Recently funded science companies in Illinois
76 companies in Illinois closed federal SBIR/STTR awards in the last two years, newest first. The funding event is the signal — small companies grow right after the award lands.
MEMQ INC
CHICAGO, IL · 6 employees
“Cryo-Compatible Electro-Optic Modulation Using Scalable Commercial TFLN Foundry Platform”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I
DIGITAL OPTICS TECHNOLOGIES INC
ROLLING MEADOWS, IL · 6 employees
“Lithium Niobate In-Phase/Quadrature Modulator for High-Bandwidth Data Transmission at Cryogenic Temperatures”
Department of Defense · Phase Phase I/Phase II
EPIR, INC.
BOLINGBROOK, IL · 30 employees
“FEM GeniusóAI-powered Intelligent Agent for Automated Finite-Element Modeling of Aerospace Structures”
Department of Defense · Phase Phase I/Phase II
HIDENN-AI, Inc.
Evanston, IL · 6 employees
“AI-based software toolkit for finite element modeling of aerospace structures based on Convolutional Hierarchical Deep-l Learning Neural Net”
Department of Defense · Phase Phase I/Phase II
Sunstream Scientific Incorporated
Chicago, IL · 1 employee
“Servo Throttle Strategy for Solid Fuel Ramjet”
Department of Defense · Phase Phase I
RESDEF INC. (DBA Frontier Audio Labs)
CHICAGO, IL · 7 employees
“Machine Learning and Array Beamforming Military Boom Microphone”
Department of Defense · Phase Phase I/Phase II
Integrated Dynamics, Inc.
CHICAGO, IL · 3 employees
“SBIR Phase I: High-Temperature Fermentation for Volatile Organic Chemical Production”
National Science Foundation · Phase Phase I
N'WAII INC.
NAPERVILLE, IL · 1 employee
“First in Class Mitochondrially targeted antioxidants with transcriptional modulator capabilities and their implication in the diseases of th”
Department of Health and Human Services · Phase Phase I
STARFIRE INDUSTRIES, LLC
CHAMPAIGN, IL · 44 employees
“PVD manufacturing process for inner protective liners enabling advanced cladding compositions to reduce fuel-cladding chemical interactions,”
Department of Energy · Phase Phase I
Neurolux, Inc.
NORTHFIELD, IL · 7 employees
“Development and Validation of a Compliant Reversible Actuator and Detector Leveraging Electrophysiology for Organoids (Organoid-CRADLE)”
Department of Health and Human Services · Phase Phase I
QDIR, INC.
CHICAGO, IL · 3 employees
“A Systematic Approach to High Operating Temperature (HOT) Colloidal Quantum Dot Infrared Photodetectors”
Department of Defense · Phase Phase I/Phase II
ZINNIA TECHNOLOGIES INC.
WINNETKA, IL · 4 employees
“Zinnia All Day: An application for mobile devices and connected TVs to assist care partners promote routine in activities of daily living in”
Department of Health and Human Services · Phase Phase I
O2M TECHNOLOGIES LLC
CHICAGO, IL · 9 employees
“Advanced Imaging Methods in Pulse EPR”
Department of Health and Human Services · Phase Phase II
ZECOAT CORPORATION
GRANITE CITY, IL · 9 employees
“Micrometeorite Shield with Tailorable, High-Performance, Thermal/Optical Properties for Spacecraft Telescope Baffle”
National Aeronautics and Space Administration · Phase Phase I
HINETICS LLC
CHAMPAIGN, IL · 20 employees
“Health monitoring and pre-flight diagnostics for robust electrical machines”
National Aeronautics and Space Administration · Phase Phase I
Third Coast Dynamics, Inc.
EVANSTON, IL · 1 employee
“Anatomic Imaging Derived 4D Hemodynamics using Deep Learning”
Department of Health and Human Services · Phase Phase II
HOMECARE HUB US INC
WILLOW SPRINGS, IL · 12 employees
“Scaling a network of small community-based care homes as a high-value alternative to institutional care”
Department of Health and Human Services · Phase Phase II
MICROLINK DEVICES INC
NILES, IL · 60 employees
“Radiation Resistant Solar and Laser Power Converter for Lunar Applications”
National Aeronautics and Space Administration · Phase Phase I
BRIGHTOUTCOME INC
BUFFALO GROVE, IL · 7 employees
“WHIM (Women's Health in Menopause): Promoting healthy aging in menopausal women”
Department of Health and Human Services · Phase Phase I
ANGIOTENSIN THERAPEUTICS, INC.
