircraft Servicing”
Department of Defense · Phase Phase I
Stellar Engiine
Los Altos, CA · 2 employees
“SBIR Phase I: Advanced PEALD Processing Technology using Nanosecond Pulse Power”
National Science Foundation · Phase Phase I
APEX TECHNOLOGY, INC.
LOS ANGELES, CA · 164 employees
“APEX STRATFI Proposal”
Department of Defense · Phase Phase II
Archetype AI Inc
San Diego, CA · 7 employees
“Artificial Intelligence Pipeline for Infrared Thermography, Ultrasonic, Visual and other Unconventional Data for Non-Destructive Inspection ”
Department of Defense · Phase Phase I
FORMALLOY TECHNOLOGIES INC
SPRING VALLEY, CA · 21 employees · woman-owned
“Advanced Robotic Automation for Repair, Metal Forming, and Welding via Directed Energy Deposition (DED)”
Department of Defense · Phase Phase I
ALTEX TECHNOLOGIES CORPORATION
SAN JOSE, CA · 15 employees
“Desulfurizer for JP-8 Fueled Tier 4 Engines (JP8T4)”
Department of Defense · Phase Phase I
QUANTUM APPLIED SCIENCE & RESEARCH INC
SAN DIEGO, CA · 13 employees
“Cognitive Health Impact and Physiological Sensors (CHIPS) Helmet, Phase II”
Department of Defense · Phase Phase II
REKOVAR INC
LAGUNA NIGUEL, CA · 9 employees
“Wireless Wearable with AI Analytics for Monitoring Neonatal Abstinence Syndrome (NAS)”
Department of Health and Human Services · Phase Phase I
ARGOSMD, INC.
Studio City, CA · 1 employee
“Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatment”
Department of Health and Human Services · Phase Phase I
XCELLASSAY, INC
SAN FRANCISCO, CA · 4 employees · woman-owned
“Meeting the cost and privacy demands for detecting Anabolic Androgenic Steroid doping in youth athletics with rationally designed nuclear re”
Department of Health and Human Services · Phase Phase I
Out of the Fog Research LLC
Mountain View, CA · 9 employees
“CRES for HF”
Department of Defense · Phase Phase II
ELROY AIR INC
BYRON, CA · 60 employees
“Chaparral Airdrop Capability Development”
Department of Defense · Phase Phase II
COLLABORATIVE ROBOTICS INC.
SANTA CLARA, CA · 59 employees
“Development and Certification of Explosion-Proof Collaborative Robots: A Pathway for Modernizing the Army’s Energetic Industrial Base”
Department of Defense · Phase Phase I
KRTKL INC.
SAN FRANCISCO, CA · 10 employees
“Spectral Awareness for Autonomous and Remotely Operated Systems”
Department of Defense · Phase Phase II
Doodle Labs LLC
MARINA DEL REY, CA · 10 employees
“Adaptive Ultra-Wideband SDRH for Tactical Communications”
Department of Defense · Phase Phase II
EPIRUS, INC
TORRANCE, CA · 182 employees
“DC Power Controller (DCPC) for Tactical Microgrid”
Department of Defense · Phase Phase I
Hunted Labs LLC
LONG BEACH, CA · 3 employees · woman-owned
“Hunted Labs - ACE software supply chain security data analytics to improve resiliency”
Department of Defense · Phase Phase II
NORTHWOOD SPACE CORP.
Torrance, CA · 45 employees
“Ultra-wideband Arrays for Proliferated Satellite Communications”
Department of Defense · Phase Phase I
AEROCHARGE INC.
LOS ANGELES, CA · 6 employees
“Scalable UAS Persistence using Enhanced RF power Beaming (SUPERB)”
Department of Defense · Phase Phase I
FEMTOSENSE, INC.
SAN BRUNO, CA · 25 employees
“Low-Power Sparse AI Processing for Enhanced ISR Communications with Femtosense’s SPU-001 Chip”
Department of Defense · Phase Phase I
MonuMedical LLC
PENRYN, CA · 5 employees
“Prolonged Field Care with the MiniFuser Infusion Device”
Department of Defense · Phase Phase I
CELERIS SYSTEMS, INC.
