Recently funded science companies in North Carolina

Vulcan Elements Inc.

28 open roles on the board

Durham, NC · 8 employees · Department of Defense · Phase I/II · company site

“Establishing a Domestic, Rare-Earth Metal Manufacturing Supply Chain to Support Critical Department of Air Force Needs”

Corvid ATEA, LLC

Mooresville, NC · 16 employees · Department of Defense · Phase I/II

“Innovations in Heater Technologies for Optimized Heating during Welding”

United Protective Technologies, LLC

Locust, NC · 93 employees · Department of Defense · Phase I/II · company site

“Solid High-performance Innovative Engine Lubrication for Durability (SHIELD)”

Ingenia Services Inc

Wake Forest, NC · 13 employees · Department of Defense · Phase I · company site

“Social-Cyber Modeling and Simulation”

Axnano LLC

Greensboro, NC · 7 employees · Department of Defense, Environmental Protection Agency · Phase I/II · company site

“Sustainable, Non-Incineration-based Destruction of Air Force Hazardous Waste Stockpiles : TACFI”

Ncx Corporation

Raleigh, NC · 8 employees · Department of Defense · Phase I/II · company site

“VANTAGE: Versatile Array Nanotube Tomography for Advanced Ground Exploitation”

Jms Southeast Inc.

Statesville, NC · 83 employees · Department of Defense · Phase I · company site

“Testing Requirements to Complete R&D for Source Approval, NSN 4710015077949”

Gateway Bio, Inc.

Durham, NC · 5 employees · Department of Health and Human Services · Phase I

“Next Generation Stealth Lipid for the Delivery of mRNA”

Careyaya Health Technologies Inc

Raleigh, NC · 5 employees · Department of Health and Human Services · Phase I · company site

“YayaGuide: AI-Enabled Personalized Training for Caregivers of Older Adults with ADRD”

Persistence Therapeutics, Inc.

Chapel Hill, NC · 1 employee · Department of Health and Human Services · Phase I

“The SynthNode Paradigm: Reimagining CAR T Cell Therapy for Improved Patient Outcomes”

Artiam Bio Inc.

Cary, NC · 2 employees · Department of Health and Human Services · Phase I · company site

“Validation of APT101 for the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) in an Aging Murine Model”

Synvest Imaging Inc.

Chapel Hill, NC · 0 employees · Department of Health and Human Services · Phase I

“Scalable cGMP production of SV2A PET tracers using photoredox chemistry for applications in clinical trials and early AD diagnosis”

Epicypher, Inc.

Durham, NC · 55 employees · Department of Health and Human Services · Phase II · company site

“Development of novel epigenetic biomarkers and detection reagents for aging”

Callahan-Young LLC

Raleigh, NC · 2 employees · Department of Health and Human Services · Phase II · woman-owned · company site

“Evaluating the Health Benefits of Jigsawdio: A Novel Multisensory Jigsaw Puzzle-based Intervention for Alzheimer's Disease and Related Demen”

Bedrock Therapeutics, Inc.

Raleigh, NC · 4 employees · Department of Health and Human Services · Phase I

“Intramuscular Administration of AAV Vectors Encoding soluble PD-L1 for Rheumatoid Arthritis Treatment”

Intra Therapeutics, LLC

Cary, NC · 2 employees · Department of Health and Human Services · Phase I

“Development of Localized Triple-Negative Breast Cancer Immunotherapy”

Perfusio Corp.

Greenville, NC · 8 employees · Department of Health and Human Services · Phase I · company site

“Project MATCH: Multi-spectral AI/ML powered Burn and Wound Evaluation Technology using a Cost-Effective Handheld Device.”