Evanston, IL · 3 employees
“AGT001 for Delayed Graft Function in Kidney Transplantation”
Department of Health and Human Services · Phase Phase I
Laborecom Therapeutics Inc
Chicago, IL · 3 employees
“A cell-permeable peptide therapeutic to reduce myocardial reperfusion injury”
Department of Health and Human Services · Phase Phase I
COMMON GROUND PUBLISHING, LLC
CHAMPAIGN, IL · 17 employees
“CGScholar AI Helper: A Generative AI Writing and Learning Assistant”
Department of Education · Phase Phase II
VORTEX THERAPEUTICS INC
LOMBARD, IL · 2 employees
“Development of a novel MYC inhibitor for cancer therapy”
Department of Health and Human Services · Phase Phase II
QuesTek Innovations LLC
Evanston, IL · 42 employees
“Multi-scale location-specific fatigue life prediction for additive propulsion components”
Department of Defense · National Aeronautics and Space Administration · Phase Phase I
Regenerative Medical Solutions Inc
Park Ridge, IL · 7 employees
“Development of a safer stem cell-based diabetes therapy via suicide gene-mediated ablation of proliferative cells”
Department of Health and Human Services · Phase Phase II
INFLUIT ENERGY LLC
CHICAGO, IL · 30 employees
“American-Made High-Energy Density Flow Battery with Neutral pH Electrolytes for Tactical and Strategic Energy Resilience”
Department of Defense · Phase Phase II
MAIA Biotechnology, Inc.
Chicago, IL · 12 employees
“Novel Telomere-Targeting Therapy for Advanced Non-Small Cell Lung Cancer”
Department of Health and Human Services · Phase Phase II
EVOQUANT LLC
Chicago, IL · 1 employee
“Leveraging Large Scale Bioinformatics and AI for Natural Product Drug Discovery and Target Selection”
Department of Health and Human Services · Phase Phase I
APPLIED MATERIAL SYSTEMS ENGINEERING, INC
STREAMWOOD, IL · 7 employees
“Innovative Advances in Coatings for Extreme Environmental Thermal Radiators and Complex Surfaces”
National Aeronautics and Space Administration · Phase Phase I
PeptiForge, Inc
Chicago, IL · 3 employees
“A platform for the rapid development of protein binders”
Department of Health and Human Services · Phase Phase I
DOCBOTIC INC
NAPERVILLE, IL · 5 employees · woman-owned
“Betterbot: Promoting Accessible and Inclusive Mental Health Support for Individuals with Brain Injury”
Department of Health and Human Services · Phase Phase I
UPTAKE TECHNOLOGIES, INC.
Chicago, IL · 21 employees
“Next Generation Condition-Based Maintenance Plus for USAF”
Department of Defense · Phase Phase I/Phase II
VILLA-TECH, INC.
NAPERVILLE, IL · 14 employees
“"Revolutionizing Infrastructure/security and compliance for the warfighter using AI/NLP"”
Department of Defense · Phase Phase I
FALEX CORPORATION
SUGAR GROVE, IL · 36 employees
“Next-Gen Fuel Testing: Automating Breakpoint Detection with an Upgraded Thermal Oxidation Stability Test Equipment”
Department of Defense · Phase Phase II
LIFEBOAT LLC
CHAMPAIGN, IL · 9 employees
“NetCDF4 / HDF5 Format Extension Pack (NFEP): Transparently Adding More Formats to NetCDF4 and HDF5”
Department of Energy · National Aeronautics and Space Administration · Phase Phase I/Phase II
IRIS LIGHT TECHNOLOGIES INC
CHICAGO, IL · 4 employees
“Low SWAP frequency combs for RF photonic chips and portable atomic clocks enabled by black phosphorus actives”
Department of Defense · Department of Energy · Phase Phase I/Phase II
IMPOSSIBLE OBJECTS, INC.