ANAHEIM, CA · 60 employees
“Predictive Analytics to Maintain Program Development Speed and Reduce Risk on Test Resources”
Department of Defense · Phase Phase I
UBIQUITY ROBOTICS, INC.
SAN JOSE, CA · 40 employees
“MAGNI ROBOT: Mobile Autonomous Ground Navigation Integrated Robot for Optimizing Base Operational Tasks”
Department of Defense · Phase Phase I
KYNDI INC
SAN MATEO, CA · 19 employees
“Empowering Air Force with Large Language Model-powered Agentic RAG”
Department of Defense · Phase Phase I
SOPHIA SPACE, INC.
PASADENA, CA · 15 employees
“Large Scale Data Centers in Space”
Department of Defense · Phase Phase I
RE:ORBITAL INC.
Los Angeles, CA · 1 employee
“Bodyguard - Deployable System for ASAT Defense”
Department of Defense · Phase Phase I
Eclipse Bioinnovations, Inc.
SAN DIEGO, CA · 10 employees
“eMOA: A Multi-Omic Service for Mechanism of Action Determination in Drug Screening”
Department of Health and Human Services · Phase Phase II
SWIRLABS CORP
LA CANADA FLINTRIDGE, CA · 3 employees
“Development of Analog Mixed Signal IP Library ? for IR FPA ROIC Sensors?”
Department of Defense · Phase Phase I
CUSTOMWEATHER, INC.
Mill Valley, CA · 5 employees
“Tactical Weather Modeling System (TEMS)”
Department of Defense · Phase Phase I
ATOMIC SEMI, INC
PALO ALTO, CA · 25 employees
“Domestic Semiconductor Fab for Fast, Agile, and Inexpensive Chipset Production”
Department of Defense · Phase Phase I
DTP THERMOELECTRICS LLC
Pasadena, CA · 4 employees
“Advancing Distributed Transport Properties Thermoelectrics for Solid-State Cryo-Cooling for Air Force IR Sensors and Optical Packages”
Department of Defense · Phase Phase I
Kitt Bio, Inc
Los Angeles, CA · 17 employees
“FlyKitt: Jet Lag Elimination”
Department of Defense · Phase Phase I
ZEROAVIA, INC
HOLLISTER, CA · 120 employees
“Feasibility Study for Integrating Hydrogen Propulsion and Aircraft Automation in a Cessna Caravan”
Department of Defense · Phase Phase I
Waveye, Inc.
PALO ALTO, CA · 5 employees
“Multi-Agent Robotic System In Dynamic Environments With AI-Driven Networked 4D Imaging Radars Based Perception System”
Department of Defense · Phase Phase I
Corellian Energy, LLC
SACRAMENTO, CA · 15 employees
“Battle-Ready Data: Miniaturizing Cloud Power for Tactical Superiority”
Department of Defense · Phase Phase I
Selas Energy, LLC
SACRAMENTO, CA · 15 employees
“EnergyOS: Transforming Legacy Energy into Smart, Resilient Grids”
Department of Defense · Phase Phase I
Knightscope, Inc.
Mountain View, CA · 30 employees
“Autonomous Public Safety Solutions for U.S. Air Force Installation Security Needs”
Department of Defense · Phase Phase I
TERRAFERMA FOODS, INC.
SAN FRANCISCO, CA · 2 employees · woman-owned
“SBIR Phase I: A novel platform for accelerated strain development for precision fermentation”
National Science Foundation · Phase Phase I
DIGIBEAM CORPORATION
SAN JUAN CAPISTRANO, CA · 9 employees
“Surface Anti-material Weapon”
Department of Defense · Phase Phase I
TONIC AI, INC.