Biomojo LLC

Cary, NC · 8 employees · Department of Defense · Phase II · woman-owned · company site

“nXcomms: Intelligent Patient Simulation”

Mucommune, LLC

Carrboro, NC · 4 employees · Department of Health and Human Services · Phase I/II

“SBIR: In vivo engineering of multifaceted B7H3.CAR-T cells for cellular immunotherapy of pancreatic ductal adenocarcinoma”

Neurogt Inc

Durham, NC · 2 employees · Department of Health and Human Services · Phase I/II · woman-owned

“Trans-BBB AAV9 gene therapy targeting CNS neuropathy of MPS I”

Corvid Technologies, LLC

Mooresville, NC · 416 employees · Department of Defense, Department of Energy, National Aeronautics and Space Administration · Phase I/II · company site

“Surrogate Model for High-Fidelity Physics-Based Post Intercept Debris Generation”

Foresightcares Inc.

Matthews, NC · 2 employees · National Science Foundation · Phase II · woman-owned · company site

“SBIR Phase II: AI-based Accessible Visual-Assessment App for Active Healthy Aging of Older Adults”

Atsena Therapeutics, Inc.

Durham, NC · 16 employees · Department of Health and Human Services · Phase II · company site

“Manufacturing Development and Commercial Readiness of an Adeno-Associated Virus-Based Gene Therapy for the Treatment of Leber Congenital Ama”

Freescale LLC

Cary, NC · 3 employees · National Science Foundation · Phase II · woman-owned · company site

“SBIR Phase II: Development and Analysis of Functional NanoInks for Printed Neuromorphic Electronics and Smart Sensors”

Cypress BioPharma

Cary, NC · 10 employees · Department of Health and Human Services · Phase I

“Leveraging the Highly Active Metabolite of Pioglitazone as a Scaffold for a Novel Non-Immunosuppressive Therapy for Childhood Nephrotic Synd”

Eldec Pharmaceuticals Inc.

Chapel Hill, NC · 3 employees · Department of Health and Human Services · Phase I

“Novel peptide therapeutics to treat cystic fibrosis-related diabetes”

Oxford Defense North Carolina LLC

Youngsville, NC · 2 employees · National Aeronautics and Space Administration · Phase I · company site

“Scalable Beamed Energy Laser Concentrator”

Baebies, Inc.

Durham, NC · 50 employees · Department of Defense, Department of Health and Human Services · Phase I/II · company site

“A Rapid, Point-of-Care Diagnostic to Identify Viable Sexually Transmitted Infections, Reduce Overtreatment, and Prevent Emerging Antibiotic ”

Luxbiome Inc

Cary, NC · 2 employees · Department of Health and Human Services · Phase I

“Arsenic Removal from the Body Through Mechanism-Guided Gut Microbiome Modulation”

Vast Therapeutics

Morrisville, NC · 7 employees · Department of Health and Human Services · Phase II · company site

“Nebulized ALX1 as a Treatment for Difficult Non-tuberculous Mycobacterial Lung Infections”

Innovation Research And Training, Inc.

Durham, NC · 26 employees · Department of Health and Human Services · Phase II · woman-owned · company site

“Fundamental Training for Formal and Informal STEM Mentors”

Data Driven Bioscience Inc

Durham, NC · 4 employees · Department of Health and Human Services · Phase I/II

“Validation of Duoseq as a Genomic Swiss Army Knife for the Diagnosis of Lymphomas”

Gradient Medical, Inc.

Cary, NC · 1 employee · Department of Health and Human Services · Phase II · company site

“Commercialization of Algorithmic Non-thermal Ablation Technology for the Treatment of Inoperable Tumors”

Ramona Optics Inc

Durham, NC · 30 employees · Department of Health and Human Services · Phase I · company site

“Rapid inter-procedural 3D scanning of fine-needle aspiration cytology slides with a parallelized microscope”

Glyco Discoveries, Inc

Raleigh, NC · 10 employees · Department of Health and Human Services · Phase II

“Development of synthetic heparin to protect liver graft from ischemia reperfusion injury during transplantation”

Carolina Instruments LLC.

