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Recently funded science companies in Tennessee

30 companies in Tennessee closed federal SBIR/STTR awards in the last two years, newest first. The funding event is the signal — small companies grow right after the award lands.

APPLIED 2D MATERIALS, INC.

KNOXVILLE, TN · 1 employee

Enhancing Rotary Engine Performance with Hexagonal Boron Nitride Coatings

Department of Defense · Phase Phase I

$132kawardedfunded 2025-11-03

WHISPER AERO INC

Crossville, TN · 50 employees

Inertial Scaling for Derisking Stability and Control of Tightly Coupled Aeropropulsive Aircraft Configurations

Department of Defense · National Aeronautics and Space Administration · Phase Phase I/Phase II

$2.8Macross 3 awardsfunded 2025-10-22Company site →

PANGEA LLC

NASHVILLE, TN · 5 employees

SBIR Phase I: Cloud-Based Platform for Comprehensive AI Robustness Assessment with Dual Optimization for Accuracy and Robustness

National Science Foundation · Phase Phase I

$305kawardedfunded 2025-10-01Company site →

INTERNATIONAL FEMTOSCIENCE, INCORPORATED

NASHVILLE, TN · 7 employees

High-Temperature, Substrate-Agnostic Fine-Line Additive Metallization with Advanced Interconnects

National Aeronautics and Space Administration · Phase Phase I

$150kawardedfunded 2025-09-26Company site →

VERACITY NUCLEAR, LLC

LENOIR CITY, TN · 5 employees

Methodology for Improving Accuracy of Nuclear Industry Codes based on VERA

Department of Energy · Phase Phase I

$613kacross 3 awardsfunded 2025-09-26Company site →

ENDEAVOR COMPOSITES, INC.

KNOXVILLE, TN · 11 employees

VORTEX-C: Versatile Out-of-Clave Reinforcement Technology for Expeditionary Composites

Department of Defense · National Science Foundation · Phase Phase I/Phase II

$3.1Macross 4 awardsfunded 2025-09-25Company site →

SEAK Therapeutics, LLC

Memphis, TN · 4 employees

Development of a potent and highly brain-penetrable antimitotic agent SEAK193 to treat breast cancer brain metastasis

Department of Health and Human Services · Phase Phase I

$400kawardedfunded 2025-09-19

Fibarcode, LLC

Knoxville, TN · 1 employee

STTR Fast-Track: Photonic Particles and Fibers for Textile Tracing

National Science Foundation · Phase Phase I/Phase II

$1.6Macross 2 awardsfunded 2025-09-15Company site →

ORION THERAPEUTICS INC.

KNOXVILLE, TN · 1 employee

STTR Phase II: Multifunctional Lipid Nanoparticle Delivery System for Targeted Delivery of Vascular RNA Therapeutics

National Science Foundation · Phase Phase II

$1.2Mawardedfunded 2025-09-15

FC RENEW, LLC

Knoxville, TN · 6 employees

SBIR Phase II: Renewable Platinum Catalyst for Fuel Cell Applications

National Science Foundation · Phase Phase II

$1.2Mawardedfunded 2025-09-15Company site →

METAMORPHIX, INC.

COLLIERVILLE, TN · 3 employees

Mental Health Early Detection Platform

Department of Education · Phase Phase II

$1.0Mawardedfunded 2025-09-12

Zigguratum, Inc.

Chattanooga, TN · 13 employees

ESCAPE - Enhancing Security Capabilities through an Analytic Platform Ecosystem - Schema and Entity Resolution Phase 2

Department of Defense · Phase Phase II

$1.8Mawardedfunded 2025-09-12Company site →

Foundation Instruments, Inc.

Collierville, TN · 4 employees

SBIR Phase I: Evaluating the Feasibility of a HAA-Meter for Affordable, Onsite Monitoring of Haloacetic Acids in Drinking Water Plants with

Department of Health and Human Services · Phase Phase I

$309kawardedfunded 2025-09-01Company site →

Corami Biotech

Memphis, TN · 2 employees · woman-owned

Minimally Invasive Local Delivery of Cardiac Gene Therapy

Department of Health and Human Services · Phase Phase II

$1.3Mawardedfunded 2025-09-01Company site →

SPEAR LABS LLC

CHARLOTTE, TN · 4 employees

SKYLAR™ Canine Cranial System

Department of Defense · Phase Phase I

$249kawardedfunded 2025-08-07Company site →

RELIABLE MICROSYSTEMS LLC

FRANKLIN, TN · 12 employees

Radiation Hardened Gallium Nitride Electronics

Department of Defense · Phase Phase I

$140kawardedfunded 2025-08-01Company site →

DECODE HEALTH, INC.