San Francisco, CA · 69 employees
“Deidentifying Personally Identifiable Information (PII) for LLM Ingestion and RAG Applications”
Department of Defense · Phase Phase I
TRAVERSE AERO CORPORATION
RICHMOND, CA · 5 employees
“Orca - Hybrid-electric eVTOL cargo drone”
Department of Defense · Phase Phase I
STARLIGHT CARDIOVASCULAR INC
SAN DIEGO, CA · 6 employees
“DUCTUS ARTERIOSUS STENT TO IMPROVE CONGENITAL HEART DEFECT MORTALITY”
Department of Health and Human Services · Phase Phase II
Osem Fluidics Inc
ALHAMBRA, CA · 4 employees
“Three-Dimensional Spatio-Temporal Control of Lipid Nanoparticle Manufacturing for Improved Nucleic Acid Delivery”
Department of Health and Human Services · Phase Phase I
VANNEVAR LABS INC
Palo Alto, CA · 207 employees
“NASIC GXK STRATFI Proposal - OCR enabled intelligence”
Department of Defense · Phase Phase II
SLINGSHOT AEROSPACE INC
EL SEGUNDO, CA · 148 employees
“Slingshot RAPTOR”
Department of Defense · Phase Phase II
XTELLIGENT INC
LOS ANGELES, CA · 21 employees
“Enhancing Base Security and Efficiency with an Advanced Intelligent Traffic Management System”
Department of Defense · Phase Phase I
A.T.E. SOLUTIONS, INC.
EL SEGUNDO, CA · 3 employees
“AI-Assisted TPS Development and Sustainment”
Department of Defense · Phase Phase I
Deep Media, Inc
OAKLAND, CA · 20 employees
“Advanced Machine Translation System for Low-Resource Languages with ATAK Integration”
Department of Defense · Phase Phase II
TURION SPACE CORP
IRVINE, CA · 120 employees
“Enhancing Battlespace Awareness Utilizing Multi-Payload SDA Satellites and Real-Time Command & Control”
Department of Defense · Phase Phase II
DARE BIOSCIENCE, INC.
SAN DIEGO, CA · 24 employees
“A first-in-class product for the clearance of high-risk human papillomaviruses”
Department of Health and Human Services · Phase Phase II
ANTARIS, INC.
LOS ALTOS, CA · 12 employees
“Antaris TrueTwin: A Cognitive Digital Twin solution for Autonomous Target Discrimination”
Department of Defense · Phase Phase I
Symmetry Wood, PBC
Los Angeles, CA · 2 employees
“Upcycling Food Waste into Bacterial nanocellulose to Create High-Performance Dimensional Wood”
Environmental Protection Agency · Phase Phase I
PACIFIC RECLAIMED LUMBER & SUPPLY, SPC
SEBASTOPOL, CA · 0 employees · woman-owned
“Scaling Reclaimed Lumber Sales & Procurement Through Web and App-Based Technology”
Environmental Protection Agency · Phase Phase I
AGTEC INNOVATIONS, INC.
LOS ALTOS, CA · 3 employees
“SMARTP Fertilizer - The Environment-Friendly Phosphate Alternative”
Environmental Protection Agency · Phase Phase I
SYNVIVIA, INC.
EMERYVILLE, CA · 3 employees
“Platform for Optimizing Yield and Quality of Therapeutic AAV Vector Manufacturing via Synthetic Helper Genes”
Department of Health and Human Services · Phase Phase II
EPISYS SCIENCE INC
POWAY, CA · 86 employees
“STRATFI SBIR Sequential Phase II”
Department of Defense · Phase Phase II
CARBON TECHNOLOGY INC
SAN CLEMENTE, CA · 3 employees
“10x Threat Detection Sensitivity Deployed in Battlefield Systems”
Department of Defense · Phase Phase I
Design West Technologies, Inc.
Tustin, CA · 200 employees
“Algorithms for Modular Remote Expendable Sensor Array”
Department of Defense · Phase Phase I
BRAINCHIP, INC
LAGUNA HILLS, CA · 76 employees
“Low C-SWAP Neuromorphic Radar Classification”
Department of Defense · Phase Phase II
MAYACHITRA, INC.
SANTA BARBARA, CA · 10 employees
“GUARDIAN: Generating Understanding and Accountability in Robust Detection with Directed Energy Insights and Analysis of Neural Collapse”
Department of Defense · Phase Phase I
LAUNCHPOINT ELECTRIC PROPULSION SOLUTIONS, INC.