Chapel Hill, NC · 4 employees · Department of Health and Human Services · Phase I · company site

“A novel system for tracking arousal-related dynamics in freely moving animals”

Reselute, Inc.

Durham, NC · 5 employees · Department of Health and Human Services · Phase I · woman-owned · company site

“Local and Sustained Release of Antibiotics in the Surgical Treatment of Diabetic Charcot Foot”

Clearsens, Inc.

Raleigh, NC · 3 employees · National Aeronautics and Space Administration · Phase I · company site

“Compact Wearable Ultrasonic Monitoring System for In-Suit Venous Gas Emboli Detection”

Deep Creek Pharma, LLC

Winston-Salem, NC · 4 employees · Department of Health and Human Services · Phase I · company site

“Modified Thrombin Binding Aptamer Treatment of CRC Metastasis”

Oraliva, Inc.

Durham, NC · 1 employee · Department of Health and Human Services, National Science Foundation · Phase I/II

“Point of care diagnostic to improve access to gynecological screening in low-resource settings”

Inhalon Biopharma, Inc.

Morrisville, NC · 0 employees · Department of Health and Human Services · Phase II

“Development of IN-003PI as passive immunization against human metapneumovirus infection”

Sidetrack Ventures, LLC

Durham, NC · 1 employee · Department of Health and Human Services · Phase I · woman-owned

“Development of an innovative tool to improve mTBI patient-provider communication of visual impairment symptoms”

Round Table Research, Inc.

Hillsborough, NC · 2 employees · Department of Health and Human Services · Phase I

“Advancing Extracellular Vesicle Therapy for Brain Cancer”

Vortant Technologies LLC

Weaverville, NC · 3 employees · Department of Health and Human Services · Phase I · company site

“Spatially transparent binaural beamforming for noise reduction in cochlear implant processors”

Vigilant Cyber Systems, Inc.

Mount Airy, NC · 22 employees · Department of Defense · Phase II · company site

“Automatic Virtual Target Generator”

Cymantix, Inc.

Pittsboro, NC · 9 employees · Department of Defense · Phase I · company site

“DiscoverOS: Transforming Cyber Threat Intelligence with GenAI”

Secmation LLC

Cary, NC · 12 employees · Department of Defense · Phase I/II · company site

“Interoperability and Usability Enhancements for the Anneal Embedded Hypervisor”

Pryon Incorporated

Raleigh, NC · 100 employees · Department of Defense · Phase I/II · company site

“Pryon RAG Suite : Building Blocks for DoD AI Applications”

Antixero

Raleigh, NC · 0 employees · Department of Health and Human Services · Phase I

“AntiXero: An extended duration solution for cancer-associated dry mouth.”

eXclaim IP, LLC

Cornelius, NC · 6 employees · Department of Defense · Phase I/II · company site

“Operational Dominance Through Resilient UAS: Passive Thermal and EMP Protection for Mission-Critical Drone Systems”

Cybermedics LLC

N Topsail Beach, NC · 2 employees · Department of Defense · Phase I

“Virtual Medical Twin and Adaptive Medical View Technologies for Predictive Simulation of Injury Progression”

Phaxtec, Inc.

Wake Forest, NC · 1 employee · National Science Foundation · Phase II

“SBIR Phase II: Production of Biopolymer Coatings for Paper Used in Foodservice Packaging”

Nabgen Inc

Durham, NC · 3 employees · Department of Health and Human Services · Phase II · company site

“Novel strategy to block AAV neutralizing antibody activity”

Parion Sciences, Inc.

Durham, NC · 19 employees · Department of Health and Human Services · Phase II

“A Novel ENaC Blocker/Osmolyte Inhalation Solution for the Treatment of Muco-Obstructive Lung Diseases”

Adroit Materials, Inc.