NORTHBROOK, IL · 24 employees
“High-Volume Low-Cost Long-range Fixed Wing UAS with near-conflict Distributed Manufacturability”
Department of Defense · Phase Phase I/Phase II
RATIONAL CYPHY INC
CHAMPAIGN, IL · 3 employees
“SkyAID: A Safe Autonomy Infrastructure for Disaster Response”
National Aeronautics and Space Administration · Phase Phase II
SIVANANTHAN LABORATORIES, INC.
BOLINGBROOK, IL · 30 employees
“Metasurface-coupled HgCdTe alloys for nonreciprocal optical limiting”
Department of Defense · Phase Phase I/Phase II
Midgard AI, INC.
Chicago, IL · 3 employees
“Highly Photorealistic Programmable 3D Worlds”
National Aeronautics and Space Administration · Phase Phase II
DUPAGE MEDICAL TECHNOLOGY, INC.
Willowbrook, IL · 2 employees
“A new drug to treat transplant-associated renal ischemia-reperfusion injury”
Department of Health and Human Services · Phase Phase I
BRITESEED, LLC
CHICAGO, IL · 7 employees
“Development of a Multispectral Kerrison Rongeur for Dura and Nerve Root Detection”
Department of Health and Human Services · Phase Phase II
SNC THERAPEUTICS, INC.
EVANSTON, IL · 2 employees
“Tolerogenic Nanotherapy to Delay Type I Diabetes”
Department of Health and Human Services · Phase Phase I
FLUID REALITY INCORPORATED
CHICAGO, IL · 2 employees
“SBIR Phase I: Compact Haptic Actuators Using Electroosmotic Pumps”
National Science Foundation · Phase Phase I
AI TECH HOLDINGS INC
Chicago, IL · 9 employees
“Integration of Physiological Alerting and Location Monitoring from WearTAK-Mil into Special Tactics Radio Data Transport Layers”
Department of Defense · Phase Phase II
Mantis Tech, LLC
Oswego, IL · 100 employees
“Marksmanship Analysis and Training Information System (MANTIS)”
Department of Defense · Phase Phase I
CREATIVE THERMAL SOLUTIONS, INC.
URBANA, IL · 26 employees
“Development of a Shipboard Modular Refrigeration System Using Carbon Dioxide as the Refrigerant”
Department of Defense · Phase Phase I/Phase II
Tango Biosciences Inc.
Chicago, IL · 3 employees
“The Avidimer Platform - a molecular toolbox to accelerate proximity research and drug discovery”
Department of Health and Human Services · Phase Phase I
EARNEST AGRICULTURE, INC.
RANTOUL, IL · 2 employees
“STTR Phase I: Development of Seed Applied Bacterial Consortium for Soybean to Increase Yield, Nitrogen Fixation, Disease Resistance, and Aft”
National Science Foundation · Phase Phase I
NUTS TECHNOLOGIES INC
GLENCOE, IL · 4 employees
“TALON2D: Tactical Autonomous Layer for Optimized Networking with Distributed and Decentralized Key Management”
Department of Defense · Phase Phase I
INGENIUM TECHNOLOGIES CORP
ROCKFORD, IL · 36 employees
“Advanced Ceramic Electrochemical Cell for Oxygen Production”
Department of Defense · Phase Phase II
ENDUVO INC
PEORIA, IL · 19 employees
“Enduvo TACFI - RAISE: Rapid AI-Immersive Scalable Education”
Department of Defense · Phase Phase II
NUAGO THERAPEUTICS INC
CHICAGO, IL · 1 employee
“Development of a DISE-inducing, short RNA therapeutic to treat ovarian cancer”
Department of Health and Human Services · Phase Phase I
OPERA BIOSCIENCE, INC.
EVANSTON, IL · 3 employees · woman-owned
“SBIR Phase II: A Gram-Negative Bacterial Secretion Platform for Cost-Effective, High-Purity Recombinant Protein Production”
National Science Foundation · Phase Phase II
Inertial Technologies Inc.
Chicago, IL · 1 employee
“STTR Phase I: Supersonic Inertial Separation for Carbon Capture Technologies”
National Science Foundation · Phase Phase I
A Cubed Design LLC
Aurora, IL · 3 employees
“SBIR Phase I: Novel Mechanism for Refreshable Braille Device with Embedded Curriculum”
National Science Foundation · Phase Phase I
CELADYNE TECHNOLOGIES, INC.