GOLETA, CA · 31 employees
“Advancing Rotorcraft Design Through Innovative Electric Motor and Thermal Management Technologies”
Department of Defense · Phase Phase I
SENOGUARD INC
SEAL BEACH, CA · 4 employees · woman-owned
“SBIR Phase II: Cryogenic probe development and testing for post-lumpectomy margin ablation treatment”
National Science Foundation · Phase Phase II
TRANS ASTRONAUTICA CORPORATION
PACOIMA, CA · 23 employees
“Trans Astronautica’s Sutter Turn Key Observatory”
Department of Defense · Phase Phase II
BioDynamik
lake forest, CA · 5 employees
“SBIR Phase I: Innovative actuating smart implant device of Transverse Tibial Transport technology for the treatment of Diabetic Foot Ulcers”
National Science Foundation · Phase Phase I
INNEOS LLC
PLEASANTON, CA · 30 employees
“High Power VCSEL Design for Ruggedized 50 Gbps Transmitter Optical Subassembly”
Department of Defense · Phase Phase I
ELVE INC
DAVIS, CA · 46 employees
“Millimeter-wave amplifiers for space communications”
Department of Defense · Phase Phase II
Roam Robotics, Inc
SAN FRANCISCO, CA · 13 employees
“Powered Knee Exoskeleton for Airfield Operations”
Department of Defense · Phase Phase II
HYPERKELP INC
ENCINITAS, CA · 6 employees
“HyperKelp Covert Ocean Monitoring Buoy System (COMBS)”
Department of Defense · Phase Phase II
GENESIS CODES INCORPORATED
Menlo Park, CA · 6 employees
“Feasibility Study of Genesis Codes’ Data Transport Solution On Tactical Radio to Improve Speed, Security and Resilience”
Department of Defense · Phase Phase I
INVERSION SPACE COMPANY
Los Angeles, CA · 61 employees
“Modular Payload Container for Earth Re-Entry”
Department of Defense · Phase Phase II
Om Therapeutics Inc.
SAN DIEGO, CA · 3 employees
“SBIR Phase I: Massive, empirical, scalable generation of small molecule and protein interaction data to enable the discovery of medicines at”
National Science Foundation · Phase Phase I
GEOOPTICS, INC.
PASADENA, CA · 5 employees
“Swarm Radar Surveyor for Space Based Environmental Monitoring”
Department of Defense · Phase Phase II
SWR TECHNOLOGY INC.
FREMONT, CA · 4 employees
“Combining Sound and Magnetic fields to transfer power through Seawater and Metals (CoSoMaSaM)”
Department of Defense · Phase Phase I
ACREE TECHNOLOGIES INCORPORATED
CONCORD, CA · 15 employees
“Anti-Corrosion Coating for Gas Turbine Compressor Components Operating in Marine Environments”
Department of Defense · Phase Phase I
ELECTROMAGNETIC SYSTEMS, INC.
EL SEGUNDO, CA · 23 employees
“All-Aspect Maritime Automatic Target Recognition”
Department of Defense · Phase Phase I
BRELYON INC.
REDWOOD CITY, CA · 33 employees
“Ultra Reality Extend: Enhanced Situational Awareness via Amplified Indirect Vision”
Department of Defense · Phase Phase I
GSI TECHNOLOGY, INC.
SUNNYVALE, CA · 168 employees
“AI Accelerator for Edge Computing”
Department of Defense · Phase Phase I
HYDROPLANE LTD
SHERMAN OAKS, CA · 15 employees · woman-owned
“Hydroplane Fuel Cell Powerplant for Mobile Energy Generation, Storage, and Electric Propulsion”
Department of Defense · Phase Phase I
STARNAV LLC
RIVERSIDE, CA · 6 employees
“Self-Contained Signal of Opportunity-Based PNT”
Department of Defense · Phase Phase II
ANSYNC INC.