Apex, NC · 8 employees · Department of Defense · Phase I/II · company site

“Solar blind UVC detectors for efficient plume detection”

Vulcan Ventura LLC

Concord, NC · 2 employees · Department of Defense · Phase II

“AF241-0004: Context-Aware RF Electromagnetic Surveying for Exploiting Signals of Opportunity”

Swift Universal Optical Systems LLC

Spring Lake, NC · 15 employees · Department of Defense · Phase I/II

“Thermal Barrier Minimal Deflection Handguard”

Attagene, Inc.

Morrisville, NC · Department of Health and Human Services · Phase II

“A Two-Tier Effect-Based Water Bioactivity Surveillance System.”

Vadum Inc

Raleigh, NC · 45 employees · Department of Defense · Phase II · company site

“Context Aware Machine Learning Signal System”

Regennova, Inc.

Durham, NC · 3 employees · Department of Health and Human Services · Phase II

“Arginine-Polyamine Pathway Inhibitor for Treatment of ADPKD”

American Droid, LLC

New Bern, NC · 4 employees · Department of Defense · Phase I/II · company site

“Robotic End-Effector Direct Drive Motor Design”

Atmospheric Plasma Solutions, Inc.

Cary, NC · 20 employees · Department of Defense · Phase I · company site

“Integrated Cobot and Atmospheric Plasma Surface Preparation System to Enhance Operational Activities”

Drive Therapeutics, L.L.C.

Chapel Hill, NC · 3 employees · National Science Foundation · Phase II · company site

“SBIR Phase II: Optimizing Manufacturing Efficiency of Bispecific Aptamer Therapeutics”

Polaronyx Inc

Chapel Hill, NC · 10 employees · National Aeronautics and Space Administration · Phase II · company site

“Biomimetic Zero CTE Lightweight Optical Structures”

SimplusDx, Inc.

Durham, NC · 4 employees · Department of Health and Human Services · Phase I · company site

“A rapid point-of-care test for therapeutic drug monitoring of tacrolimus”

Cerulean Scientific Inc

Durham, NC · 7 employees · Department of Health and Human Services · Phase II · company site

“Slippery, Omniphobic Coating to Prevent Thrombosis and Biofilm Formation on Peripheral Vascular Grafts”

Calla Health Foundation

Durham, NC · 3 employees · Department of Health and Human Services · Phase I · woman-owned

“Development and validation of patient-ready Callascope for cervical imaging”

Piximune, Inc.

Durham, NC · 3 employees · Department of Health and Human Services · Phase I

“Antibody-based gene-agnostic treatment for inherited retinal degeneration”

Soelect Inc

Greensboro, NC · 22 employees · Department of Defense · Phase II · company site

“Rapid and Facile Manufacturing of All Dry Electrode Solid State Batteries for High Temperature and Voltage Applications”

Altis Biosystems, Inc.

Durham, NC · 23 employees · Department of Health and Human Services · Phase II · company site

“Mucus and ALI Models of the Human Intestine”

Aura Technologies, LLC

Durham, NC · 31 employees · Department of Defense · Phase I · company site

“MVDC Fault DLI Relay”

Oncotab, Inc.

Waxhaw, NC · 1 employee · Department of Health and Human Services · Phase I · company site

“Optimized targeted radiotherapy of pancreatic cancer”

Innovaknits, LLC

Conover, NC · 5 employees · Department of Defense · Phase II · company site

“Continued design, development, optimization, and testing of seamless garments created using State-of-the-Art Stoll and Shima Seiki knitting ”

Third Floor Materials, Inc.

Durham, NC · 3 employees · Department of Defense · Phase I

“Compressive hyperspectral imaging with free-form plasmonic filter arrays”

Junipero Therapeutics, Inc.

