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Recently funded science companies in South Carolina

19 companies in South Carolina closed federal SBIR/STTR awards in the last two years, newest first. The funding event is the signal — small companies grow right after the award lands.

INTEGER TECHNOLOGIES LLC

COLUMBIA, SC · 25 employees

Developing a Holistic Automated Fiber Placement Digital Engineering Solution (HADES)

Department of Defense · Phase Phase I

$140kawardedfunded 2025-11-03Company site →

ADVANCED SMART SYSTEMS AND EVALUATION TECHNOLOGIES, LLC

COLUMBIA, SC · 1 employee

Mitigating Injurious Falls in Older Adults Through Non-Injurious Fall and Gait Analysis From Floor Vibrations

Department of Health and Human Services · Phase Phase II

$1.2Mawardedfunded 2025-09-22

Sojourn MedTech LLC

Pendleton, SC · 3 employees

Patient-Centered Self-Cannulation Training Simulator to Promote Self-Care and Home Hemodialysis among African American Patients with Kidney

Department of Health and Human Services · Phase Phase I

$350kawardedfunded 2025-09-17

INSECTAPEL LLC

WELLFORD, SC · 6 employees

SBIR Phase II: Safe Long-Lasting Bio-Based Insect-Repellent Textiles

National Science Foundation · Phase Phase II

$1.1Mawardedfunded 2025-09-15

Zylo Therapeutics Inc.

GREENVILLE, SC · 5 employees

Development and optimization of a nitric oxide releasing microparticle formulation for the topical treatment of chronic rhinosinusitis

Department of Health and Human Services · Phase Phase I

$300kawardedfunded 2025-09-12Company site →

ALTRON, INC.

MOUNT PLEASANT, SC · 111 employees

UnifyRT: A Unified Solution for ASW Multi-Platform Capabilities

Department of Defense · Phase Phase I/Phase II

$3.2Macross 3 awardsfunded 2025-09-12Company site →

TETRAMER TECHNOLOGIES LLC

PENDLETON, SC · 25 employees · woman-owned

Engineered Beads for Chem-Bio Defense (CBD) Personal Protective Equipment (PPE)

Department of Defense · Environmental Protection Agency · Phase Phase I/Phase II

$1.5Macross 2 awardsfunded 2025-09-11Company site →

BLOTTING INNOVATIONS, INC

Central, SC · 3 employees

High-Throughput Western Blotting

Department of Health and Human Services · Phase Phase II

$1.1Mawardedfunded 2025-09-01

Integrated Micro-Chromatography Systems, Inc.

Irmo, SC · 35 employees

Chemoenzymatic methods and reagents to access affordable (iso)globo- and(neo)lacto-glycosphingolipids

Department of Health and Human Services · Phase Phase I

$315kawardedfunded 2025-09-01Company site →

VBASE Oil Company

PENDLETON, SC · 24 employees

High Efficiency and Sustainable Gear Lubricants for Demand Reduction

Department of Defense · Phase Phase II

$2.0Mawardedfunded 2025-08-21Company site →

Insight Rail LLC

Columbia, SC · 4 employees

Mobile, Non-Contact System for RNT and Rail Stress Measurements

Department of Transportation · Phase Phase I

$206kawardedfunded 2025-08-20

DOTY SCIENTIFIC, INC.

COLUMBIA, SC · 23 employees

An HR-MAS H/F/X/Y UHF NMR Probe for Allosteric Drug Research at Physiological Conditions

Department of Health and Human Services · Phase Phase I/Phase II

$1.3Macross 2 awardsfunded 2025-08-01Company site →

PPI PHARMACEUTICALS, LLC

IRMO, SC · 1 employee

Investigating Abbapolin PLK1 Polo Box Domain inhibitors as potential therapeutics for colorectal cancers

Department of Health and Human Services · Phase Phase I

$396kawardedfunded 2025-08-01

Doxy.me Inc.

Charleston, SC · 106 employees

Doxy.me VR: A scalable virtual reality app to facilitate evidence-based immersive telemental health

Department of Health and Human Services · Phase Phase II

$744kawardedfunded 2025-07-17Company site →

INTEGRATED BIOMETRICS, LLC

SPARTANBURG, SC · 75 employees

Wired Interconnection Cable/Adapter from Mobile Device to Biometric Collection

Department of Homeland Security · Phase Phase I

$168kawardedfunded 2025-05-07Company site →

NEUROHOPE THERAPEUTICS, INC.

GREENVILLE, SC · 2 employees · woman-owned

Dexamethasone nanotherapeutics for traumatic brain injury

Department of Defense · Phase Phase I

$249kawardedfunded 2025-02-03

PROMILEAD, LLC

COLUMBIA, SC · 1 employee

Activating TFEB to enhance the efficacy of immunotherapy for triple negative breast cancer

Department of Health and Human Services · Phase Phase I

$400kawardedfunded 2025-02-01

INVENTUS LLC

GREER, SC · 1 employee

Accurate Power Assessment in Air Force Combat Operations

Department of Defense · Phase Phase I

$75kawardedfunded 2025-01-14

SENEX BIOTECHNOLOGY, INC.

COLUMBIA, SC

Nanoparticle formulation of Mediator kinase inhibitor for the treatment of peritoneal ovarian cancer

Department of Health and Human Services · Phase Phase I

$400kawardedfunded 2024-12-13

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