WILLOWBROOK, IL · 12 employees
“SPECTRE - Silent Propulsion, Extended Range, Covert Transport and Resupply Engine”
Department of Defense · Phase Phase II
SYNAPTICURE INC
KENILWORTH, IL · 1 employee
“3D in vitro model of genetic and sporadic FTD: accelerating novel therapeutic development”
Department of Health and Human Services · Phase Phase II
AMERICAN ENERGY TECHNOLOGIES CO
GLENVIEW, IL · 19 employees · woman-owned
“New and Improved Domestic Carbon Monofluoride for D-size lithium-primary battery cells.”
Department of Defense · Phase Phase II
Kompass Diagnostics Inc
Chicago, IL · 2 employees
“SBIR Phase I: Portable Blood Diagnostic Technology Enabling Care Delivery Beyond Hospital Walls”
National Science Foundation · Phase Phase I
HAAS, INC
CHICAGO, IL · 48 employees
“Child Safety Using Optical and V2X Digital Alerting Technology to Bring School Buses and Students on the Vehicle Grid for Collision Preventi”
Department of Transportation · Phase Phase II
Covira Surgical
North Chicago, IL · 3 employees
“A novel, non-antibiotic, microbiome-directed agent to prevent post-surgical infection”
Department of Health and Human Services · Phase Phase II
SENSEWHY, INC.
CHICAGO, IL · 4 employees
“ASHES: Assessing Smoking BeHavior with ThErmal Sensing to Prevent Relapse”
Department of Health and Human Services · Phase Phase I
SCIAKY INC
CHICAGO, IL · 54 employees
“Real-Time Adaptive Control for Conduction Mode EB Welding of Niobium Cavities”
Department of Energy · Phase Phase II
CAPORUS TECHNOLOGIES INC
ORLAND PARK, IL · 6 employees
“Engineered Substrates for Radiation-Hard Sensors in High Energy Physics”
Department of Energy · Phase Phase II
TERA-PRINT LLC
SKOKIE, IL · 7 employees
“Towards Rapid and Accessible DNA Synthesis for Synthetic Biology via Beam Pen Lithography”
Department of Energy · Phase Phase II
RHAEOS, INC
EVANSTON, IL · 5 employees
“Lowering Economic, Infrastructure, & Physical Barriers with Noninvasive, Wireless Telemedicine Cerebrospinal Fluid Flow Sensing for Pediatri”
Department of Health and Human Services · Phase Phase I/Phase II
BIOMESENSE INC
CHICAGO, IL · 7 employees
“Development of a Novel Biosensor to Accelerate Investigations of the Gut Microbiome”
Department of Health and Human Services · Phase Phase II
EDEN PARK ILLUMINATION, INC.
CHAMPAIGN, IL · 25 employees
“Development of a Portable Microplasma Far-UVC Source for the Prevention of Surgical Site Infections”
Department of Energy · Phase Phase I
ARTICULATE LABS, INC
Chicago, IL · 3 employees
“Accelerated Physical Rehabilitation & Improved Military Readiness Through Movement-Synchronous Electrical Muscle Stimulation”
Department of Defense · Phase Phase I
Kaney Aerospace, Inc.
Rockford, IL · 150 employees
“Final Development & Qualification of NSN 5996-01-419-3249 Aircraft Synchronous Amplifier”
Department of Defense · Phase Phase II
BELAY DIAGNOSTICS, LLC
CHICAGO, IL · 2 employees
“Multi-omic CSF Assay for the Diagnosis of Brain Cancers”
Department of Health and Human Services · Phase Phase II
NOVAA LTD
CHICAGO, IL · 4 employees
“Pressure-Tolerant Electronically Steered Antenna for Satellite Communications on Unmanned Undersea Vehicles”
Department of Defense · Phase Phase II
AZUL 3D INC
SKOKIE, IL · 20 employees
“Protective Eyewear with Vision Correction Using Continuous 3D Printing”
Department of Defense · Phase Phase I
HY-TEK MANUFACTURING CO., INC.
SUGAR GROVE, IL · 38 employees · woman-owned
“Steel Laminated Armor Plate (SLAP)”
Department of Defense · Phase Phase I
EPICWIDE, LLC
Chicago, IL · 1 employee
“Home-Use Synergy-Alleviating System.”
Department of Health and Human Services · Phase Phase I
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