Durham, NC · 1 employee · National Science Foundation · Phase I · company site

“SBIR Phase I: Epigenome Editing by Induced Proximity Using Oligonulcleotide-conjugates”

ScitoVation, LLC

Research Triangle Park, NC · 13 employees · Department of Health and Human Services · Phase II · company site

“Triage of Developmental and Reproductive Toxicants using an In vitro to In Vivo Extrapolation (IVIVE)-Toxicokinetic Computational modeling A”

Teleswivel LLC

Durham, NC · 1 employee · Department of Defense · Phase II · company site

“Replacing the Pintle/Lunette: Autonomous Vehicle Towing”

Mimetics, LLC

Chapel Hill, NC · 3 employees · Department of Energy · Phase II · company site

“Applying Dynamical Systems Theory to Improve Analysis of Time Series Transcriptional Data from Bioproduction Processes”

OpiAID, LLC

Wilmington, NC · 2 employees · Department of Health and Human Services · Phase II · company site

“Development of the OpiAID strength band platform”

Social Cascade, Inc.

Cary, NC · 2 employees · Department of Health and Human Services · Phase I · company site

“Integrating AI nowcasting models with digital communications to reduce RSV infections in rural areas”

Aegis Power Systems Inc

Murphy, NC · 25 employees · Department of Defense · Phase I · woman-owned · company site

“Wide Bandgap High Power High Density Inverter Ruggedization and Characterization Study”

3-C Institute For Social Development Inc

Chapel Hill, NC · 25 employees · Department of Health and Human Services · Phase II · woman-owned · company site

“A Mobile Text Approach to Measurement and Feedback for Wraparound Care Coordination”

Lupine Materials and Technology, Inc.

Mebane, NC · 4 employees · Department of Energy · Phase I · company site

“Development of Low Microbend Loss Radiation Resistant Fiber”

Resonantia Diagnostics, Inc.

Durham, NC · 1 employee · National Science Foundation · Phase I

“SBIR Phase I: Acoustic Sensor Based Point of Care Diagnostic Platform for Rapid Identification and Antimicrobial Susceptibility Testing”

Geometric Data Analytics Inc.

Durham, NC · 11 employees · Department of Defense · Phase II · company site

“AIDA: Artificial Intelligence Design Assistant”

VQBiomedical

Apex, NC · 6 employees · Department of Defense · Phase II · company site

“Development of a Portable Automated System for Intravascular Delivery of Oxygen”

Raglan LLC

Wilmington, NC · 22 employees · Department of Defense · Phase II · company site

“Family of Special Operations Vehicles Open Topic”

Smart Material Solutions LLC

Raleigh, NC · 4 employees · Department of Defense · Phase I · company site

“Light-trapping features made with a scalable nanomanufacturing process”

ForagR Medicines Inc

Durham, NC · 3 employees · National Science Foundation · Phase I

“SBIR Phase I: High-throughput platform for small molecule, in-cell targeting of undruggable proteins via their mRNAs”

Lumeova Inc

Raleigh, NC · 5 employees · Department of Defense · Phase I · company site

“Ultra-Wideband High-Power Digital Fiber Optic Transmitter Laser”

mHealth Systems, Inc

Waxhaw, NC · 1 employee · Department of Health and Human Services · Phase I

“MiREA, a mHealth intervention to Reduce Health Disparities by Improving Equitable Access to Mandated College Students with Problematic Alcoh”

Greenlifetech Corp

Banner Elk, NC · 5 employees · Environmental Protection Agency · Phase II · company site

“Novel Method for Produce Preservation and Sterilization in Modern Refrigerators”

Collaborations Pharmaceuticals Inc

Fuquay Varina, NC · 16 employees · Department of Health and Human Services · Phase II · company site

“Pyronaridine as an oral Treatment for Ebola”

Radiant Dx Inc.

Durham, NC · 1 employee · Department of Health and Human Services · Phase I

“CLARITAS: PHENOTYPIC AND MULTI-OMIC READOUTS TO INFORM RARE CANCER COMBINATION THERAPY”

EydisBio, Inc.

Durham, NC · 3 employees · Department of Health and Human Services · Phase I

“Development of selective NS5 inhibitors for the broad-spectrum treatment of flaviviruses”