EL DORADO HILLS, CA · 36 employees
“Modular Open Architecture for Small Form Factor Technology (MOAST)”
Department of Defense · Phase Phase I
ANTARA TEKNIK LLC
GRANITE BAY, CA · 17 employees
“Standardized, Modular and Scalable Wideband Multifunction Radio Frequency Payloads”
Department of Defense · Phase Phase I
K2 SPACE CORPORATION
TORRANCE, CA · 195 employees
“K2 Space Mega Class Satellite”
Department of Defense · Phase Phase II
WATER ILLUMINATION INC
Lake Forest, CA · 4 employees · woman-owned
“Demonstration of a Chemical-free Short-wavelength UV Based PFAS Destruction Technology for Saline Wastewater Treatment”
Environmental Protection Agency · Phase Phase II
E-SKIN DISPLAYS, INC.
PLEASANTON, CA · 1 employee
“Lightweight Longwave Bolometer Sensor Components”
Department of Defense · Phase Phase I
EDLORE INC.
LAGUNA HILLS, CA · 6 employees · woman-owned
“Edlore AI/ML Maintenance On-Prem Platform”
Department of Defense · Phase Phase II
ADVANCED LIFE TECHNOLOGIES, LLC
SANTA BARBARA, CA · 3 employees
“RoboMedic”
Department of Defense · Phase Phase I
Mavericks Photonics, Inc.
SAN FRANCISCO, CA · 1 employee
“PRISM: PRecise Interferometers as Stratospheric Microphones”
Department of Defense · Phase Phase I
TERASPATIAL INC
PALO ALTO, CA · 12 employees
“Ultra-Wideband, Low-Voltage, Low-power, Low Phase Noise CMOS Voltage Controlled Oscillator”
Department of Defense · Phase Phase II
AVANTGEN INC
SAN DIEGO, CA
“DEVELOPMENT OF RABBIT MONOCLONAL ANTIBODIES FOR FERRET BIOMARKERS.”
Department of Health and Human Services · Phase Phase II
GENCYTE THERAPEUTICS INC
SAN CARLOS, CA · 1 employee
“PHASE I SBIR CONCEPT AWARD FOR LOGIC GATED MOLECULAR ADAPTOR SYSTEM FOR JMML TREATMENT”
Department of Health and Human Services · Phase Phase I
TippingPoint Biosciences, Inc.
Los Altos, CA · 3 employees · woman-owned
“SBIR FY25 CONCEPT AWARD: TARGETING DYSFUNCTIONAL CHROMATIN NETWORKS IN DIPG”
Department of Health and Human Services · Phase Phase I
ADELPHI TECHNOLOGY INC
REDWOOD CITY, CA · 20 employees
“A COMPACT SOURCE FOR NEUTRON CAPTURE THERAPY FOR PONTINE GLIOMA.”
Department of Health and Human Services · Phase Phase I
ASO Therapeutics Inc.
San Rafael, CA · 2 employees
“FY2025 SBIR CONCEPT CLEARANCE AWARD OR TOPIC DEVELOPMENT OF THERAPEUTIC OR PREVENTATIVE TECHNOLOGIES FOR TREATMENT OR PREVENTION OF PEDIATRI”
Department of Health and Human Services · Phase Phase I
BIG EYE DIAGNOSTICS INC
SAN DIEGO, CA · 8 employees
“An Antigen-Based Rapid Test to detect L. loa infections, Aimed at Supporting Onchocerciasis Elimination Programs”
Department of Health and Human Services · Phase Phase I
QOOLABS INC
CARLSBAD, CA · 12 employees · woman-owned
“AFFINITY REAGENTS FOR THE IMMUNE SYSTEM OF GUINEA PIGS IL1B, IL2, IL4, IL6, IL8, IL10, IL12, AND IL13.”
Department of Health and Human Services · Phase Phase II
MARWELL BIO INC
SOUTH SAN FRANCISCO, CA · 2 employees · woman-owned
“NEXT GENERATION DUAL TARGETING ADCS FOR SCLC EMPOWERED BY GENERATIVE AI.”
Department of Health and Human Services · Phase Phase I
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