Nashville, TN · 14 employees

Multivariate machine learning analysis of blood-based RNA expression profiles to distinguish relapsing-remitting and progressive forms of mu

Department of Health and Human Services · Phase Phase II

$979kawardedfunded 2025-08-01Company site →

BRANCH TECHNOLOGY, INC.

CHATTANOOGA, TN · 30 employees

Freeform 3D Printing of a Tall Lunar Tower

National Aeronautics and Space Administration · Phase Phase II

$850kawardedfunded 2025-07-29

HEROWEAR LLC

NASHVILLE, TN · 25 employees

Multipurpose Enhanced Safety Harness (MESH) to Assist Lifting, Reduce Injuries, and Improve Inventory Management and Emergency Response

Department of Defense · Phase Phase I

$500kacross 2 awardsfunded 2025-07-29Company site →

VEXTEC Corporation

BRENTWOOD, TN · 6 employees

Limited-Life Probabilistic Performance Prediction of Metallic Materials

Department of Defense · Phase Phase I/Phase II

$1.5Macross 2 awardsfunded 2025-07-16Company site →

TERRA WATTS INC.

COOKEVILLE, TN · 2 employees · woman-owned

STTR Phase I: Development of Earth-Based, Long-Range Wireless Power Transfer for Subsurface IoT Systems

National Science Foundation · Phase Phase I

$305kawardedfunded 2025-07-15Company site →

DYNAMIC STRUCTURES AND MATERIALS, LLC

FRANKLIN, TN · 24 employees

High-Capacity Balance with Tailored Compliance

Department of Defense · Phase Phase I

$140kawardedfunded 2025-06-09Company site →

AVIATION RESOURCES AND CONSULTING SERVICES, LLC

COOKEVILLE, TN · 10 employees

Battle-Damage Data Recording System (BDDRS)

Department of Defense · Phase Phase II

$3.0Macross 2 awardsfunded 2025-05-22Company site →

GLOYER-TAYLOR LABORATORIES INC

TULLAHOMA, TN · 20 employees

Compact Neon Recovery, Purification, and Liquefaction System

Department of Defense · Phase Phase I

$180kawardedfunded 2025-03-31Company site →

MINCO TECHNOLOGIES LLC

COOKEVILLE, TN · 2 employees

High Energy Density Logistics Fueled Power System

Department of Defense · Phase Phase I

$255kawardedfunded 2025-03-05Company site →

DUET BIOSYSTEMS, INC

NASHVILLE, TN · 4 employees

STTR Phase I: New Paradigm for Combination Drug Optimization and Discovery

National Science Foundation · Phase Phase I

$275kawardedfunded 2025-03-01

RJ MATTHEWS LLC

Brentwood, TN · 2 employees

Multimodal Image Fusion with 3dIV/Fusion

Department of Defense · Phase Phase II

$1.4Mawardedfunded 2025-02-24Company site →

ARENA LABS, INC

NASHVILLE, TN · 16 employees

Empowering Provider Well-being: A Holistic Approach with Arena Strive, Integrating Insights, Coaching, and Biometric Feedback for Optimal Pe

Department of Defense · Phase Phase I

$109kawardedfunded 2025-01-14

TensorX, Inc.

NASHVILLE, TN · 5 employees

Exploring PWSA to Optimize Transport Layer Networking

Department of Defense · Phase Phase I/Phase II

$2.0Macross 2 awardsfunded 2024-12-13Company site →

STATHEROS LLC

KNOXVILLE, TN · 6 employees

SIDIOUS: Synthetic Intelligence for a Dynamically Interactive Operational User Surrogate

Department of Defense · Phase Phase II

$1.8Mawardedfunded 2024-11-07Company site →

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